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公开(公告)号：US20210307947A1
公开(公告)日：2021-10-07
申请号：US13972801
申请日：2013-08-21
申请人： Allergan, Inc.
发明人： Ethan Franklin , Justin Schwab
摘要： An implantable device used in a gastric band system includes an access port, a tube coupled to the access port, and a shielding device covering a portion of the tube. The shielding device is positioned adjacent to the access port and covers the end of the tube coupled to the access port. The shielding device is made from a puncture resistant material, to protect the tube from puncture by a misplaced syringe needle inserted by a physician.
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公开(公告)号：US10792427B2
公开(公告)日：2020-10-06
申请号：US16020951
申请日：2018-06-27
申请人： Allergan, Inc.
摘要： Described herein are assisted syringes. The syringes provide a higher force to the plunger tip than the extrusion force applied to the plunger. The assisted syringes can be used to inject or extrude viscous materials.
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公开(公告)号：US10603477B2
公开(公告)日：2020-03-31
申请号：US15903262
申请日：2018-02-23
申请人： Allergan, Inc.
发明人： Justin J. Schwab , Michael Augarten , Zachary Dominguez , Ethan Franklin , Edwin J. Kayda , Jason Metzner
摘要： A skin treatment device is provided including bioerodible polymeric microneedles which are designed to more effectively deliver beneficial agents to the skin. The device includes a flexible substrate and an arrangement, for example, an array, of microneedles projecting from the substrate.
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公开(公告)号：US20180229017A1
公开(公告)日：2018-08-16
申请号：US15903262
申请日：2018-02-23
申请人： Allergan, Inc.
发明人： Justin J. Schwab , Michael Augarten , Zachary Dominguez , Ethan Franklin , Edwin J. Kayda , Jason Metzner
CPC分类号： A61M37/0015 , A61L31/042 , A61L31/148 , A61L31/16 , A61L2300/414 , A61L2300/428 , A61M2037/0023 , A61M2037/0046 , A61M2037/0061 , C08L5/08
摘要： A skin treatment device is provided including bioerodible polymeric microneedles which are designed to more effectively deliver beneficial agents to the skin. The device includes a flexible substrate and an arrangement, for example, an array, of microneedles projecting from the substrate.
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公开(公告)号：US20140350517A1
公开(公告)日：2014-11-27
申请号：US14284268
申请日：2014-05-21
申请人： Allergan, Inc.
发明人： Zachary P. Dominguez , Tiago Bertolote , Ethan Franklin , Justin J. Schwab , Mike Augarten , Jason Metzner
CPC分类号： A61M5/31566 , A61M5/31501 , A61M5/486 , A61M5/5086 , A61M2005/3125 , A61M2005/3128 , A61M2005/31508 , A61M2005/3151 , A61M2205/3331 , A61M2205/583
摘要： Described are devices and systems for protection of injectable substances such as adipose cells from excessive stress or pressure during injection procedures. Further described are stress control mechanisms for detecting and/or controlling stress or pressure within injection devices.
摘要翻译： 描述了用于在注射过程中保护可注射物质例如脂肪细胞免受过度压力或压力的装置和系统。 进一步描述了用于检测和/或控制注射装置内的应力或压力的应力控制机构。
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公开(公告)号：US10987503B2
公开(公告)日：2021-04-27
申请号：US16834731
申请日：2020-03-30
申请人： Allergan, Inc.
发明人： Justin J. Schwab , Michael Augarten , Zachary Dominguez , Ethan Franklin , Edwin J. Kayda , Jason Metzner
摘要： A skin treatment can include applying a microneedle device to a region of the skin so that microneedles of the device penetrate the stratum corneum. The arrangement of microneedles can have first microneedles with a first length and second microneedles with a second length, different from the first length. The first and second microneedles can be formed from a mixture of a polymeric material and an active agent beneficial to skin. After the device is applied to the skin, the first and second microneedles can be released below the skin surface, followed by dissolution of the first and second microneedles.
