专利检索 ap:"Takako Yoshiba" 第 1 页

1.

发明授权
Nitrogen-containing aromatic derivatives 有权
标题翻译：含氮芳香族衍生物

公开(公告)号：US07253286B2

公开(公告)日：2007-08-07

申请号：US10420466

申请日：2003-04-18

申请人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto

发明人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto

IPC分类号： A61K31/47 , C07D215/16

CPC分类号： C07D213/73 , A61K31/4706 , A61K31/4745 , A61K31/517 , A61K31/519 , C07D207/34 , C07D213/26 , C07D213/68 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/18 , C07D215/233 , C07D215/36 , C07D215/38 , C07D215/48 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/88 , C07D249/04 , C07D261/14 , C07D277/48 , C07D307/68 , C07D319/06 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04

摘要： Compounds represented by the following general formula: [wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—, Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.)], salts thereof or hydrates of the foregoing.

摘要翻译： 由以下通式表示的化合物：其中A为任选取代的5至14元杂环基等; X-O是-O - ， - S-等; Y是任选取代的C 6-14芳基，任选取代的5至14元杂环基等; 并且T 1是由以下通式表示的基团：其中E是单键或-N（R 2）2 - R 1，G 1和R 2各自独立地表示氢原子，任选取代的C 1-6烷基等，Z

2.

发明授权
Carbapenem compound crystals and interjection preparations 失效
标题翻译：碳青霉烯复合晶体和注射剂

公开(公告)号：US07084268B1

公开(公告)日：2006-08-01

申请号：US09979679

申请日：2000-06-05

申请人： Hiroyuki Chiba , Masahiko Tsujii , Astsushi Koiwa , Shin Sakurai , Akio Kayano , Hiroyuki Ishizuka , Hiroyuki Saito , Taiju Nakamura , Ikuo Kushida , Yasuyuki Suzuki , Takako Yoshiba , Kazuhide Ashizawa , Masahiro Sakurai , Eiichi Yamamoto

发明人： Hiroyuki Chiba , Masahiko Tsujii , Astsushi Koiwa , Shin Sakurai , Akio Kayano , Hiroyuki Ishizuka , Hiroyuki Saito , Taiju Nakamura , Ikuo Kushida , Yasuyuki Suzuki , Takako Yoshiba , Kazuhide Ashizawa , Masahiro Sakurai , Eiichi Yamamoto

IPC分类号： C07D477/20 , A61K31/407 , A61P31/04

CPC分类号： C07D477/20 , A61K31/407

摘要： The present invention provides carbapenem hydrochloride trihydrate crystals, which are chemically stable, easily purified and useful as antimicrobial agents, a process for producing them, and a powdery charged preparation for injection containing them. That is, it provides carbapenem hydrochloride trihydrate crystals having a powdery X-ray diffraction pattern containing lattice distances (d) of 9.0, 4.1 and 2.8 Å, a process for producing them, and a powdery charged preparation for injection containing them.

摘要翻译： 本发明提供化学稳定，易于纯化和用作抗微生物剂的盐酸碳青霉烯盐酸盐三水合物晶体，其制备方法和含有它们的注射用粉末状药物制剂。也就是说，它提供了具有包含晶格距离（d）为9.0,4.1和2.8的粉末X射线衍射图的碳青霉烯盐酸盐三水合物晶体，其制备方法和含有它们的注射用粉末状药物制剂。

3.

发明申请
Carbapenem compound crystals and injection preparations 审中-公开
标题翻译：碳青霉烯复合晶体和注射剂

公开(公告)号：US20060040916A1

公开(公告)日：2006-02-23

申请号：US11259509

申请日：2005-10-26

申请人： Hiroyuki Chiba , Masahiko Tsujii , Astsushi Koiwa , Shin Sakurai , Akio Kayano , Hiroyuki Ishizuka , Hiroyuki Saito , Taiju Nakamura , Ikuo Kushida , Yasuyuki Suzuki , Takako Yoshiba , Kazuhide Ashizawa , Masahiro Sakurai , Eiichi Yamamoto

发明人： Hiroyuki Chiba , Masahiko Tsujii , Astsushi Koiwa , Shin Sakurai , Akio Kayano , Hiroyuki Ishizuka , Hiroyuki Saito , Taiju Nakamura , Ikuo Kushida , Yasuyuki Suzuki , Takako Yoshiba , Kazuhide Ashizawa , Masahiro Sakurai , Eiichi Yamamoto

IPC分类号： C07D487/04 , A61K31/407

CPC分类号： C07D477/20 , A61K31/407

摘要： The present invention provides carbapenem hydrochloride trihydrate crystals, which are chemically stable, easily purified and useful as antimicrobial agents, a process for producing them, and a powdery charged preparation for injection containing them. That is, it provides carbapenem hydrochloride trihydrate crystals having a powdery X-ray diffraction pattern containing lattice distances (d) of 9.0, 4.1 and 2.8 Å, a process for producing them, and a powdery charged preparation for injection containing them.

