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公开(公告)号：US20100314538A1
公开(公告)日：2010-12-16
申请号：US12521688
申请日：2007-12-27
CPC分类号： H01J49/009 , H01J49/425
摘要： A system and method of mass spectrometry is provided. Ions from an ion source are stored in a first ion storage device and in a second ion storage device. Ions are ejected from the first ion storage device to a first mass analysis device during a first ejection time period, for analysis during a first analysis time period. Ions are ejected from the second ion storage device to a second mass analysis device during a second ejection time period. The ion storage devices are connected in series such that an ion transport aperture of the first ion storage device is in communication with an ion transport aperture of the second ion storage device. The first analysis time period and the second ejection time period at least partly overlap.
摘要翻译： 提供了一种质谱系统和方法。 来自离子源的离子存储在第一离子存储装置和第二离子存储装置中。 在第一喷射时间段期间，离子从第一离子存储装置喷射到第一质量分析装置，以在第一分析时间段期间进行分析。 在第二喷射时间段期间，离子从第二离子存储装置喷射到第二质量分析装置。 离子存储装置串联连接，使得第一离子存储装置的离子传送孔与第二离子存储装置的离子传送孔连通。 第一分析时间段和第二喷射时间段至少部分重叠。
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公开(公告)号：US07985950B2
公开(公告)日：2011-07-26
申请号：US12521688
申请日：2007-12-27
CPC分类号： H01J49/009 , H01J49/425
摘要： A system and method of mass spectrometry is provided. Ions from an ion source are stored in a first ion storage device and in a second ion storage device. Ions are ejected from the first ion storage device to a first mass analysis device during a first ejection time period, for analysis during a first analysis time period. Ions are ejected from the second ion storage device to a second mass analysis device during a second ejection time period. The ion storage devices are connected in series such that an ion transport aperture of the first ion storage device is in communication with an ion transport aperture of the second ion storage device. The first analysis time period and the second ejection time period at least partly overlap.
摘要翻译： 提供了一种质谱系统和方法。 来自离子源的离子存储在第一离子存储装置和第二离子存储装置中。 在第一喷射时间段期间，离子从第一离子存储装置喷射到第一质量分析装置，以在第一分析时间段期间进行分析。 在第二喷射时间段期间，离子从第二离子存储装置喷射到第二质量分析装置。 离子存储装置串联连接，使得第一离子存储装置的离子传送孔与第二离子存储装置的离子传送孔连通。 第一分析时间段和第二喷射时间段至少部分重叠。
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公开(公告)号：US08513595B2
公开(公告)日：2013-08-20
申请号：US13164693
申请日：2011-06-20
CPC分类号： H01J49/009 , H01J49/425
摘要： A system and method of mass spectrometry is provided. Ions from an ion source are stored in a first ion storage device and in a second ion storage device. Ions are ejected from the first ion storage device to a first mass analysis device during a first ejection time period, for analysis during a first analysis time period. Ions are ejected from the second ion storage device to a second mass analysis device during a second ejection time period. The ion storage devices are connected in series such that an ion transport aperture of the first ion storage device is in communication with an ion transport aperture of the second ion storage device. The first analysis time period and the second ejection time period at least partly overlap.
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公开(公告)号：US20070203652A1
公开(公告)日：2007-08-30
申请号：US10592745
申请日：2005-03-24
申请人： Stevan Horning , Oliver Lange , Robert Malek , Andreas Wieghaus
发明人： Stevan Horning , Oliver Lange , Robert Malek , Andreas Wieghaus
IPC分类号： G06F19/00
CPC分类号： H01J49/38 , H01J49/0009
摘要： The present invention provides a method of improving a mass spectrum collected from a mass spectrometer comprising a detector for collecting a mass spectrum from ions stored in or released from an ion trapping volume, wherein assignment of masses to peaks appearing in the mass spectrum is sensitive to an experimental parameter related to the mass spectrometer or the operation thereof, such as ion abundance, the method comprising: determining a positional value of a peak; determining the experimental parameter associated with the mass spectrum; comparing the determined positional value with positional values of peaks contained in a calibration dataset; and improving the determined positional value of the peak from adjacent peak positional values by interpolation thereby to provide a corrected mass assignment for the peak. The present invention also provides a method of calibrating such a mass spectrometer.
