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1.发明申请公开(公告)号：US20110085937A1
公开(公告)日：2011-04-14
申请号：US12971486
申请日：2010-12-17
IPC分类号： A61L2/10
CPC分类号： A61L12/063 , A61L2/10 , B65B25/008
摘要： This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2.This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
摘要翻译： 本发明提供了一种对医疗装置进行灭菌的方法，优选包括所述医疗装置的密封容器的内容物，其包括将所述医疗装置暴露于单色紫外线辐射的步骤，由此使嗜热脂肪芽孢杆菌（ATCC 7953）的D值至少为 在257nm处的23.7mJ / cm 2单色紫外线辐射对孢子。 此外，本发明提供一种消毒医疗装置的方法，包括以下步骤：对所述医疗装置进行单色紫外线辐射，其中到达所述医疗装置上存在的微生物的257nm处的所述单色紫外线辐射的最小总能量密度至少为 284mJ / cm 2。 本发明还提供一种用于将UV辐射递送到用于灭菌的医疗装置的装置，包括用于激光的激光器和扫描仪，使得在257nm处的至少284mJ / cm 2施加到所述医疗装置的治疗区域。 本发明提供一种方法和装置，其中可以在少于20秒，优选小于15秒，更优选在少于5秒内实现灭菌。 该方法和设备是有效和连续的。
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公开(公告)号：US06592816B1
公开(公告)日：2003-07-15
申请号：US09259796
申请日：1999-03-01
IPC分类号： A61L210
CPC分类号： A61L12/063 , A61L2/10 , B65B25/008
摘要： A sterilization system comprising: radiation source; optical and/or electrical sensors; and timing means; wherein the measurement of radiation by the optical sensor is substantially synchronized based on the timing means to the start and end of each pulse of radiation from the radiation source or to the start and end of the exposure of a product to the radiation source.
摘要翻译： 一种消毒系统，包括：辐射源; 光学和/或电传感器; 和定时手段; 其中由光学传感器辐射的测量基于从辐射源的每个辐射脉冲的开始和结束到产品暴露于辐射源的开始和结束的定时装置基本上同步。
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3.发明授权公开(公告)号：US07879288B2
公开(公告)日：2011-02-01
申请号：US10939818
申请日：2004-09-13
CPC分类号： A61L12/063 , A61L2/10 , B65B25/008
摘要： This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2.This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
摘要翻译： 本发明提供了一种对医疗装置进行灭菌的方法，优选包括所述医疗装置的密封容器的内容物，其包括将所述医疗装置暴露于单色紫外线辐射的步骤，由此使嗜热脂肪芽孢杆菌（ATCC 7953）的D值至少为 在257nm处的23.7mJ / cm 2单色紫外线辐射对孢子。 此外，本发明提供对医疗装置进行灭菌的方法，包括以下步骤：对所述医疗装置进行单色紫外线辐射，其中到达所述医疗装置上存在的微生物的257nm处的所述单色紫外线辐射的最小总能量密度至少为 284mJ / cm 2。 本发明还提供一种用于将UV辐射递送到用于灭菌的医疗装置的装置，包括用于激光的激光器和扫描仪，使得在257nm处的至少284mJ / cm 2施加到所述医疗装置的治疗区域。 本发明提供一种方法和装置，其中可以在少于20秒，优选小于15秒，更优选在少于5秒内实现灭菌。 该方法和设备是有效和连续的。
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4.发明授权公开(公告)号：US06465799B1
公开(公告)日：2002-10-15
申请号：US09515190
申请日：2000-02-29
申请人： Allan W. Kimble , John B. Enns , James A. Ebel
发明人： Allan W. Kimble , John B. Enns , James A. Ebel
IPC分类号： A61L1226
CPC分类号： A61L2/10 , A61L12/063 , B65B25/008 , G02B5/208
摘要： This invention provides a high energy radiation system which produces UV radiation comprising a selectively attenuating material which increases the ratio of desired to undesired radiation to reduce the radiation damage to a target by selectively attenuating at least 30 percent of the radiation from greater than 200 up to 240 nm which impinges upon said attenuating material, and directs greater than 50 percent of the radiation from 240 nm to 280 nm which impinges upon said attenuating material.
