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公开(公告)号：US20130100456A1
公开(公告)日：2013-04-25
申请号：US13444410
申请日：2012-04-11
IPC分类号： G01B9/02
CPC分类号： G01B9/02091 , A61B3/102 , G01B9/02004 , G01B9/02011 , G01B9/02014 , G01B9/02082 , G01B2290/70 , H01S3/07 , H01S3/08054 , H01S3/0809 , H01S3/0823 , H01S3/105 , H01S5/141
摘要： Systems and methods for increasing the duty cycle and/or producing interleaved pulses of alternating polarization states in swept-source optical coherence tomography (OCT) systems are considered. Embodiments including improved buffering, frequency selecting filter sharing among multiple SOAs, intracavity switching, and multiple wavelength bands are described. The unique polarization properties of the source configurations have advantages in speckle reduction, polarization-sensitive measurements, polarization state dependent phase shifts, spatial shifts, and temporal shifts in OCT measurements.
摘要翻译： 考虑在扫描光源相干断层摄影（OCT）系统中用于增加占空比和/或产生交替偏振状态的交错脉冲的系统和方法。 描述了包括改进的缓冲，多个SOA中的频率选择滤波器共享，腔内切换和多个波长带的实施例。 源结构的独特偏振特性在斑点减少，偏振敏感测量，极化状态相关相移，空间位移和OCT测量中的时间偏移方面具有优势。
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公开(公告)号：US08998411B2
公开(公告)日：2015-04-07
申请号：US13542516
申请日：2012-07-05
摘要： Systems and methods for applying the concept of lightfield sensors to fundus photography are presented. In one embodiment, the ability to isolate specific regions of the collected lightfield are used to reduce the effects of glare in a fundus image. Additional embodiments in which aberrations can be characterized and removed, an image from a particular plane in the collected light field is used to aid in instrument alignment, and dynamic optimization of collection pupil diameter is accomplished are also presented.
摘要翻译： 介绍了将光场传感器应用于眼底摄影的系统和方法。 在一个实施例中，使用分离所收集的光场的特定区域的能力来减少眼底图像中眩光的影响。 其中可以表征和去除像差的其他实施例，来自收集的光场中的特定平面的图像用于帮助仪器对准，并且还呈现收集光瞳直径的动态优化。
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3.发明授权Systems and methods for improved balanced detection in optical coherence tomography imaging 有权用于改善光学相干层析成像中平衡检测的系统和方法公开(公告)号：US08913248B2
公开(公告)日：2014-12-16
申请号：US13489368
申请日：2012-06-05
CPC分类号： A61B5/0066 , A61B3/102 , G01B9/02004 , G01B9/02058 , G01B9/0207 , G01B9/02091
摘要： Systems and methods for reducing noise in balanced detection based optical coherence tomography (OCT) systems are described. Embodiments including both optical hardware and electronic based solutions to spectrally filter and attenuate the source reference light in optical coherence tomography in an effort to reduce RIN and FPN noise in OCT systems are presented. A novel application to electronic balanced detection schemes in which a single source of reference detection is balanced against the interferometric signals from multiple interferometers is also presented.
摘要翻译： 描述了基于平衡检测的光学相干断层扫描（OCT）系统中降低噪声的系统和方法。 提出了包括光学硬件和基于电子的解决方案的实施例，以在光学相干断层摄影中频谱滤波和衰减源参考光，以努力降低OCT系统中的RIN和FPN噪声。 还提出了一种电子平衡检测方案的新颖应用，其中单个参考检测源与来自多个干涉仪的干涉信号平衡。
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4.发明申请SYSTEMS AND METHODS FOR IMPROVED BALANCED DETECTION IN OPTICAL COHERENCE TOMOGRAPHY IMAGING 有权用于光学相干图像成像中改进的平衡检测的系统和方法公开(公告)号：US20130010302A1
公开(公告)日：2013-01-10
申请号：US13489368
申请日：2012-06-05
IPC分类号： G01B9/02
CPC分类号： A61B5/0066 , A61B3/102 , G01B9/02004 , G01B9/02058 , G01B9/0207 , G01B9/02091
摘要： Systems and methods for reducing noise in balanced detection based optical coherence tomography (OCT) systems are described. Embodiments including both optical hardware and electronic based solutions to spectrally filter and attenuate the source reference light in optical coherence tomography in an effort to reduce RIN and FPN noise in OCT systems are presented. A novel application to electronic balanced detection schemes in which a single source of reference detection is balanced against the interferometric signals from multiple interferometers is also presented.
摘要翻译： 描述了基于平衡检测的光学相干断层扫描（OCT）系统中降低噪声的系统和方法。 提出了包括光学硬件和基于电子的解决方案的实施例，以在光学相干断层摄影中频谱滤波和衰减源参考光，以努力降低OCT系统中的RIN和FPN噪声。 还提出了一种电子平衡检测方案的新颖应用，其中单个参考检测源与来自多个干涉仪的干涉信号平衡。
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公开(公告)号：US08817269B2
公开(公告)日：2014-08-26
申请号：US13457297
申请日：2012-04-26
IPC分类号： G01B9/02
CPC分类号： G01B9/02058 , A61B3/102 , G01B9/02057 , G01B9/02091 , G01B2290/30
摘要： An improved interferometer measurement system is presented. In a preferred embodiment, a chirped fiber Bragg grating is used as a reference surface in a Fizeau interferometer arrangement for optical coherence tomography imaging of the eye. The grating creates a virtual reference surface near the sample and allows for a relatively short reference arm while maintaining close to zero delay interference conditions.
