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公开(公告)号：US08298830B2
公开(公告)日：2012-10-30
申请号：US12795279
申请日：2010-06-07
IPC分类号： G01N33/00
CPC分类号： G01N21/7703 , G01N33/0057 , H01S3/067 , H01S3/178 , H01S5/12 , H01S5/36 , H01S2301/02
摘要： The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances. In another set of embodiments, the polymer may include one or more pendant aromatic rings. In yet another set of embodiments, the polymer may be substantially encapsulated in a hydrocarbon. In still another set of embodiments, the polymer may be substantially resistant to photobleaching. In certain aspects, the polymer may be useful in the detection of explosive agents, such as 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
摘要翻译： 本发明一般涉及具有允许聚合物用于检测分析物的激光特性的聚合物。 在一个方面，聚合物在与分析物相互作用时可以表现出可以以某种方式确定的激光特性的变化。 例如，分析物与聚合物的相互作用可能影响聚合物达到允许发生光子的受激发射的激发态的能力，这可以被确定，从而确定分析物。 在另一方面，聚合物在与分析物相互作用时可能表现出相对于与分析物相互作用时聚合物自发发射变化的至少10倍的受激发射的变化。 在某些情况下，聚合物可以是共轭聚合物。 在一组实施方案中，聚合物包括一个或多个烃侧链，其在一些情况下可以平行于聚合物主链。 在另一组实施方案中，聚合物可以包括一个或多个芳族环。 在又一组实施方案中，聚合物可以基本上包封在烃中。 在又一组实施方案中，聚合物可以基本上抵抗光漂白。 在某些方面，聚合物可用于检测爆炸剂，例如2,4,6-三硝基甲苯（TNT）和2,4-二硝基甲苯（DNT）。
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公开(公告)号：US20100310424A1
公开(公告)日：2010-12-09
申请号：US12795279
申请日：2010-06-07
CPC分类号： G01N21/7703 , G01N33/0057 , H01S3/067 , H01S3/178 , H01S5/12 , H01S5/36 , H01S2301/02
摘要： The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances. In another set of embodiments, the polymer may include one or more pendant aromatic rings. In yet another set of embodiments, the polymer may be substantially encapsulated in a hydrocarbon. In still another set of embodiments, the polymer may be substantially resistant to photobleaching. In certain aspects, the polymer may be useful in the detection of explosive agents, such as 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
摘要翻译： 本发明一般涉及具有允许聚合物用于检测分析物的激光特性的聚合物。 在一个方面，聚合物在与分析物相互作用时可以表现出可以以某种方式确定的激光特性的变化。 例如，分析物与聚合物的相互作用可能影响聚合物达到允许发生光子的受激发射的激发态的能力，这可以被确定，从而确定分析物。 在另一方面，聚合物在与分析物相互作用时可能表现出相对于与分析物相互作用时聚合物自发发射变化的至少10倍的受激发射的变化。 在某些情况下，聚合物可以是共轭聚合物。 在一组实施方案中，聚合物包括一个或多个烃侧链，其在一些情况下可以平行于聚合物主链。 在另一组实施方案中，聚合物可以包括一个或多个芳族环。 在又一组实施方案中，聚合物可以基本上包封在烃中。 在又一组实施方案中，聚合物可以基本上抵抗光漂白。 在某些方面，聚合物可用于检测爆炸剂，例如2,4,6-三硝基甲苯（TNT）和2,4-二硝基甲苯（DNT）。
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公开(公告)号：US07759127B2
公开(公告)日：2010-07-20
申请号：US11005631
申请日：2004-12-06
IPC分类号： G01N33/00
CPC分类号： G01N21/7703 , G01N33/0057 , H01S3/067 , H01S3/178 , H01S5/12 , H01S5/36 , H01S2301/02
摘要： The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances. In another set of embodiments, the polymer may include one or more pendant aromatic rings. In yet another set of embodiments, the polymer may be substantially encapsulated in a hydrocarbon. In still another set of embodiments, the polymer may be substantially resistant to photobleaching. In certain aspects, the polymer may be useful in the detection of explosive agents, such as 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
