公开(公告)号：US20230416733A1

公开(公告)日：2023-12-28

申请号：US18332464

申请日：2023-06-09

Applicant: Agilent Technologies, Inc.

Inventor： Daniel E. RYAN ,  Douglas J. DELLINGER ,  Jeffrey R. SAMPSON ,  Robert KAISER ,  Joel MYERSON

IPC: C12N15/11 ,  C12N9/22 ,  C07H21/02 ,  C12N15/113 ,  C12N15/90 ,  C12Q1/6876

CPC classification number: C12N15/111 ,  C12N9/22 ,  C07H21/02 ,  C12N15/113 ,  C12N15/907 ,  C12Q1/6876 ,  C12N2310/10 ,  C12N2310/312 ,  C12N2310/323 ,  C12N2310/333 ,  C12N2310/346 ,  C12N2310/3517 ,  C12N2320/51 ,  C12N2320/53 ,  C12N2330/31 ,  C12N2310/20 ,  C12N2310/315 ,  C12N2310/3231 ,  C12N2310/335 ,  C12N2310/531 ,  C12N2310/321 ,  C12N2310/322

Abstract: The present invention relates to modified guide RNAs and their use in clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems.

公开(公告)号：US20250092389A1

公开(公告)日：2025-03-20

申请号：US18883302

申请日：2024-09-12

Applicant: Agilent Technologies, Inc.

Inventor： Daniel E. RYAN ,  Douglas J. DELLINGER ,  Jeffrey R. SAMPSON ,  Robert KAISER ,  Joel MYERSON

IPC: C12N15/11 ,  C07H21/02 ,  C12N9/22 ,  C12N15/113 ,  C12N15/90 ,  C12Q1/6876

Abstract: The present invention relates to modified guide RNAs and their use in clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems.

公开(公告)号：US20210079389A1

公开(公告)日：2021-03-18

申请号：US17103678

申请日：2020-11-24

Applicant: Agilent Technologies, Inc.

Inventor： Daniel E. RYAN ,  Douglas J. DELLINGER ,  Jeffrey R. SAMPSON ,  Robert KAISER ,  Joel MYERSON

IPC: C12N15/11 ,  C12N9/22 ,  C07H21/02 ,  C12N15/113 ,  C12N15/90 ,  C12Q1/6876

Abstract: The present invention relates to modified guide RNAs and their use in clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems.