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    METHOD AND APPARATUS FOR PACING AND INTERMITTENT ISCHEMIA
    1.
    发明申请
    METHOD AND APPARATUS FOR PACING AND INTERMITTENT ISCHEMIA 审中-公开
    方法和装置用于切割和间歇性间断

    公开(公告)号：US20090318749A1

    公开(公告)日：2009-12-24

    申请号：US12484822

    申请日：2009-06-15

    申请人： Craig Stolen ,  Allan C. Shuros ,  Shantha Arcot-Krishnamurthy ,  Eric A. Mokelke

    发明人： Craig Stolen ,  Allan C. Shuros ,  Shantha Arcot-Krishnamurthy ,  Eric A. Mokelke

    IPC分类号： A61M1/12 ,  A61N1/365

    CPC分类号： A61N1/056 ,  A61B5/02028 ,  A61B5/0215 ,  A61B5/026 ,  A61F2/95 ,  A61N1/3625 ,  A61N1/3627 ,  A61N1/36514 ,  A61N1/36564 ,  A61N1/36571

    摘要： A system delivers multiple enhanced therapies to limit myocardial damage post-revascularization. The system includes a catheter that incorporates features for delivering cardiac protection pacing therapy (CPPT) and intermittent ischemia therapy. In one embodiment, a method for delivering cardiac protection therapies to a heart is provided. One or more catheters are provided having a balloon, at least one pacing electrode and at least one hemodynamic sensor. Cardiac protection pacing therapy (CPPT) and intermittent ischemia therapy are concurrently delivered using the one or more catheters. The pacing and ischemia are adapted to protect the heart from ischemic and reperfusion injuries. The delivery of the CPPT and the intermittent ischemia are controlled using a closed-loop system monitoring a signal sensed by the at least one hemodynamic sensor.

    摘要翻译： 系统提供多种增强疗法以限制血运重建后的心肌损伤。 该系统包括导管，其包括用于递送心脏保护起搏治疗（CPPT）和间歇性缺血治疗的特征。 在一个实施方案中，提供了将心脏保护治疗递送至心脏的方法。 提供一个或多个导管，其具有球囊，至少一个起搏电极和至少一个血流动力学传感器。 使用一个或多个导管同时输送心脏保护起搏治疗（CPPT）和间歇性缺血治疗。 起搏和缺血适应于保护心脏免于缺血和再灌注损伤。 CPPT的传送和间歇性缺血通过监视由至少一个血流动力学传感器感测到的信号的闭环系统来控制。

    Method and apparatus for safe and efficient delivery of cardiac stress augmentation pacing
    2.
    发明授权
    Method and apparatus for safe and efficient delivery of cardiac stress augmentation pacing 有权
    安全高效地递送心脏应激增加起搏的方法和装置

    公开(公告)号：US08958873B2

    公开(公告)日：2015-02-17

    申请号：US12770351

    申请日：2010-04-29

    申请人： Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Craig Stolen ,  Robert Shipley

    发明人： Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Craig Stolen ,  Robert Shipley

    IPC分类号： A61N1/365 ,  A61N1/362 ,  A61N1/37

    CPC分类号： A61N1/3627 ,  A61N1/37

    摘要： A cardiac pacing system controls the progression of a cardiac disorder such as heart failure by delivering cardiac stress augmentation pacing to create or augment regional stress in the heart according to a delivery schedule programmed for a patient. Various events associated with the patient's conditions, activities, and other treatments may render the cardiac stress augmentation pacing risky or ineffective. The system detects such events before and during each cardiac stress augmentation pacing session and modifies the delivery schedule in response to the detection of each event to ensure patient safety and therapy efficiency.

    摘要翻译： 心脏起搏系统通过递送心脏应力增加起搏来控制心脏疾病例如心力衰竭的进展，以根据为患者编程的递送计划创建或增加心脏中的区域应力。 与患者病情，活动和其他治疗相关的各种事件可能使心脏应激增加起搏风险或无效。 该系统在每个心脏应激增强起搏会话之前和期间检测这些事件，并根据每个事件的检测来修改递送计划，以确保患者的安全性和治疗效率。

    METHOD AND APPARATUS FOR SAFE AND EFFICIENT DELIVERY OF CARDIAC STRESS AUGMENTATION PACING
    3.
    发明申请
    METHOD AND APPARATUS FOR SAFE AND EFFICIENT DELIVERY OF CARDIAC STRESS AUGMENTATION PACING 有权
    安全有效地提供CARDIAC应力补充剂的方法和装置

    公开(公告)号：US20100305648A1

    公开(公告)日：2010-12-02

    申请号：US12770351

    申请日：2010-04-29

    申请人： Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Craig Stolen ,  Robert Shipley

    发明人： Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Craig Stolen ,  Robert Shipley

    IPC分类号： A61N1/365 ,  A61N1/362

    CPC分类号： A61N1/3627 ,  A61N1/37

    摘要： A cardiac pacing system controls the progression of a cardiac disorder such as heart failure by delivering cardiac stress augmentation pacing to create or augment regional stress in the heart according to a delivery schedule programmed for a patient. Various events associated with the patient's conditions, activities, and other treatments may render the cardiac stress augmentation pacing risky or ineffective. The system detects such events before and during each cardiac stress augmentation pacing session and modifies the delivery schedule in response to the detection of each event to ensure patient safety and therapy efficiency.

    摘要翻译： 心脏起搏系统通过递送心脏应力增加起搏来控制心脏疾病例如心力衰竭的进展，以根据为患者编程的递送计划创建或增加心脏中的区域应力。 与患者病情，活动和其他治疗相关的各种事件可能使心脏应激增加起搏风险或无效。 该系统在每个心脏应激增强起搏会话之前和期间检测这些事件，并根据每个事件的检测来修改递送计划，以确保患者的安全性和治疗效率。

    METHOD AND APPARATUS FOR ORGAN SPECIFIC INFLAMMATION THERAPY
    5.
    发明申请
    METHOD AND APPARATUS FOR ORGAN SPECIFIC INFLAMMATION THERAPY 审中-公开
    用于组织特异性炎症治疗的方法和装置

    公开(公告)号：US20100256700A1

    公开(公告)日：2010-10-07

    申请号：US12755041

    申请日：2010-04-06

    申请人： Allan C. Shuros ,  Craig Stolen ,  Shantha Arcot-Krishnamurthy

    发明人： Allan C. Shuros ,  Craig Stolen ,  Shantha Arcot-Krishnamurthy

    IPC分类号： A61N1/365 ,  A61N1/39

    CPC分类号： A61N1/36521 ,  A61N1/3627 ,  A61N1/365 ,  A61N1/3702

    摘要： A method and device are described for delivering cardiac therapy in which an implantable device for delivering such cardiac therapy is additionally configured to detect the presence of inflammation. Upon detection of inflammation, the device may be configured to modify its delivery of therapy in various ways and/or to communicate the information to an external agent for other types of interventions.

    摘要翻译： 描述了用于递送心脏疗法的方法和装置，其中用于递送这种心脏治疗的可植入装置另外配置为检测炎症的存在。 在检测到炎症时，该装置可以被配置为以各种方式修改其治疗递送和/或将信息传达给外部代理以用于其他类型的干预。