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公开(公告)号：US20220080170A1
公开(公告)日：2022-03-17
申请号：US17240884
申请日：2021-04-26
申请人： Allergan, Inc.
发明人： Justin J. Schwab , Michael Augarten , Zachary Dominguez , Ethan Franklin , Edwin J. Kayda , Jason Metzner
摘要： A layered microneedle device can have successively stacked layers that each include microneedles and perforations positioned between the microneedles. The layers can be stacked to permit microneedles of a lower layer to extend through the perforations of an upper layer. Thus, microneedles of successively stacked layers can extend away from individual layers in a common direction.
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公开(公告)号：US10357615B2
公开(公告)日：2019-07-23
申请号：US15011897
申请日：2016-02-01
申请人： Allergan, Inc.
摘要： Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one pawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.
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公开(公告)号：US20150328405A1
公开(公告)日：2015-11-19
申请号：US14702581
申请日：2015-05-01
申请人： Allergan, Inc.
CPC分类号： A61M5/20 , A61M5/2046 , A61M5/31515 , A61M5/31576 , A61M2005/2026 , A61M2005/3152 , A61M2005/31588 , A61M2205/502 , A61M2205/52
摘要： Described herein are assisted syringes. The syringes provide a higher force to the plunger tip than the extrusion force applied to the plunger. The assisted syringes can be used to inject or extrude viscous materials.
摘要翻译： 这里描述的是辅助注射器。 注射器比施加到柱塞的挤压力提供比柱塞尖端更大的力。 辅助注射器可用于注射或挤出粘性物质。
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公开(公告)号：US20140350518A1
公开(公告)日：2014-11-27
申请号：US14284285
申请日：2014-05-21
申请人： Allergan, Inc.
IPC分类号： A61M5/31
CPC分类号： A61M5/31556 , A61M5/3137 , A61M5/31555 , A61M5/31581 , A61M5/5013 , A61M2005/3139
摘要： Described herein are syringe extrusion accessories comprising: a handle operatively coupled to an attachment portion configured to attach to a syringe; and at least one prawl operatively coupled to the handle and configured to engage with a plunger of the syringe, wherein the syringe extrusion accessory is configured to transfer a substantially perpendicular force applied to the handle to an axial force to push the plunger and extrude a product from the syringe.
摘要翻译： 这里描述的是注射器挤出附件，包括：手柄，可操作地联接到构造成附接到注射器的附接部分; 以及至少一个可操作地联接到所述手柄并且构造成与所述注射器的柱塞接合的铲斗，其中所述注射器挤出附件构造成将施加到所述手柄的基本上垂直的力传递到轴向力以推动所述柱塞并挤压产品 从注射器。
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公开(公告)号：US20240139422A1
公开(公告)日：2024-05-02
申请号：US18317731
申请日：2023-05-15
申请人： Allergan, Inc.
CPC分类号： A61M5/3137 , A61M5/31555 , A61M5/31556 , A61M5/31581 , A61M5/5013 , A61M2005/3139
摘要： A method of treatment may include providing a syringe having medicinal fluid therein for administering to a patient and coupling an attachment portion of an extrusion accessory having a handle and a pawl to a flange portion of the syringe. The pawl may have first and second ends, and be hingedly and rotatably coupled relative to the handle at a first position at the first end and at a second position between the first and second ends. The method may further include applying a force to translate the handle in a direction substantially perpendicular relative to a longitudinal axis of the syringe to cause axial movement of the second end of the pawl. The second end of the pawl may be engaged with a plunger of the syringe and axial movement of the second end of the pawl may drive the plunger forward to extrude the medicinal fluid from the syringe.
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公开(公告)号：US20160279401A1
公开(公告)日：2016-09-29
申请号：US14671690
申请日：2015-03-27
申请人： Allergan, Inc.
发明人： Justin J. Schwab , Michael Augarten , Zachary Dominguez , Ethan Franklin , Edwin J. Kayda , Jason Metzner
CPC分类号： A61M37/0015 , A61L31/042 , A61L31/148 , A61L31/16 , A61L2300/414 , A61L2300/428 , A61M2037/0023 , A61M2037/0046 , A61M2037/0061 , C08L5/08
摘要： A skin treatment device is provided including bioerodible polymeric microneedles which are designed to more effectively deliver beneficial agents to the skin. The device includes a flexible substrate and an arrangement, for example, an array, of microneedles projecting from the substrate.
摘要翻译： 提供了一种皮肤治疗装置，包括可生物降解的聚合物微针，其被设计成更有效地将有益的药剂递送至皮肤。 该装置包括柔性基板和从基板突出的微针阵列，例如阵列。
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公开(公告)号：US20240033492A1
公开(公告)日：2024-02-01
申请号：US18130490
申请日：2023-04-04
申请人： Allergan, Inc.
发明人： Justin J. Schwab , Michael Augarten , Zachary Dominguez , Ethan Franklin , Edwin J. Kayda , Jason Metzner
CPC分类号： A61M37/0015 , A61L31/042 , A61L31/148 , A61L31/16 , A61M2037/0023 , A61L2300/414 , A61L2300/428 , A61M2037/0046 , A61M2037/0061
摘要： A layered microneedle device can have successively stacked layers that each include microneedles and perforations positioned between the microneedles. The layers can be stacked to permit microneedles of a lower layer to extend through the perforations of an upper layer. Thus, microneedles of successively stacked layers can extend away from individual layers in a common direction.
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公开(公告)号：US10987503B2
公开(公告)日：2021-04-27
申请号：US16834731
申请日：2020-03-30
申请人： Allergan, Inc.
发明人： Justin J. Schwab , Michael Augarten , Zachary Dominguez , Ethan Franklin , Edwin J. Kayda , Jason Metzner
摘要： A skin treatment can include applying a microneedle device to a region of the skin so that microneedles of the device penetrate the stratum corneum. The arrangement of microneedles can have first microneedles with a first length and second microneedles with a second length, different from the first length. The first and second microneedles can be formed from a mixture of a polymeric material and an active agent beneficial to skin. After the device is applied to the skin, the first and second microneedles can be released below the skin surface, followed by dissolution of the first and second microneedles.
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公开(公告)号：US20210016008A1
公开(公告)日：2021-01-21
申请号：US17063721
申请日：2020-10-06
申请人： Allergan, Inc.
摘要： Described herein are assisted syringes. The syringes provide a higher force to the plunger tip than the extrusion force applied to the plunger. The assisted syringes can be used to inject or extrude viscous materials.
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公开(公告)号：US10265477B2
公开(公告)日：2019-04-23
申请号：US15064537
申请日：2016-03-08
申请人： Allergan, Inc.
摘要： Described herein are syringe accessories that can be attached to standard syringes. These accessories utilize one or more mechanisms that can provide at least one additional sensory feedback to the user when performing an aliquot or dosed injection. In other embodiments, the accessories can prevent overdosing.
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