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    Nitrogen-containing aromatic derivatives
    3.
    发明授权
    Nitrogen-containing aromatic derivatives 有权
    含氮芳香族衍生物

    公开(公告)号：US07109219B2

    公开(公告)日：2006-09-19

    申请号：US10651496

    申请日：2003-08-29

    申请人： Akihiko Tsuruoka ,  Tomohiro Matsushima ,  Masayuki Matsukura ,  Kazuki Miyazaki ,  Keiko Takahashi ,  Junichi Kamata ,  Yoshio Fukuda

    发明人： Akihiko Tsuruoka ,  Tomohiro Matsushima ,  Masayuki Matsukura ,  Kazuki Miyazaki ,  Keiko Takahashi ,  Junichi Kamata ,  Yoshio Fukuda

    IPC分类号： A61K31/4439 ,  C07D401/12

    CPC分类号： C07D401/12 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/506 ,  A61K31/5377 ,  C07D401/14 ,  C07D403/12 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

    摘要： A compound represented by the general formula: wherein X1 represents a nitrogen atom or a group represented by the formula —CR10═; X2 represents a nitrogen atom or a group represented by the formula —CR11═; Y represents an oxygen atom or the like; R1 represents a C1-6 alkoxy group, an optionally substituted C6-10 aryloxy group, a group represented by the formula —NR12aR12b or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like; R3, R4, R5, R6, R7, R8, R10 and R11 each independently represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or the like; R9 represents a group represented by the formula —NR12aR12b or the like; and R12a and R12b each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, a salt thereof, or a hydrate of the foregoing.

    摘要翻译： 由以下通式表示的化合物：其中X 1表示氮原子或由式-CR 10 - 表示的基团。 X 2表示氮原子或由式-CR 11-11表示的基团。 Y表示氧原子等; R 1表示C 1-6烷氧基，任选取代的C 6-10芳氧基，由-NR表示的基团 12b等等;或者， R 2表示氢原子，任选取代的C 1-6烷基等; R 3，R 4，R 5，R 6，R 7， R 8，R 10和R 11各自独立地表示氢原子，卤素原子，任选取代的C 1-6 烷基等; R 9表示由式-NR 12 R 12 R 12等表示的基团; 和R 12a和R 12b各自独立地表示氢原子，任选取代的C 1-6烷基等，盐 或上述的水合物。

    Nitrogen-containing aromatic derivatives
    7.
    发明授权
    Nitrogen-containing aromatic derivatives 有权
    含氮芳香族衍生物

    公开(公告)号：US07468380B2

    公开(公告)日：2008-12-23

    申请号：US11507082

    申请日：2006-08-18

    申请人： Akihiko Tsuruoka ,  Tomohiro Matsushima ,  Masayuki Matsukura ,  Kazuki Miyazaki ,  Keiko Takahashi ,  Junichi Kamata ,  Yoshio Fukuda

    发明人： Akihiko Tsuruoka ,  Tomohiro Matsushima ,  Masayuki Matsukura ,  Kazuki Miyazaki ,  Keiko Takahashi ,  Junichi Kamata ,  Yoshio Fukuda

    IPC分类号： A61K31/4439 ,  C07D401/12

    CPC分类号： C07D401/12 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/506 ,  A61K31/5377 ,  C07D401/14 ,  C07D403/12 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

    摘要： A compound represented by the general formula: wherein X1 represents a nitrogen atom or a group represented by the formula —CR10═; X2 represents a nitrogen atom or a group represented by the formula —CR11═; Y represents an oxygen atom or the like; R1 represents a C1-6 alkoxy group, an optionally substituted C6-10 aryloxy group, a group represented by the formula —NR12aR12b or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like; R3, R4, R5, R6, R7, R8, R10 and R11 each independently represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or the like; R9 represents a group represented by the formula —NR16aR16b or the like; and R12a, R12b, R16a and R16b each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, a salt thereof, or a hydrate of the foregoing.

    摘要翻译： 由以下通式表示的化合物：其中X1表示氮原子或由式-CR10-表示的基团; X2表示氮原子或式-CR11-表示的基团; Y表示氧原子等; R1表示C1-6烷氧基，任选取代的C6-10芳氧基，由式-NR12aR12b表示的基团等; R 2表示氢原子，任选取代的C 1-6烷基等; R 3，R 4，R 5，R 6，R 7，R 8，R 10和R 11各自独立地表示氢原子，卤素原子，任选取代的C 1-6烷基等; R9表示由式-NR16aR16b等表示的基团; R12a，R12b，R16a和R16b各自独立地表示氢原子，任意取代的C 1-6烷基等，其盐或上述的水合物。

    Nitrogen-containing aromatic derivatives
    8.
    发明申请
    Nitrogen-containing aromatic derivatives 有权
    含氮芳香族衍生物

    公开(公告)号：US20070004764A1

    公开(公告)日：2007-01-04

    申请号：US11507082

    申请日：2006-08-18

    申请人： Akihiko Tsuruoka ,  Tomohiro Matsushima ,  Masayuki Matsukura ,  Kazuki Miyazaki ,  Keiko Takahashi ,  Junichi Kamata ,  Yoshio Fukuda

    发明人： Akihiko Tsuruoka ,  Tomohiro Matsushima ,  Masayuki Matsukura ,  Kazuki Miyazaki ,  Keiko Takahashi ,  Junichi Kamata ,  Yoshio Fukuda

    IPC分类号： A61K31/506 ,  A61K31/4439 ,  C07D403/02

    CPC分类号： C07D401/12 ,  A61K31/4439 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/506 ,  A61K31/5377 ,  C07D401/14 ,  C07D403/12 ,  C07D405/14 ,  C07D409/14 ,  C07D417/14

    摘要： A compound represented by the general formula: wherein X1 represents a nitrogen atom or a group represented by the formula —CR10═; X2 represents a nitrogen atom or a group represented by the formula —CR11═; Y represents an oxygen atom or the like; R1 represents a C1-6 alkoxy group, an optionally substituted C6-10 aryloxy group, a group represented by the formula —NR12aR12b or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like; R3, R4, R5, R6, R7, R8, R10 and R11 each independently represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or the like; R9 represents a group represented by the formula —NR16aR16b or the like; and R12a, R12b, R16a and R16b each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, a salt thereof, or a hydrate of the foregoing.

    摘要翻译： 由以下通式表示的化合物：其中X 1表示氮原子或由式-CR 10 - 表示的基团。 X 2表示氮原子或由式-CR 11-11表示的基团。 Y表示氧原子等; R 1表示C 1-6烷氧基，任选取代的C 6-10芳氧基，由-NR表示的基团 12b等等;或者， R 2表示氢原子，任选取代的C 1-6烷基等; R 3，R 4，R 5，R 6，R 7， R 8，R 10和R 11各自独立地表示氢原子，卤素原子，任选取代的C 1-6 烷基等; R 9表示由式-NR 16a R 16b等表示的基团; R 12a，R 12b，R 16a和R 16b各自独立地表示氢原子，任意取代的 C 1-6烷基等，其盐或上述的水合物。