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    RAMAN SPECTROSCOPY LIGHT AMPLIFYING STRUCTURE
    1.
    发明申请
    RAMAN SPECTROSCOPY LIGHT AMPLIFYING STRUCTURE 审中-公开
    拉曼光谱放大结构

    公开(公告)号：US20120200851A1

    公开(公告)日：2012-08-09

    申请号：US13384866

    申请日：2009-10-23

    申请人： Wei Wu ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski

    发明人： Wei Wu ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski

    IPC分类号： G01J3/44

    CPC分类号： G01N21/658

    摘要： A light amplifying structure 100 for Raman spectroscopy includes a a resonant cavity 108. A distance between a first portion 102B and a second portion 102A of the structure 100 forming the resonant cavity 108 is used to amplify excitation light emitted from a light source 420 into the resonant cavity 108 at a first resonant frequency of the resonant cavity 108. Also, the resonant cavity 108 amplifies radiated light radiated from a predetermined molecule excited by the excitation light in the resonant cavity at a second resonant frequency of the resonant cavity 108.

    摘要翻译： 用于拉曼光谱的光放大结构100包括谐振腔108.第一部分102B和形成谐振腔108的结构100的第二部分102A之间的距离用于将从光源420发射的激发光放大到谐振腔 谐振腔108在谐振腔108的第二谐振频率处放大从由谐振腔中的激发光激发的预定分子辐射的辐射光。

    Molecule detection using Raman light detection
    2.
    发明授权
    Molecule detection using Raman light detection 失效
    使用拉曼光检测的分子检测

    公开(公告)号：US08208137B2

    公开(公告)日：2012-06-26

    申请号：US12696853

    申请日：2010-01-29

    申请人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    发明人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44

    摘要： An apparatus for detecting at least one molecule using Raman light detection includes a substrate for supporting a sample containing the at least one molecule, a laser source for emitting a laser beam to cause Raman light emission from the at least one molecule, a modulating element for modulating a spatial relationship between the laser beam and the substrate at an identified frequency to cause the Raman light to be emitted from the at least one molecule at the identified frequency, at least one detector for detecting the Raman light emitted from the at least one molecule, and a post-signal processing unit configured to process the detected Raman light emission at the identified frequency to detect the at least one molecule.

    摘要翻译： 用于使用拉曼光检测检测至少一个分子的装置包括用于支撑含有至少一个分子的样品的基底，用于发射激光束以产生来自至少一个分子的拉曼光发射的激光源， 以识别的频率调制激光束和衬底之间的空间关系，以使所述拉曼光以所识别的频率从所述至少一个分子发射;至少一个检测器，用于检测从所述至少一个分子发射的拉曼光 以及后信号处理单元，被配置为处理所识别的频率处的所检测的拉曼光发射以检测所述至少一个分子。

    SURFACE ENHANCED RAMAN SPECTROSCOPY EMPLOYING VIBRATING NANORODS
    3.
    发明申请
    SURFACE ENHANCED RAMAN SPECTROSCOPY EMPLOYING VIBRATING NANORODS 有权
    表面增强拉曼光谱仪采用振动纳米级

    公开(公告)号：US20110188034A1

    公开(公告)日：2011-08-04

    申请号：US12697136

    申请日：2010-01-29

    申请人： Michael J. Stuke ,  Alexandre M. Bratkovski ,  Min Hu ,  Huei Pei Kuo ,  Jingjing Li ,  Zhiyong Li ,  Fung Suong Ou ,  Shih-Yuan (Sy) Wang ,  Wei Wu

    发明人： Michael J. Stuke ,  Alexandre M. Bratkovski ,  Min Hu ,  Huei Pei Kuo ,  Jingjing Li ,  Zhiyong Li ,  Fung Suong Ou ,  Shih-Yuan (Sy) Wang ,  Wei Wu

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44 ,  G01N21/658

    摘要： A surface enhanced Raman spectroscopy (SERS) apparatus, system and method employ a plurality of nanorods configured to vibrate. The apparatus includes the nanorods having tips at free ends opposite an end attached to a substrate. The tips are configured to adsorb an analyte and to vibrate at a vibration frequency. The apparatus further includes a vibration source configured to vibrate the free ends of the nanorods at the vibration frequency in a back-and-forth motion. Vibration of the nanorods is configured to facilitate detection of a Raman scattering signal emitted by the analyte adsorbed on the nanorod tips. The system further includes a synchronous detector configured to receive the Raman signal and to be gated cooperatively with the vibration of the nanorods. The method includes inducing a vibration of the nanorods, illuminating the vibrating tips to produce a Raman signal, and detecting the Raman signal using the detector.

