公开(公告)号：US20140011227A1

公开(公告)日：2014-01-09

申请号：US13867533

申请日：2013-04-22

Applicant: Agency for Science, Technology and Research

Inventor： Andrew Chwee Aun WAN ,  Tze Chiun LIM ,  Meng Fatt LEONG ,  Jackie Y. YING ,  Jerry Kah Chin TOH

IPC: C12Q1/02

CPC classification number: C12Q1/025 ,  A61K35/35 ,  A61K35/36 ,  A61K47/26 ,  C12N5/0627 ,  C12N5/0666 ,  C12N11/10 ,  C12N2501/12 ,  C12N2501/15 ,  G01N33/5088

Abstract: A fibrous structure comprising an assembly of hair follicle cells within a fibrous matrix.

Abstract translation: 纤维结构，其包含在纤维基质内的毛囊细胞的组合。

公开(公告)号：US20170342373A1

公开(公告)日：2017-11-30

申请号：US15540756

申请日：2015-12-30

Applicant: Agency for Science, Technology and Research

Inventor： Andrew Chwee Aun WAN ,  Meng Fatt LEONG ,  Tze Chiun LIM ,  Hong Fang LU

IPC: C12N5/00 ,  A61K35/12 ,  A61K35/00

CPC classification number: C12N5/0062 ,  A61K35/00 ,  A61K35/12 ,  C12N5/00

Abstract: In one example, the present invention refers to a method of making or producing a self-supporting cellular construct having a continuous channel within its central cavity, comprising the steps of providing a mould with a central opening, wherein the mould encloses a volume around the central opening (hole) capable of housing a plurality of cells. Each of the plurality of self-supporting cellular constructs, having a central opening in a series adjacent to one another such, is placed so that the central opening of each of the self-supporting cellular constructs having a central opening is aligned to one another to thereby form, for example, a continuous channel within its central cavity.