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公开(公告)号：US20210016008A1
公开(公告)日：2021-01-21
申请号：US17063721
申请日：2020-10-06
申请人： Allergan, Inc.
摘要： Described herein are assisted syringes. The syringes provide a higher force to the plunger tip than the extrusion force applied to the plunger. The assisted syringes can be used to inject or extrude viscous materials.
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公开(公告)号：US20180304013A1
公开(公告)日：2018-10-25
申请号：US16020951
申请日：2018-06-27
申请人： Allergan, Inc.
CPC分类号： A61M5/20 , A61M5/2046 , A61M5/31515 , A61M5/31576 , A61M2005/2026 , A61M2005/3152 , A61M2005/31588 , A61M2205/502 , A61M2205/52
摘要： Described herein are assisted syringes. The syringes provide a higher force to the plunger tip than the extrusion force applied to the plunger. The assisted syringes can be used to inject or extrude viscous materials.
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公开(公告)号：US20160095984A1
公开(公告)日：2016-04-07
申请号：US14852903
申请日：2015-09-14
申请人： Allergan, Inc.
发明人： Ethan Franklin , Dimitrios Stroumpoulis , Zachary Dominguez , Justin Schwab , Bastien Mandaroux , Edwin Kayda
CPC分类号： A61M5/3298 , A61M5/19 , A61M5/204 , A61M5/31581 , A61M5/31593 , A61M5/321 , A61M5/326 , A61M5/3287 , A61M37/0015
摘要： Injection devices are provided which include a handpiece capable of housing a cartridge containing an injectable composition, and a head coupled to the handpiece and housing a plurality of retractable needles and a dosing mechanism. Methods of treating skin surfaces are also provided.
摘要翻译： 提供了注射装置，其包括能够容纳包含可注射组合物的药筒的手持件，以及联接到手持件并容纳多个可缩回针和定量给药机构的头部。 还提供了治疗皮肤表面的方法。
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公开(公告)号：US20130331643A1
公开(公告)日：2013-12-12
申请号：US13965041
申请日：2013-08-12
申请人： Allergan, Inc.
发明人： Sean Snow , Mitchell H. Babkes , Marcos Borrell , Christopher Deuel , Zachary Dominguez , Ethan Franklin , Babak Honaryar , Erik Torjesen
IPC分类号： A61F5/00
CPC分类号： A61F5/005 , A61F5/0063
摘要： Generally described herein are automatic, self-adjusting, gastric banding systems and improvements thereof, that are capable of automatically relaxing and contracting in response to a large bolus passing through the area of a patient's stomach constricted by a gastric band. Alternatively, and/or in addition in one or more embodiments, the gastric banding systems described herein may also help prevent pouch dilatation and/or erosion. The apparatus and systems described herein aid in facilitating obesity control and/or treating obesity-related diseases while generally being non-invasive once implanted. Furthermore, certain embodiments of the self-adjusting gastric banding systems disclosed herein are automatically adjustable without complicated fluid control mechanisms, flow rate limiting devices, and/or valves. The automatic adjustments may also be made in response to other changes in the patient's esophageal-gastric junction, for example, in response to size, shape, and or location changes.
摘要翻译： 本文通常描述的是自动，自调节，胃束带系统及其改进，其能够响应于穿过由胃束带收缩的患者胃的区域的大量推注而自动放松和收缩。 或者，和/或另外在一个或多个实施方案中，本文所述的胃束带系统还可以帮助防止囊膨胀和/或侵蚀。 本文所述的装置和系统有助于促进肥胖控制和/或治疗肥胖相关疾病，同时一般植入时是非侵入性的。 此外，本文公开的自调节胃束带系统的某些实施例可以在没有复杂的流体控制机构，流量限制装置和/或阀的情况下自动调节。 也可以响应于患者的食道 - 胃交界处的其它变化，例如响应于大小，形状和位置变化而进行自动调整。
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