摘要翻译： 本发明提供了一种改进从质谱仪收集的质谱的方法，该质谱仪包括用于从离子捕获体积存储或释放的离子中收集质谱的检测器，其中质谱对质谱中出现的峰的分配对 与质谱仪或其操作相关的实验参数，例如离子丰度，该方法包括：确定峰的位置值; 确定与质谱相关的实验参数; 将确定的位置值与校准数据集中包含的峰的位置值进行比较; 并且通过插值从相邻的峰值位置值改善确定的峰值的位置值，从而为峰值提供校正的质量分配。 本发明还提供了一种校准这种质谱仪的方法。
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公开(公告)号：US07576318B2
公开(公告)日：2009-08-18
申请号：US10573394
申请日：2004-09-24
申请人： Robert Malek , Oliver Lange , Reinhold Pesch , Stevan Horning
发明人： Robert Malek , Oliver Lange , Reinhold Pesch , Stevan Horning
CPC分类号： H01J49/0027
摘要： The present invention relates to mass spectrometry and, more particularly, to the scheduling of the steps involved in performing mass spectrometry. The present invention will be of particular benefit to types of mass spectrometry that generate large quantities of data and hence give rise to lengthy data-processing. The present invention provides a method of mass spectrometry comprising a plurality of cycles, each cycle comprising the steps of (a) preparing ions to be analysed by a mass spectrometer; (b) using a detector of the mass spectrometer to collect data from the ions prepared in step (a); and (c) processing the data collected in step (b) with processing means; wherein at least a part of step (a) and/or a part of step (b) of a cycle is performed concurrently with part (c) of a previous cycle.
摘要翻译： 本发明涉及质谱，更具体地，涉及执行质谱法所涉及步骤的调度。 本发明对于产生大量数据的质谱的类型特别有益，因此引起冗长的数据处理。 本发明提供一种包含多个循环的质谱方法，每个循环包括以下步骤：（a）制备待通过质谱仪分析的离子; （b）使用质谱仪的检测器从步骤（a）中制备的离子收集数据; 和（c）用处理装置处理在步骤（b）中收集的数据; 其中与先前循环的部分（c）同时执行循环的步骤（a）和/或步骤（b）的一部分的至少一部分。
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公开(公告)号：US20070023630A1
公开(公告)日：2007-02-01
申请号：US10573394
申请日：2004-09-24
申请人： Robert Malek , Oliver Lange , Reinhold Pesch , Stevan Horning
发明人： Robert Malek , Oliver Lange , Reinhold Pesch , Stevan Horning
CPC分类号： H01J49/0027
摘要： The present invention relates to mass spectrometry and, more particularly, to the scheduling of the steps involved in performing mass spectrometry. The present invention will be of particular benefit to types of mass spectrometry that generate large quantities of data and hence give rise to lengthy data-processing. The present invention provides a method of mass spectrometry comprising a plurality of cycles, each cycle comprising the steps of (a) preparing ions to be analysed by a mass spectrometer; (b) using a detector of the mass spectrometer to collect data from the ions prepared in step (a); and (c) processing the data collected in step (b) with processing means; wherein at least a part of step (a) and/or a part of step (b) of a cycle is performed concurrently with part (c) of a previous cycle.
摘要翻译： 本发明涉及质谱，更具体地，涉及执行质谱法所涉及步骤的调度。 本发明对于产生大量数据的质谱的类型特别有益，因此引起冗长的数据处理。 本发明提供一种包含多个循环的质谱方法，每个循环包括以下步骤：（a）制备待通过质谱仪分析的离子; （b）使用质谱仪的检测器从步骤（a）中制备的离子收集数据; 和（c）用处理装置处理在步骤（b）中收集的数据; 其中与先前循环的部分（c）同时执行循环的步骤（a）和/或步骤（b）的一部分的至少一部分。
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公开(公告)号：US06987261B2
公开(公告)日：2006-01-17
申请号：US10763401
申请日：2004-01-23
IPC分类号： H01J49/00
CPC分类号： H01J49/4265
摘要： Method and apparatus of controlling an ion population to be analyzed in a mass analyzer. Ions are accumulated for an injection time interval determined as a function of an ion accumulation rate and a predetermined desired population of ions. The accumulation rate represents a flow rate of ions from a source of ions into an ion accumulator. Ions derived from the accumulated ions are introduced into the mass analyzer for analysis.
摘要翻译： 控制在质量分析仪中分析离子群体的方法和装置。 以作为离子累积速率和预定的期望离子群的函数确定的注入时间间隔累积离子。 累积速率表示离子从离子源到离子蓄能器的流速。 从积聚的离子得到的离子被引入质量分析器进行分析。
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