摘要翻译： 本发明一般涉及具有允许聚合物用于检测分析物的激光特性的聚合物。 在一个方面，聚合物在与分析物相互作用时可以表现出可以以某种方式确定的激光特性的变化。 例如，分析物与聚合物的相互作用可能影响聚合物达到允许发生光子的受激发射的激发态的能力，这可以被确定，从而确定分析物。 在另一方面，聚合物在与分析物相互作用时可能表现出相对于与分析物相互作用时聚合物自发发射变化的至少10倍的受激发射的变化。 在某些情况下，聚合物可以是共轭聚合物。 在一组实施方案中，聚合物包括一个或多个烃侧链，其在一些情况下可以平行于聚合物主链。 在另一组实施方案中，聚合物可以包括一个或多个芳族环。 在又一组实施方案中，聚合物可以基本上包封在烃中。 在又一组实施方案中，聚合物可以基本上抵抗光漂白。 在某些方面，聚合物可用于检测爆炸剂，例如2,4,6-三硝基甲苯（TNT）和2,4-二硝基甲苯（DNT）。
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公开(公告)号：US20060073607A1
公开(公告)日：2006-04-06
申请号：US11005631
申请日：2004-12-06
申请人： Aimee Rose , Timothy Swager , Zhengguo Zhu , Vladimir Bulovic , Conor Madigan
发明人： Aimee Rose , Timothy Swager , Zhengguo Zhu , Vladimir Bulovic , Conor Madigan
IPC分类号： G01N30/00
CPC分类号： G01N21/7703 , G01N33/0057 , H01S3/067 , H01S3/178 , H01S5/12 , H01S5/36 , H01S2301/02
摘要： The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances. In another set of embodiments, the polymer may include one or more pendant aromatic rings. In yet another set of embodiments, the polymer may be substantially encapsulated in a hydrocarbon. In still another set of embodiments, the polymer may be substantially resistant to photobleaching. In certain aspects, the polymer may be useful in the detection of explosive agents, such as 2,4,6-trinitrotoluene (TNT) and 2,4-dinitrotoluene (DNT).
摘要翻译： 本发明一般涉及具有允许聚合物用于检测分析物的激光特性的聚合物。 在一个方面，聚合物在与分析物相互作用时可以表现出可以以某种方式确定的激光特性的变化。 例如，分析物与聚合物的相互作用可能影响聚合物达到允许发生光子的受激发射的激发态的能力，这可以被确定，从而确定分析物。 在另一方面，聚合物在与分析物相互作用时可能表现出相对于与分析物相互作用时聚合物自发发射变化的至少10倍的受激发射的变化。 在某些情况下，聚合物可以是共轭聚合物。 在一组实施方案中，聚合物包括一个或多个烃侧链，其在一些情况下可以平行于聚合物主链。 在另一组实施方案中，聚合物可以包括一个或多个芳族环。 在又一组实施方案中，聚合物可以基本上包封在烃中。 在又一组实施方案中，聚合物可以基本上抵抗光漂白。 在某些方面，聚合物可用于检测爆炸剂，例如2,4,6-三硝基甲苯（TNT）和2,4-二硝基甲苯（DNT）。
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公开(公告)号：US07799573B2
公开(公告)日：2010-09-21
申请号：US11784208
申请日：2007-04-05
IPC分类号： G01N33/00
CPC分类号： G01N21/76 , C07D471/14 , G01N21/643 , G01N21/783 , G01N33/0057 , G01N2021/7786 , G01N2201/0221 , Y10T436/10 , Y10T436/20 , Y10T436/206664
摘要： The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
摘要翻译： 本发明提供了一系列与爆炸物的测定相关的系统，装置和方法，例如过氧化物或过氧化物前体以及其他物质。 本发明的实施方案可以允许怀疑含有爆炸物（例如，过氧化物）或其它物质的样品与反应物相互作用，其中样品可能反应并引起来自反应物的光发射。 本发明的优点可以包括用于确定基于过氧化物的爆炸物的装置的简化，其中装置是便携式的，并且在一些情况下是一次性的。 其他优点可以包括制造和操作的相对容易。
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公开(公告)号：US20120107946A1
公开(公告)日：2012-05-03
申请号：US12833245
申请日：2010-07-09
IPC分类号： G01N21/75
CPC分类号： G01N21/76 , C07D471/14 , G01N21/643 , G01N21/783 , G01N33/0057 , G01N2021/7786 , G01N2201/0221 , Y10T436/10 , Y10T436/20 , Y10T436/206664
摘要： The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
