Method of detecting nucleotide sequence with an intramolecular probe
    2.
    发明授权
    Method of detecting nucleotide sequence with an intramolecular probe 有权
    用分子内探针检测核苷酸序列的方法

    公开(公告)号:US08236498B2

    公开(公告)日:2012-08-07

    申请号:US12172655

    申请日:2008-07-14

    摘要: A nucleotide sequence-detecting method, including preparing a first intramolecular detecting sequence having a sequence complementary to a first sequence located at a 3′-side of the detecting site contained in the nucleotide sample and a second intramolecular detecting sequence having a sequence complementary to a second sequence located at a 5′-side of the detecting site, preparing a detecting chain containing a sequence of the detecting chain by connecting the first intramolecular detecting sequence to the 3′ terminal of the nucleotide sample and the second intramolecular detecting sequence to the 5′ terminal, allowing intramolecular hybridization at two positions of the detecting chain, connecting the 3′ terminal of the first intramolecular detecting sequence to the 5′ terminal of the second intramolecular detecting sequence, obtaining a cyclic structure, detecting the desired sequence in the nucleotide sample from the cyclic structure.

    摘要翻译: 核苷酸序列检测方法,包括制备具有与位于核苷酸样品中所含的检测位点3'侧的第一序列互补的序列的第一分子内检测序列和具有与所述核苷酸样品互补的序列的第二分子内检测序列 第二序列位于检测部位的5'侧,通过将第一分子内检测序列连接到核苷酸样品的3'末端,将第二分子内检测序列连接到5个检测链上,制备含有检测链序列的检测链 '末端,允许在检测链的两个位置进行分子内杂交,将第一分子内检测序列的3'末端连接到第二分子内检测序列的5'末端,获得环状结构,检测核苷酸样品中的所需序列 从循环结构。

    High-density capillary array for reaction and detection of fluid
    3.
    发明授权
    High-density capillary array for reaction and detection of fluid 失效
    用于反应和检测流体的高密度毛细管阵列

    公开(公告)号:US06613561B1

    公开(公告)日:2003-09-02

    申请号:US09718534

    申请日:2000-11-22

    申请人: Nobuhiko Morimoto

    发明人: Nobuhiko Morimoto

    IPC分类号: C12M134

    摘要: A high-density capillary array for reaction and detection of fluid, comprising a plurality of fluid processing capillaries arranged in parallel on one same plane, the fluid processing capillaries each comprising a reaction part for performing processing on fluid, connection parts connected to each end portion of the reaction part, and opening portions provided at ends of the connection parts, for allowing the fluid to flow into and out of the reaction part, wherein each of the fluid processing capillaries is bent at portions between the reaction part and the connection parts.

    摘要翻译: 一种用于反应和检测流体的高密度毛细管阵列,包括在同一平面上平行布置的多个流体处理毛细管,每个流体处理毛细管包括用于对流体进行处理的反应部分,连接到每个端部的连接部分 反应部分的开口部分和设置在连接部分的端部处的开口部分,用于允许流体流入和流出反应部分,其中每个流体处理毛细管在反应部分和连接部分之间的部分弯曲。

    Polymerizable, curable molding composition and a molding or coating
process using this molding composition
    4.
    发明授权
    Polymerizable, curable molding composition and a molding or coating process using this molding composition 失效
    可聚合的可固化模塑组合物和使用该模塑组合物的模制或涂覆方法

    公开(公告)号:US5589230A

    公开(公告)日:1996-12-31

    申请号:US418977

    申请日:1995-04-07

    摘要: A polymerizable curable molding composition comprising (A) 100 parts by weight of an unsaturated epoxyester resin with an acid value below 3.0, (B) 10 to 40 parts by weight of a polymerizable monomer selected from the group consisting of phenoxyethyl acrylate, 2-acroyloxyethyl-2-hydroxypropyl phthalate and mixtures thereof and (C) 1 to 5 parts by weight of a mixture of hydroxyketone oligomer and 2-hydroxy-2-methyl-1-phenylpropan-1-one. The molding composition also preferably comprises 0.5 to 5 parts by weight of polystyrene microbeads. Also provided are a molding process using the polymerizable curable molding composition and a coating process using the polymerizable curing molding composition, each process being characterized by combined exposure of the composition to UV radiation and heating.

    摘要翻译: 一种可聚合可固化的模塑组合物,其包含(A)100重量份的酸值低于3.0的不饱和环氧酯树脂,(B)10至40重量份的选自丙烯酸苯氧基乙酯,2-丙酰氧基乙基 -2-羟丙基邻苯二甲酸酯及其混合物,(C)1至5重量份羟基酮低聚物和2-羟基-2-甲基-1-苯基丙-1-酮的混合物。 成型组合物还优选包含0.5至5重量份的聚苯乙烯微珠。 还提供了使用可聚合固化模塑组合物的模塑方法和使用可聚合固化模塑组合物的涂覆方法,每种方法的特征在于将组合物组合暴露于UV辐射和加热。