摘要翻译： 本发明提供化学稳定，易于纯化和用作抗微生物剂的盐酸碳青霉烯盐酸盐三水合物晶体，其制备方法和含有它们的注射用粉末状药物制剂。也就是说，它提供了具有包含晶格距离（d）为9.0,4.1和2.8的粉末X射线衍射图的碳青霉烯盐酸盐三水合物晶体，其制备方法和含有它们的注射用粉末状药物制剂。

4.

发明申请
NITROGEN-CONTAINING AROMATIC DERIVATIVES 有权
标题翻译：含氮的芳族衍生物

公开(公告)号：US20110118470A1

公开(公告)日：2011-05-19

申请号：US12986638

申请日：2011-01-07

申请人： Yasuhiro FUNAHASHI , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto

发明人： Yasuhiro FUNAHASHI , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto

IPC分类号： C07D213/74 , C07D401/04 , C07D401/14 , C07D417/12

CPC分类号： C07D213/73 , A61K31/4706 , A61K31/4745 , A61K31/517 , A61K31/519 , C07D207/34 , C07D213/26 , C07D213/68 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/18 , C07D215/233 , C07D215/36 , C07D215/38 , C07D215/48 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/88 , C07D249/04 , C07D261/14 , C07D277/48 , C07D307/68 , C07D319/06 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04

摘要： Compounds represented by the following general formula: wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—), Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.), salts thereof or hydrates of the foregoing.

摘要翻译： 由以下通式表示的化合物：其中Ag是任选取代的5至14元杂环基等; Xg为-O-，-S-等; Yg是任选取代的C 6-14芳基，任选取代的5至14元杂环基等; Tg1为下列通式表示的基团：（其中Eg为单键或-N（Rg2） - ），Rg1和Rg2各自独立地表示氢原子，任意取代的C 1-6烷基等， Zg表示C1-8烷基，C3-8脂环族烃基，C6-14芳基等），其盐或上述的水合物。

5.

发明申请
Nitrogen-Containing Aromatic Derivatives 有权
标题翻译：含氮芳香族衍生物

公开(公告)号：US20100197911A1

公开(公告)日：2010-08-05

申请号：US12244227

申请日：2008-10-02

申请人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto

发明人： Yasuhiro Funahashi , Akihiko Tsuruoka , Masayuki Matsukura , Toru Haneda , Yoshio Fukuda , Junichi Kamata , Keiko Takahashi , Tomohiro Matsushima , Kazuki Miyazaki , Ken-ichi Nomoto , Tatsuo Watanabe , Hiroshi Obaishi , Atsumi Yamaguchi , Sachi Suzuki , Katsuji Nakamura , Fusayo Mimura , Yuji Yamamoto , Junji Matsui , Kenji Matsui , Takako Yoshiba , Yasuyuki Suzuki , Itaru Arimoto

IPC分类号： C07D487/04 , C07F7/08

CPC分类号： C07D213/73 , A61K31/4706 , A61K31/4745 , A61K31/517 , A61K31/519 , C07D207/34 , C07D213/26 , C07D213/68 , C07D213/74 , C07D213/75 , C07D213/81 , C07D213/82 , C07D215/18 , C07D215/233 , C07D215/36 , C07D215/38 , C07D215/48 , C07D239/34 , C07D239/42 , C07D239/47 , C07D239/88 , C07D249/04 , C07D261/14 , C07D277/48 , C07D307/68 , C07D319/06 , C07D401/04 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04 , C07D495/04

摘要： Compounds represented by the following general formula: [wherein Ag is an optionally substituted 5- to 14-membered heterocyclic group, etc.; Xg is —O—, —S—, etc.; Yg is an optionally substituted C6-14 aryl group, an optionally substituted 5- to 14-membered heterocyclic group, etc.; and Tg1 is a group represented by the following general formula: (wherein Eg is a single bond or —N(Rg2)—, Rg1 and Rg2 each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, etc. and Zg represents a C1-8 alkyl group, a C3-8 alicyclic hydrocarbon group, a C6-14 aryl group, etc.)], salts thereof or hydrates of the foregoing.

摘要翻译： 由以下通式表示的化合物：其中Ag是任选取代的5至14元杂环基等; Xg为-O-，-S-等; Yg是任选取代的C 6-14芳基，任选取代的5至14元杂环基等; Tg1为下列通式表示的基团：（其中Eg为单键或-N（Rg2） - ，Rg1和Rg2各自独立地表示氢原子，可以具有取代基的C1-6烷基等，Zg 表示C 1-8烷基，C 3-8脂环族烃基，C 6-14芳基等）]，其盐或前述的水合物。