摘要翻译： 本发明提供了一系列与爆炸物的测定相关的系统，装置和方法，例如过氧化物或过氧化物前体以及其他物质。 本发明的实施方案可以允许怀疑含有爆炸物（例如，过氧化物）或其它物质的样品与反应物相互作用，其中样品可能反应并引起来自反应物的光发射。 本发明的优点可以包括用于确定基于过氧化物的爆炸物的装置的简化，其中装置是便携式的，并且在一些情况下是一次性的。 其他优点可以包括制造和操作的相对容易。
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公开(公告)号：US09005524B2
公开(公告)日：2015-04-14
申请号：US12833245
申请日：2010-07-09
IPC分类号： G01N21/75 , G01N33/22 , C07D471/14 , G01N21/64 , G01N33/00 , G01N21/76 , G01N21/78 , G01N21/77
CPC分类号： G01N21/76 , C07D471/14 , G01N21/643 , G01N21/783 , G01N33/0057 , G01N2021/7786 , G01N2201/0221 , Y10T436/10 , Y10T436/20 , Y10T436/206664
摘要： The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
摘要翻译： 本发明提供了一系列与爆炸物的测定相关的系统，装置和方法，例如过氧化物或过氧化物前体以及其他物质。 本发明的实施方案可以允许怀疑含有爆炸物（例如，过氧化物）或其它物质的样品与反应物相互作用，其中样品可能反应并引起来自反应物的光发射。 本发明的优点可以包括用于确定基于过氧化物的爆炸物的装置的简化，其中装置是便携式的，并且在一些情况下是一次性的。 其他优点可以包括制造和操作的相对容易。
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公开(公告)号：US20080248578A1
公开(公告)日：2008-10-09
申请号：US11784208
申请日：2007-04-05
CPC分类号： G01N21/76 , C07D471/14 , G01N21/643 , G01N21/783 , G01N33/0057 , G01N2021/7786 , G01N2201/0221 , Y10T436/10 , Y10T436/20 , Y10T436/206664
摘要： The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
摘要翻译： 本发明提供了一系列与爆炸物的测定相关的系统，装置和方法，例如过氧化物或过氧化物前体以及其他物质。 本发明的实施方案可以允许怀疑含有爆炸物（例如，过氧化物）或其它物质的样品与反应物相互作用，其中样品可能反应并引起来自反应物的光发射。 本发明的优点可以包括用于确定基于过氧化物的爆炸物的装置的简化，其中装置是便携式的，并且在一些情况下是一次性的。 其他优点可以包括制造和操作的相对容易。
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公开(公告)号：US20070111321A1
公开(公告)日：2007-05-17
申请号：US11514092
申请日：2006-08-31
申请人： Robert Deans , Aimee Rose , Marcus Grone
发明人： Robert Deans , Aimee Rose , Marcus Grone
IPC分类号： G01N21/75
CPC分类号： G01N21/76 , G01N33/0057
摘要： The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
摘要翻译： 本发明提供了一系列与爆炸物的测定相关的系统，装置和方法，例如过氧化物或过氧化物前体以及其他物质。 本发明的实施方案可以允许怀疑含有爆炸物（例如，过氧化物）或其它物质的样品与反应物相互作用，其中样品可能反应并引起来自反应物的光发射。 本发明的优点可以包括用于确定基于过氧化物的爆炸物的装置的简化，其中装置是便携式的，并且在一些情况下是一次性的。 其他优点可以包括制造和操作的相对容易。
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公开(公告)号：US20140017803A1
公开(公告)日：2014-01-16
申请号：US14007822
申请日：2011-03-28
申请人： Robert Deans , Aimee Rose , William McDaniel , Aaron Thompson , Steven Shaull
发明人： Robert Deans , Aimee Rose , William McDaniel , Aaron Thompson , Steven Shaull
IPC分类号： G01N21/64
CPC分类号： G01N21/6428 , G01N21/7703 , G01N33/52 , G01N33/94 , G01N2021/7786
摘要： Embodiments described herein provide materials, devices, and methods relating to the determination of analytes such as drugs, toxins, explosives, other controlled substances and contraband materials, and the like. In some embodiments, the analyte may be detected in vapor phase. Some embodiments may allow for highly sensitive and essentially instantaneous detection of analytes including drugs.
摘要翻译： 本文所述的实施方案提供了与分析物如药物，毒素，爆炸物，其它受控物质和违禁物质等的测定相关的材料，装置和方法。 在一些实施方案中，可以在气相中检测分析物。 一些实施方案可以允许对包括药物在内的分析物进行高度灵敏和基本上即时的检测。
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