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公开(公告)号：US06656178B1
公开(公告)日：2003-12-02
申请号：US09626817
申请日：2000-07-27
申请人： Albert Gerrit Veldhuizen , Gert Nijenbannin , Alec Paul Birkbeck , Gary Stuart Fenton , Martin Pfleiderer , Marc Sanders
发明人： Albert Gerrit Veldhuizen , Gert Nijenbannin , Alec Paul Birkbeck , Gary Stuart Fenton , Martin Pfleiderer , Marc Sanders
IPC分类号： A61F244
CPC分类号： A61F2/4455 , A61B2017/0256 , A61F2/0095 , A61F2/442 , A61F2/4465 , A61F2/4611 , A61F2002/2835 , A61F2002/30093 , A61F2002/30095 , A61F2002/30115 , A61F2002/30126 , A61F2002/30131 , A61F2002/30136 , A61F2002/30143 , A61F2002/30148 , A61F2002/30153 , A61F2002/3023 , A61F2002/30235 , A61F2002/30291 , A61F2002/30324 , A61F2002/30326 , A61F2002/30329 , A61F2002/30387 , A61F2002/30565 , A61F2002/30611 , A61F2002/30787 , A61F2002/30823 , A61F2002/30828 , A61F2002/30904 , A61F2002/4475 , A61F2002/448 , A61F2002/4619 , A61F2002/4622 , A61F2002/4627 , A61F2002/4628 , A61F2002/4635 , A61F2210/0019 , A61F2210/0023 , A61F2220/0025 , A61F2230/0004 , A61F2230/0006 , A61F2230/0008 , A61F2230/0013 , A61F2230/0017 , A61F2230/0019 , A61F2230/0069 , A61F2230/0091 , A61F2250/0036 , A61F2250/0037 , A61F2250/0063 , A61F2310/00023 , A61F2310/00071 , A61F2310/00077 , Y10S606/911
摘要： A vertebral-column device that is suitable to be received in an intervertebral space between two dorsal vertebrae, the prosthesis comprising a curved strip of biocompatible material. The width of the strip being such that after placement, the strip makes contact with the vertebrae. The strip is manufactured from a material that can undergo great deformations before permanent deformation arises. The strip is curved in a shape in which the extremities are situated apart from one another and the radius of the curved parts and the thickness of the strip are chosen in such a way that when the strip is bent out into an approximately straight strip, scarcely any permanent deformation arises. Thus, the strip which has been bent out into an approximately straight strip is capable of being introduced into an intervertebral space where the strip assumes its original curved shape.
摘要翻译： 一种适于被接纳在两个背椎之间的椎间空间中的椎骨柱装置，所述假体包括生物相容性材料的弯曲带。 条的宽度使得在放置之后，带与椎骨接触。 带材由永久变形产生之前能够经受很大变形的材料制成。 条带弯曲成四肢彼此分开的形状，并且弯曲部分的半径和条的厚度以这样的方式选择，即当条带弯曲成大致直的条带时，几乎不 任何永久变形都会出现。 因此，已经弯曲成大致直的条带的条带能够被引入到条带呈现其原始弯曲形状的椎间空间中。
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公开(公告)号：US08518023B2
公开(公告)日：2013-08-27
申请号：US12609641
申请日：2009-10-30
CPC分类号： A61M27/006 , A61M2202/0464 , A61M2205/3515 , F16K31/08 , F16K37/0041 , Y10T137/7878 , Y10T137/8242
摘要： Integrated tools for noninvasively reading and adjusting an implantable, magnetically adjustable valve, and methods of use are disclosed. The tools include magnetic or electronic reading of the valve, and magnetic or electromagnetic adjustment of the valve. In use, the tools are positioned above or in contact with the patient's skin, in proximity to the valve.