    摘要翻译： 表面增强拉曼光谱（SERS）装置，系统和方法采用配置成振动的多个纳米棒。 该装置包括纳米棒，其具有与连接到基底的端部相对的自由端处的尖端。 尖端被配置为吸附分析物并以振动频率振动。 该装置还包括一个振动源，其构造成以往复运动的振动频率使纳米棒的自由端振动。 纳米棒的振动被配置为便于检测由吸附在纳米棒尖端上的分析物发射的拉曼散射信号。 该系统还包括一个同步检测器，其被配置为接收拉曼信号并与纳米棒的振动协同地门控。 该方法包括诱导纳米棒的振动，照亮振动尖端以产生拉曼信号，以及使用检测器检测拉曼信号。

    VIBRATING TIP SURFACE ENHANCED RAMAN SPECTROSCOPY
    5.
    发明申请
    VIBRATING TIP SURFACE ENHANCED RAMAN SPECTROSCOPY 有权
    振动提示表面增强拉曼光谱

    公开(公告)号：US20110188035A1

    公开(公告)日：2011-08-04

    申请号：US12697156

    申请日：2010-01-29

    申请人： Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

    发明人： Huei Pei Kuo ,  Michael J. Stuke ,  Min Hu ,  Fung Suong Ou ,  Shih-Yuan (SY) Wang ,  Alexandre M. Bratkovski ,  Wei Wu ,  Zhiyong Li

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44

    摘要： A vibrating tip surface enhanced Raman spectroscopy (SERS) apparatus, system and method employ a nano-needle configured to vibrate. The apparatus includes the nano-needle with a substantially sharp tip at a free end opposite an end attached to a substrate. The tip is configured to adsorb an analyte. The apparatus further includes a vibration source configured to provide an alternating current (AC) electric field that induces a vibration of the free end and the tip of the nano-needle. Vibration of the nano-needle under the influence of the AC electric field facilitates detection of a Raman scattering signal from the analyte adsorbed on the nano-needle tip. The system further includes a synchronous detector configured to be gated cooperatively with the vibration of the nano-needle. The method includes inducing the vibration, illuminating the vibrating tip to produce a Raman signal, and detecting the Raman signal using the detector.

    摘要翻译： 振动尖端表面增强拉曼光谱（SERS）装置，系统和方法采用配置为振动的纳米针。 该装置包括在与连接到基底的端相对的自由端处具有基本尖锐的尖端的纳米针。 尖端构造成吸附分析物。 该装置还包括一个被配置为提供交流（AC）电场的振动源，其引起自由端和纳米针的尖端的振动。 在AC电场的影响下，纳米针的振动有助于检测吸附在纳米针尖上的分析物的拉曼散射信号。 该系统还包括配置为与纳米针的振动协同地选通的同步检测器。 该方法包括引起振动，照亮振动尖端以产生拉曼信号，并使用检测器检测拉曼信号。

    Reconfigurable surface enhanced Raman spectroscopy apparatus, system and method
    7.
    发明授权
    Reconfigurable surface enhanced Raman spectroscopy apparatus, system and method 有权
    可重构表面增强拉曼光谱仪，系统和方法

    公开(公告)号：US08477303B2

    公开(公告)日：2013-07-02

    申请号：US13014688

    申请日：2011-01-26

    申请人： Alexandre M Bratkovski ,  Wei Wu ,  Zhiyong Li

    发明人： Alexandre M Bratkovski ,  Wei Wu ,  Zhiyong Li

    IPC分类号： G01J3/44

    CPC分类号： G01N21/658 ,  B82Y20/00

    摘要： A reconfigurable surface enhanced Raman spectroscopy (SERS) apparatus, system and method employ a stimulus responsive material to move nanorods of a plurality between inactive and active configurations. The apparatus includes the plurality of nanorods and the stimulus responsive material. The system further includes a Raman signal detector. The method of reconfigurable SERS includes providing the plurality of nanorods and exposing the stimulus responsive material to a stimulus. The exposure causes a change in one or more of a size, a shape and a volume of the stimulus responsive material that moves the nanorods between the inactive and active configurations. The active configuration facilitates one or both of production and detection of a Raman scattering signal emitted by the analyte.