摘要翻译： 提出了一种改进的干涉仪测量系统。 在优选实施例中，啁啾光纤布拉格光栅用作用于眼睛的光学相干断层成像的Fizeau干涉仪布置中的参考表面。 光栅在样品附近创建一个虚拟参考表面，并允许相对较短的参考臂，同时保持接近零的延迟干扰条件。
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公开(公告)号：US20080228033A1
公开(公告)日：2008-09-18
申请号：US11994713
申请日：2006-06-30
IPC分类号： A61B1/04
CPC分类号： G02B23/2423 , A61B1/00096 , A61B1/00165 , A61B1/00172 , A61B1/00188 , A61B5/0066
摘要： Optical coherence tomograph (OCT) probe device (1) comprising an endoscope (6) which is adapted to be coupled to a light source (2) and has a distal tip portion (6.2), the tip portion (6.2) including focussing lens means (11) and a window (5) for directing light to a subject (7) to be scanned, and for receiving light scattered at the subject (7), to send the scattered light back through the endoscope (6) so that it may be applied to a detector (3) together with reference light, said OCT probe device (1) comprising a beam splitter (13; 17) to separate said reference light from the remaining light, as well as a reference light reflector (4; 20) for reflecting the reference light back so that it is composed to the light returned from the subject (7); the beam splitter (13; 17) and the reference light reflector (4; 20) are located in the tip portion (6.2) of the endoscope means (6) behind the focussing lens means (11) through which the composed light is sent back.
摘要翻译： 光学相干断层扫描仪（OCT）探针装置（1）包括适于联接到光源（2）并具有远端尖端部分（6.2）的内窥镜（6），所述尖端部分（6.2）包括聚焦透镜装置 （11）和用于将光引导到待扫描的被摄体（7）的窗口（5），并且用于接收在被摄体（7）处散射的光，以将散射的光发射回内窥镜（6），使得其可以 与参考光一起施加到检测器（3），所述OCT探针装置（1）包括分离器（13; 17）以将所述参考光与剩余的光分离，以及参考光反射器（4; 20 ），用于反射参考光，使得其与从被摄体（7）返回的光组成; 分束器（13; 17）和参考光反射器（4; 20）位于聚焦透镜装置（11）后面的内窥镜装置（6）的顶端部分（6.2）中，组合光通过该顶端部分 。
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公开(公告)号：US08908189B2
公开(公告)日：2014-12-09
申请号：US13444410
申请日：2012-04-11
CPC分类号： G01B9/02091 , A61B3/102 , G01B9/02004 , G01B9/02011 , G01B9/02014 , G01B9/02082 , G01B2290/70 , H01S3/07 , H01S3/08054 , H01S3/0809 , H01S3/0823 , H01S3/105 , H01S5/141
摘要： Systems and methods for increasing the duty cycle and/or producing interleaved pulses of alternating polarization states in swept-source optical coherence tomography (OCT) systems are considered. Embodiments including improved buffering, frequency selecting filter sharing among multiple SOAs, intracavity switching, and multiple wavelength bands are described. The unique polarization properties of the source configurations have advantages in speckle reduction, polarization-sensitive measurements, polarization state dependent phase shifts, spatial shifts, and temporal shifts in OCT measurements.
摘要翻译： 考虑在扫描光源相干断层摄影（OCT）系统中用于增加占空比和/或产生交替偏振状态的交错脉冲的系统和方法。 描述了包括改进的缓冲，多个SOA中的频率选择滤波器共享，腔内切换和多个波长带的实施例。 源结构的独特偏振特性在斑点减少，偏振敏感测量，极化状态相关相移，空间位移和OCT测量中的时间偏移方面具有优势。
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公开(公告)号：US20120274943A1
公开(公告)日：2012-11-01
申请号：US13457297
申请日：2012-04-26
IPC分类号： G01B9/02
CPC分类号： G01B9/02058 , A61B3/102 , G01B9/02057 , G01B9/02091 , G01B2290/30
摘要： An improved interferometer measurement system is presented. In a preferred embodiment, a chirped fiber Bragg grating is used as a reference surface in a Fizeau interferometer arrangement for optical coherence tomography imaging of the eye. The grating creates a virtual reference surface near the sample and allows for a relatively short reference arm while maintaining close to zero delay interference conditions.
摘要翻译： 提出了一种改进的干涉仪测量系统。 在优选实施例中，啁啾光纤布拉格光栅用作用于眼睛的光学相干断层成像的Fizeau干涉仪布置中的参考表面。 光栅在样品附近创建一个虚拟参考表面，并允许相对较短的参考臂，同时保持接近零的延迟干扰条件。
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