摘要翻译： 本发明提供了一种高能量辐射系统，其产生包括选择性衰减材料的UV辐射，其通过选择性地将至少30％的辐射从大于200直到 240nm，其照射在所述衰减材料上，并且引导大于50nm的辐射从240nm到280nm，撞击在所述衰减材料上。
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5.发明申请公开(公告)号：US20110293471A1
公开(公告)日：2011-12-01
申请号：US13208452
申请日：2011-08-12
IPC分类号： A61L2/10
CPC分类号： A61L12/063 , A61L2/10 , B65B25/008
摘要： This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2.This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
摘要翻译： 本发明提供了一种对医疗装置进行灭菌的方法，优选包括所述医疗装置的密封容器的内容物，其包括将所述医疗装置暴露于单色紫外线辐射的步骤，由此使嗜热脂肪芽孢杆菌（ATCC 7953）的D值至少为 在257nm处的23.7mJ / cm 2单色紫外线辐射对孢子。 此外，本发明提供对医疗装置进行灭菌的方法，包括以下步骤：对所述医疗装置进行单色紫外线辐射，其中到达所述医疗装置上存在的微生物的257nm处的所述单色紫外线辐射的最小总能量密度至少为 284mJ / cm 2。 本发明还提供一种用于将UV辐射递送到用于灭菌的医疗装置的装置，包括用于激光的激光器和扫描仪，使得在257nm处的至少284mJ / cm 2施加到所述医疗装置的治疗区域。 本发明提供一种方法和装置，其中可以在少于20秒，优选小于15秒，更优选在少于5秒内实现灭菌。 该方法和设备是有效和连续的。
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公开(公告)号：US08021608B2
公开(公告)日：2011-09-20
申请号：US12971486
申请日：2010-12-17
IPC分类号： A61L2/00 , B01J19/00 , B01J19/08 , A62B7/08 , G01N23/00 , B65D85/04 , B65D83/10 , B65D41/00 , B65B55/02
CPC分类号： A61L12/063 , A61L2/10 , B65B25/008
摘要： This invention provides a process of sterilizing a medical device, and preferably the contents of a sealed container which comprises said medical device, comprising the step of exposing said medical device to monochromatic ultraviolet radiation whereby the Dvalue of Bacillus stearothermophilus (ATCC 7953) is at least 23.7 mJ/cm2 monochromatic ultraviolet radiation at 257 nm to the spore. Further, this invention provides a process of sterilizing a medical device comprising the step of subjecting said medical device to monochromatic ultraviolet radiation wherein the minimum total energy density of said monochromatic ultraviolet radiation at 257 nm which reaches the microorganisms present on said medical device is at least 284 mJ/cm2.This invention further provides an apparatus for delivering UV radiation to a medical device for sterilization comprising a laser and a scanner for the laser such that at least 284 mJ/cm2 at 257 nm is applied to a treatment area for said medical device. This invention provides a process and apparatus in which sterilization can be achieved in less than 20 seconds, preferably less than 15 seconds, more preferably in less than 5 seconds. The process and apparatus are efficient and continuous.
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7.发明授权公开(公告)号：US08318089B2
公开(公告)日：2012-11-27
申请号：US13208452
申请日：2011-08-12
IPC分类号： A61L2/00 , B01J19/00 , B01J19/08 , A62B7/08 , G01N23/00 , B65D85/04 , B65D83/10 , B65D41/00 , A24F15/00 , B65B55/02
CPC分类号： A61L12/063 , A61L2/10 , B65B25/008
摘要： A processes of sterilizing a contact lens, that is immersed in an aqueous liquid and hermetically in a container, using at least 284 mJ/cm2 of UV radiation in the range of 240-280 nm is disclosed herein.
摘要翻译： 本文公开了使用在240-280nm范围内的至少284mJ / cm 2的紫外线辐射将隐形眼镜浸入含水液体并气密地在容器中进行灭菌的方法。
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8.发明授权Molded polymeric object with wettable surface made from latent-hydrophilic monomers 失效具有由潜亲水性单体制成的可润湿表面的成型聚合物
公开(公告)号：US5779943A
公开(公告)日：1998-07-14
申请号：US620685
申请日：1996-03-19
IPC分类号： G02C7/04 , B29C37/00 , B29C41/02 , B29D11/00 , C08J5/00 , C08J7/04 , C08L101/00 , C09D133/24 , C09D183/07 , C09D201/00 , G02B1/04 , G02B1/10
CPC分类号： G02B1/043 , B29C37/0032 , B29C41/02 , B29D11/00076 , B29D11/00125 , C08J5/00 , B29K2105/0002 , B29K2823/12
摘要： This invention provides a molded polymeric object, partially or completely coated with a hydrophilic polymer which provides a wettable surface to the molded object such as a contact lens. It also provides a process for using latent-hydrophilic monomers to make molded objects with wettable surfaces.
摘要翻译： 本发明提供了一种模制聚合物体，其部分或完全涂覆有亲水性聚合物，该亲水性聚合物为诸如隐形眼镜的模制物体提供可润湿的表面。 它还提供了一种使用潜亲水性单体来制造具有可润湿表面的模塑物体的方法。
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公开(公告)号：US06663801B2
公开(公告)日：2003-12-16
申请号：US09827995
申请日：2001-04-06
IPC分类号： B29D1100
CPC分类号： B29C43/021 , B29C37/0003 , B29C43/50 , B29C2035/0822 , B29D11/00211 , B29D11/00221 , B29K2105/0002 , B29L2011/0016 , B29L2011/0041 , Y10S425/808
摘要： A method and a device for removing molded soft contact lenses, high-precision intraocular lenses and the like, from the individual molds in which they are produced. Provided is an infra-red radiation or heater device constituted of silicon carbide IR-emitters, and which employs an individual infra-red emitter for each individual mold, to impart a desired thermal gradient.
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