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公开(公告)号：US20050020481A1
公开(公告)日：2005-01-27
申请号：US10674684
申请日：2003-09-29
申请人： Allan Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Allan Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： C07D295/08 , A61K20060101 , A61K31/13 , A61K31/133 , A61K31/135 , A61K31/40 , A61K31/4015 , A61K31/407 , A61K31/41 , A61K31/4162 , A61K31/426 , A61K31/495 , A61K31/535 , A61K31/5375 , A61K31/5377 , A61P3/10 , A61P9/00 , A61P9/02 , A61P9/04 , A61P9/06 , A61P9/10 , A61P9/12 , A61P15/00 , A61P15/10 , A61P17/14 , A61P21/00 , A61P21/04 , A61P23/00 , A61P25/00 , A61P25/06 , A61P25/28 , A61P27/02 , A61P29/00 , A61P37/06 , C07C20060101 , C07C217/52 , C07D20060101 , C07D207/04 , C07D207/12 , C07D207/24 , C07D207/26 , C07D207/27 , C07D277/04 , C07D295/096 , C07D295/15 , C07D295/18 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10 , C07D491/113 , A61K31/00
CPC分类号： C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
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公开(公告)号：US20080070911A1
公开(公告)日：2008-03-20
申请号：US11944282
申请日：2007-11-21
申请人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： A61K31/535 , A61K31/40 , C07D207/00 , C07D277/00 , C07D265/30 , A61K31/426
CPC分类号： C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
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公开(公告)号：US20050192208A2
公开(公告)日：2005-09-01
申请号：US10674684
申请日：2003-09-29
申请人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： C07D295/08 , A61K20060101 , A61K31/13 , A61K31/133 , A61K31/135 , A61K31/40 , A61K31/4015 , A61K31/407 , A61K31/41 , A61K31/4162 , A61K31/426 , A61K31/495 , A61K31/535 , A61K31/5375 , A61K31/5377 , A61P3/10 , A61P9/00 , A61P9/02 , A61P9/04 , A61P9/06 , A61P9/10 , A61P9/12 , A61P15/00 , A61P15/10 , A61P17/14 , A61P21/00 , A61P21/04 , A61P23/00 , A61P25/00 , A61P25/06 , A61P25/28 , A61P27/02 , A61P29/00 , A61P37/06 , C07C20060101 , C07C217/52 , C07D20060101 , C07D207/04 , C07D207/12 , C07D207/24 , C07D207/26 , C07D207/27 , C07D277/04 , C07D295/096 , C07D295/15 , C07D295/18 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10 , C07D491/113 , A61K31/00
CPC分类号： C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要： Abstract of the DisclosureIon channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译： 公开的摘要公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途，包括治疗心律失常和产生镇痛和局部麻醉。
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公开(公告)号：US20050209307A1
公开(公告)日：2005-09-22
申请号：US11018428
申请日：2004-12-21
申请人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： A61K31/4015 , C07D209/36
CPC分类号： A61K31/40 , A61K9/0019 , A61K31/4015 , C07D207/12 , C07D209/36
摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译： 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途，包括治疗心律失常和产生镇痛和局部麻醉。
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公开(公告)号：US20070004718A1
公开(公告)日：2007-01-04
申请号：US11450921
申请日：2006-06-09
申请人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Allen Bain , Gregory Beatch , Cindy Longley , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： A61K31/5375 , A61K31/495 , A61K31/445 , A61K31/405 , A61K31/4015 , A61K31/138
CPC分类号： C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
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公开(公告)号：US20060189677A1
公开(公告)日：2006-08-24
申请号：US11342270
申请日：2006-01-27
申请人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： A61K31/4015 , A61K9/68
CPC分类号： A61K31/40 , A61K9/0019 , A61K31/4015 , C07D207/12 , C07D209/36
摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
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公开(公告)号：US20070197632A1
公开(公告)日：2007-08-23
申请号：US11202381
申请日：2005-08-11
申请人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： A61K31/4015 , C07D207/24
CPC分类号： C07D207/08 , C07D207/10 , C07D207/12 , C07D207/20 , C07D207/24 , C07D277/04 , C07D295/096 , C07D333/56 , C07D405/12 , C07D487/12 , C07D491/10 , C07D491/113
摘要： Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
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公开(公告)号：US20070190156A1
公开(公告)日：2007-08-16
申请号：US11619136
申请日：2007-01-02
申请人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： A61K31/4015 , A61K9/14 , A61K9/48 , A61K9/68
CPC分类号： A61K31/40 , A61K9/0019 , A61K31/4015 , C07D207/12 , C07D209/36
摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译： 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途，包括治疗心律失常和产生镇痛和局部麻醉。
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公开(公告)号：US20080004333A1
公开(公告)日：2008-01-03
申请号：US11757880
申请日：2007-06-04
申请人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
CPC分类号： A61K31/40 , A61K9/0019 , A61K31/4015 , C07D209/36
摘要： Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译： 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途，包括治疗心律失常和产生镇痛和局部麻醉。
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公开(公告)号：US20060247300A1
公开(公告)日：2006-11-02
申请号：US11394388
申请日：2006-03-30
申请人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
发明人： Gregory Beatch , Bertrand Plouvier , Tao Sheng , Michael Walker , Richard Wall , Sandro Yong , Jeff Zhu , Alexander Zolotoy
IPC分类号： A61K31/4015 , C07D207/02
CPC分类号： C07D207/12 , C07D207/08 , C07D207/10 , C07D207/20 , C07D207/24 , C07D277/04 , C07D295/096 , C07D333/56 , C07D405/12 , C07D487/12 , C07D491/10 , C07D491/113
摘要： Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
摘要翻译： 公开了氨基环己基醚化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了化合物和组合物的用途，包括治疗心律失常。
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