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公开(公告)号：US20120165794A1
公开(公告)日：2012-06-28
申请号：US12976761
申请日：2010-12-22
申请人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
发明人： Mark S. Ortiz , Christopher J. Hess , Jason L. Harris , James W. Voegele , Mark S. Zeiner , Mark D. Overmyer , Joseph B. Kraimer , Jeff Shimizu , Rocco Crivelli , Yanik Tardy , Thierry Utard , Juergen Burger , Toralf Bork , Martin Pfleiderer , Olivier Chossat
IPC分类号： A61M31/00
CPC分类号： A61B1/041 , A61B1/00147 , A61F5/0013 , A61M31/002
摘要： Devices and related methods are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, methods and devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as “catchers,” are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.
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公开(公告)号：US20090198280A1
公开(公告)日：2009-08-06
申请号：US12257404
申请日：2008-10-24
申请人： Frank Spratt , Martin Pfleiderer
发明人： Frank Spratt , Martin Pfleiderer
CPC分类号： A61B17/7037 , A61B17/701 , A61B17/7032 , A61B17/7038
摘要： An assembly for connecting a support element to a bone. The assembly comprises: a bone screw having a head at one end of a threaded shaft; and a clamp comprising: a base at a first end of the clamp delimiting an opening for receiving the head of the bone screw; and at least two side members extending from the base towards a second end of the clamp. The head of the bone screw and the clamp are configured to allow the head of the bone screw to be inserted into the base from the direction of the first end at a first orientation of the base to the bone screw, and to retain an inserted bone screw within the base at a second orientation of the base relative to the bone screw.This allows the screw to be inserted into the bone without requiring prior assembly of the screw and clamp. It also allows later revision whereby the clamp can be removed from the screw without requiring an implanted screw to be removed from the bone.
摘要翻译： 用于将支撑元件连接到骨骼的组件。 组件包括：骨螺钉，其在螺纹轴的一端具有头部; 以及夹具，其包括：在所述夹具的第一端处的基部，其限定用于接收所述骨螺钉的头部的开口; 以及至少两个侧部构件，其从所述底座延伸到所述夹具的第二端。 骨螺钉和夹具的头部构造成允许骨螺钉的头部在基部的第一方位到骨螺钉处从第一端的方向插入到基部中，并且保持插入的骨 在底座内以相对于骨螺钉的第二方位在螺钉内螺旋。 这样可以将螺钉插入到骨骼中，而无需事先组装螺丝和夹具。 它还允许稍后的修改，由此可以从螺钉移除夹具，而不需要从骨头移除植入的螺钉。
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公开(公告)号：US20150045850A1
公开(公告)日：2015-02-12
申请号：US13825459
申请日：2012-03-30
申请人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo
发明人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D' Arcangelo
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device (11) which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device (11) such that the stimulus device (11) applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译： 用于刺激受试者中的饱腹感激素的释放的可植入系统包括刺激装置（11），其可植入对象中并适于对所述受试者的胃肠系统的组织施加电刺激，以及检测装置 可植入在受试者中并且适于连续地监测受试者的机械特性和电特性中的至少一个以检测所述受试者摄入的食物，其中检测装置与刺激装置（11）配合使得刺激装置 （11）响应于检测到的食物摄入而应用所述电刺激。
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公开(公告)号：US08430914B2
公开(公告)日：2013-04-30
申请号：US12257404
申请日：2008-10-24
申请人： Frank Spratt , Martin Pfleiderer
发明人： Frank Spratt , Martin Pfleiderer
IPC分类号： A61B17/70
CPC分类号： A61B17/7037 , A61B17/701 , A61B17/7032 , A61B17/7038
摘要： An assembly for connecting a support element to a bone. The assembly comprises: a bone screw having a head at one end of a threaded shaft; and a clamp comprising: a base at a first end of the clamp delimiting an opening for receiving the head of the bone screw; and at least two side members extending from the base towards a second end of the clamp. The head of the bone screw and the clamp are configured to allow the head of the bone screw to be inserted into the base from the direction of the first end at a first orientation of the base to the bone screw, and to retain an inserted bone screw within the base at a second orientation of the base relative to the bone screw.This allows the screw to be inserted into the bone without requiring prior assembly of the screw and clamp. It also allows later revision whereby the clamp can be removed from the screw without requiring an implanted screw to be removed from the bone.