    摘要翻译： 可重新配置的表面增强拉曼光谱（SERS）装置，系统和方法使用刺激响应材料来移动多个非活动和活动配置之间的纳米棒。 该装置包括多个纳米棒和刺激响应材料。 该系统还包括拉曼信号检测器。 可重新配置的SERS的方法包括提供多个纳米棒并将刺激响应材料暴露于刺激。 暴露导致在非活性和活动配置之间移动纳米棒的刺激响应材料的尺寸，形状和体积中的一种或多种的变化。 活性配置有利于分析物发射的拉曼散射信号的生成和检测中的一个或两个。

    Surface enhanced Raman spectroscopy employing vibrating nanorods
    8.
    发明授权
    Surface enhanced Raman spectroscopy employing vibrating nanorods 有权
    使用振动纳米棒的表面增强拉曼光谱

    公开(公告)号：US08390804B2

    公开(公告)日：2013-03-05

    申请号：US12697136

    申请日：2010-01-29

    申请人： Michael J. Stuke ,  Alexandre M. Bratkovski ,  Min Hu ,  Huei Pei Kuo ,  Jingjing Li ,  Zhiyong Li ,  Fung Suong Ou ,  Shih-Yuan (Sy) Wang ,  Wei Wu

    发明人： Michael J. Stuke ,  Alexandre M. Bratkovski ,  Min Hu ,  Huei Pei Kuo ,  Jingjing Li ,  Zhiyong Li ,  Fung Suong Ou ,  Shih-Yuan (Sy) Wang ,  Wei Wu

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44 ,  G01N21/658

    摘要： A surface enhanced Raman spectroscopy (SERS) apparatus, system and method employ a plurality of nanorods configured to vibrate. The apparatus includes the nanorods having tips at free ends opposite an end attached to a substrate. The tips are configured to adsorb an analyte and to vibrate at a vibration frequency. The apparatus further includes a vibration source configured to vibrate the free ends of the nanorods at the vibration frequency in a back-and-forth motion. Vibration of the nanorods is configured to facilitate detection of a Raman scattering signal emitted by the analyte adsorbed on the nanorod tips. The system further includes a synchronous detector configured to receive the Raman signal and to be gated cooperatively with the vibration of the nanorods. The method includes inducing a vibration of the nanorods, illuminating the vibrating tips to produce a Raman signal, and detecting the Raman signal using the detector.

    摘要翻译： 表面增强拉曼光谱（SERS）装置，系统和方法采用配置成振动的多个纳米棒。 该装置包括纳米棒，其具有与连接到基底的端部相对的自由端处的尖端。 尖端被配置为吸附分析物并以振动频率振动。 该装置还包括一个振动源，其构造成以往复运动的振动频率使纳米棒的自由端振动。 纳米棒的振动被配置为便于检测由吸附在纳米棒尖端上的分析物发射的拉曼散射信号。 该系统还包括一个同步检测器，其被配置为接收拉曼信号并与纳米棒的振动协同地门控。 该方法包括诱导纳米棒的振动，照亮振动尖端以产生拉曼信号，以及使用检测器检测拉曼信号。

    MOLECULE DETECTION USING RAMAN LIGHT DETECTION
    10.
    发明申请
    MOLECULE DETECTION USING RAMAN LIGHT DETECTION 失效
    使用拉曼光检测的分子检测

    公开(公告)号：US20110188033A1

    公开(公告)日：2011-08-04

    申请号：US12696853

    申请日：2010-01-29

    申请人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    发明人： Min Hu ,  Alexandre M. Bratkovski ,  Jingjing Li ,  Huei Pei Kuo ,  Zhiyong Li ,  Fung Suong Ou ,  Michael Josef Stuke ,  Michael Renne Ty Tan ,  Shih-Yuan Wang ,  Wei Wu

    IPC分类号： G01J3/44

    CPC分类号： G01J3/44

    摘要： An apparatus for detecting at least one molecule using Raman light detection includes a substrate for supporting a sample containing the at least one molecule, a laser source for emitting a laser beam to cause Raman light emission from the at least one molecule, a modulating element for modulating a spatial relationship between the laser beam and the substrate at an identified frequency to cause the Raman light to be emitted from the at least one molecule at the identified frequency, at least one detector for detecting the Raman light emitted from the at least one molecule, and a post-signal processing unit configured to process the detected Raman light emission at the identified frequency to detect the at least one molecule.

    摘要翻译： 用于使用拉曼光检测检测至少一个分子的装置包括用于支撑含有至少一个分子的样品的基底，用于发射激光束以产生来自至少一个分子的拉曼光发射的激光源， 以识别的频率调制激光束和衬底之间的空间关系，以使所述拉曼光以所识别的频率从所述至少一个分子发射;至少一个检测器，用于检测从所述至少一个分子发射的拉曼光 以及后信号处理单元，被配置为处理所识别的频率处的所检测的拉曼光发射以检测所述至少一个分子。