公开(公告)号：US3988460A

公开(公告)日：1976-10-26

申请号：US558101

申请日：1975-03-13

申请人： Alfred Rhomberg ,  Herbert Berger ,  Kurt Stach, deceased ,  by Werner Plattner, executor ,  Wolfgang Vomel ,  Winfriede Sauer

发明人： Alfred Rhomberg ,  Herbert Berger ,  Kurt Stach, deceased ,  by Werner Plattner, executor ,  Wolfgang Vomel ,  Winfriede Sauer

IPC分类号： A61K31/47

CPC分类号： A61K31/47

摘要： Certain novel cyclopentenoquinolone derivatives of the formula: ##SPC1##WhereinR and X, which may be the same or different, are hydrogen or lower saturated or unsaturated aliphatic hydrocarbyl;Y is hydroxyl or lower alkoxy or lower acyloxy (i.e., alkanoyloxy); andZ is hydrogen or lower alkoxy, or, together with Y, represents an oxo or lower alkenyldioxy radical; and the pharmacologically compatibile salts thereofAre outstandingly effective as anti-microbials, particularly for applications against infections of the urinary tract.

摘要翻译： 某些新的环戊烯喹诺酮衍生物，其结构如下：

公开(公告)号：US4087520A

公开(公告)日：1978-05-02

申请号：US665341

申请日：1976-03-09

申请人： Franz Braun ,  Kurt Stach, deceased ,  by Werner Plattner, executor ,  Max Thiel ,  Gisbert Sponer ,  Karl Dietmann

发明人： Franz Braun ,  Kurt Stach, deceased ,  by Werner Plattner, executor ,  Max Thiel ,  Gisbert Sponer ,  Karl Dietmann

IPC分类号： C07K1/113 ,  A61K38/00 ,  A61K38/05 ,  C07C67/00 ,  C07C231/00 ,  C07C231/02 ,  C07K5/06 ,  C07K5/065 ,  C07K5/083 ,  A61K37/00 ,  C07C103/52

CPC分类号： C07K5/0806 ,  C07K5/06026 ,  C07K5/06078 ,  A61K38/00 ,  Y10S530/80

摘要： An L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptide of the formula ##STR1## wherein A is an alkylene radical which can be substituted by a hydroxyl group or by a phenyl radical which optionally carries at least one hydroxyl group, andR is a hydrogen atom or a lower alkyl radical or a glycyl or alanyl radical,Or a pharmacologically compatible salt thereof. These compounds are outstanding in lowering blood pressure.

摘要翻译： 其中A是可被羟基取代的亚烷基或可任选地携带至少一个的苯基的L-3-（3,4-二羟基苯基）-2-甲基 - 丙氨酸肽 羟基，R为氢原子或低级烷基或甘氨酰或丙氨酰基，或其药理学兼容的盐。 这些化合物在降低血压方面表现突出。

公开(公告)号：US4016262A

公开(公告)日：1977-04-05

申请号：US582529

申请日：1975-05-30

申请人： Erich Fauland ,  Wolfgang Kampe ,  Kurt Stach, deceased ,  by Werner Plattner, executor ,  Harald Stork ,  Karl Dietmann

发明人： Erich Fauland ,  Wolfgang Kampe ,  Kurt Stach, deceased ,  by Werner Plattner, executor ,  Harald Stork ,  Karl Dietmann

IPC分类号： C07H19/16 ,  A61K31/70

CPC分类号： C07H19/16

摘要： N(6)-disubstituted adenosine compounds of the formula: ##STR1## wherein R.sub.1 is alkenyl, cycloalkenyl or cycloalkenyl-alkyl; andR.sub.2 is alkenyl, cycloalkenyl, straight or branched-chain alkyl, cycloalkyl, bicycloalkyl, alkyl-cycloalkyl, or alkyl-bicycloalkyl;And the pharmacologically compatible salts thereof; exhibit outstanding anti-lipolytic, anti-hyperlipaemic and anti-hypercholesterolaemic action.

摘要翻译： 具有下式的N（6） - 二取代的腺苷化合物：其中R 1是烯基，环烯基或环烯基 - 烷基; R 2为烯基，环烯基，直链或支链烷基，环烷基，二环烷基，烷基 - 环烷基或烷基 - 双环烷基; 及其药理学兼容性; 展示超耐药，抗高血压和抗高胆固醇血管作用。