摘要翻译： 用于将支撑元件连接到骨骼的组件。 组件包括：骨螺钉，其在螺纹轴的一端具有头部; 以及夹具，其包括：在所述夹具的第一端处的基部，其限定用于接收所述骨螺钉的头部的开口; 以及至少两个侧部构件，其从所述底座延伸到所述夹具的第二端。 骨螺钉和夹具的头部构造成允许骨螺钉的头部在基部的第一方位到骨螺钉处从第一端的方向插入到基部中，并且保持插入的骨 在底座内以相对于骨螺钉的第二方位在螺钉内螺旋。 这样可以将螺钉插入到骨骼中，而无需事先组装螺丝和夹具。 它还允许稍后的修改，由此可以从螺钉移除夹具，而不需要从骨头移除植入的螺钉。
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公开(公告)号：US09427580B2
公开(公告)日：2016-08-30
申请号：US13825459
申请日：2012-03-30
申请人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D'Arcangelo
发明人： Toralf Bork , Rocco Crivelli , Mathilde Miguras , Martin Pfleiderer , Yanik Tardy , Jason L. Harris , Mark S. Ortiz , Alessandro Pastorelli , Michele D'Arcangelo
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device such that the stimulus device applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译： 用于刺激受试者中的饱腹感激素的释放的可植入系统包括刺激装置，该刺激装置可植入受试者并适于对所述受试者的胃肠系统的组织施加电刺激，以及可植入在所述受试者中的检测装置 受试者并且适于连续监测受试者的机械特征和电特性中的至少一个以检测所述受试者摄取食物，其中所述检测装置与刺激装置配合使得刺激装置应答所述电刺激 检测到摄入食物。
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公开(公告)号：US20110105991A1
公开(公告)日：2011-05-05
申请号：US12609641
申请日：2009-10-30
CPC分类号： A61M27/006 , A61M2202/0464 , A61M2205/3515 , F16K31/08 , F16K37/0041 , Y10T137/7878 , Y10T137/8242
摘要： Integrated tools for noninvasively reading and adjusting an implantable, magnetically adjustable valve, and methods of use are disclosed. The tools include magnetic or electronic reading of the valve, and magnetic or electromagnetic adjustment of the valve. In use, the tools are positioned above or in contact with the patient's skin, in proximity to the valve.
摘要翻译： 公开了用于非侵入性读取和调节可植入的磁力可调节阀的集成工具和使用方法。 这些工具包括阀门的磁性或电子读数，以及阀门的磁性或电磁调节。 在使用中，工具位于患者皮肤的上方或与其接触的位置。
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公开(公告)号：US20060111727A1
公开(公告)日：2006-05-25
申请号：US10527149
申请日：2003-09-16
申请人： Martin Pfleiderer , Alec Birkbeck
发明人： Martin Pfleiderer , Alec Birkbeck
CPC分类号： A61F2/4611 , A61F2002/30092 , A61F2002/4627 , A61F2210/0014
摘要： A device (10) for delivering a surgical implant (14) comprises a guide track (11) for guiding the movement of a spinal implant (14) to an implantation site. An implant carrier (12) engages the implant in the guide track and can move along the guide track in order to deliver the implant to the implantation site, the carrier (12) including a connector (15) which can be displaced between a connected position in which the implant is connected to the carrier to move with it in the guide track, and a disconnected position in which the implant can be separated from the carrier. A driving device (13) can engage the implant carrier to move the carrier (12) along the track. A formation can cause the connector (15) on the implant carrier (12) to be displaced from the connected to the disconnected position when the carrier reaches a pre-determined position.
摘要翻译： 用于输送外科植入物（14）的装置（10）包括用于将脊柱植入物（14）的运动引导到植入部位的导轨（11）。 植入物载体（12）将植入物接合在导轨中并且可以沿着导轨移动，以将植入物输送到植入位置，载体（12）包括连接器（15），该连接器可以在连接位置 其中植入物连接到载体以与导轨一起移动，以及其中植入物可以与载体分离的断开位置。 驱动装置（13）可以接合植入物载体以沿着轨道移动载体（12）。 当载体到达预定位置时，地层可以导致植入载体（12）上的连接器（15）从连接到断开位置移位。
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