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公开(公告)号：US20050137701A1
公开(公告)日：2005-06-23
申请号：US10746872
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0069
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。
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公开(公告)号：US20050137686A1
公开(公告)日：2005-06-23
申请号：US10746120
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/2439 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulic or non-pneumatic actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚固件上施加外部非液压或非气动致动力以改变所述锚的形状，诸如通过使用可释放的展开工具向锚固件施加近端和/或远端定向的力以使所述锚或 锚的部分。
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公开(公告)号：US20070010876A1
公开(公告)日：2007-01-11
申请号：US11531980
申请日：2006-09-14
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2439 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulic or non-pneumatic actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚固件上施加外部非液压或非气动致动力以改变所述锚的形状，诸如通过使用可释放的展开工具向锚固件施加近端和/或远端定向的力以使所述锚或 锚的部分。
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公开(公告)号：US20050137688A1
公开(公告)日：2005-06-23
申请号：US10746280
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/2412 , A61F2/2415 , A61F2/2418 , A61F2/2436 , A61F2210/0014 , A61F2220/0016 , A61F2220/0083 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/0039
摘要： A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site.
摘要翻译： 一种用于经皮置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以未膨胀构型经皮递送置换瓣膜和可扩张锚定至心脏瓣膜附近的步骤; 将锚扩展到展开构型，其中锚固件在第一锚固部位接触组织; 将锚重新定位到第二锚点; 并在第二锚点部署锚。
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公开(公告)号：US20050137695A1
公开(公告)日：2005-06-23
申请号：US10911059
申请日：2004-08-03
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider
IPC分类号： A61F2/24
CPC分类号： A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/0069
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：适于被血管内递送至心脏瓣膜附近的置换瓣膜; 可膨胀的锚固件适于被血管内递送到心脏瓣膜附近; 以及锁定机构，其构造成保持最小量的锚固膨胀。 本发明还包括一种用于血管内替换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将置换瓣膜和可扩张锚固件血管内输送到心脏瓣膜附近; 将锚扩展到部署配置; 并将锚定器锁定在部署的配置中。
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公开(公告)号：US20050137690A1
公开(公告)日：2005-06-23
申请号：US10746887
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/2418 , A61F2/2427 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: inserting a catheter having a diameter no more than 21 french into the patient; endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve through the catheter; and deploying the anchor and the replacement valve.
摘要翻译： 用于血管内替换患者心脏瓣膜的装置，包括：直径为21法郎或更小的输送导管; 布置在输送导管内的可扩张锚; 以及设置在输送导管内的置换瓣膜。 本发明还包括用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将具有不超过21个法兰的直径的导管插入患者体内; 通过导管将血管内递送更换瓣膜和可扩张锚固件到心脏瓣膜附近; 并部署锚杆和更换阀。
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公开(公告)号：US20050137689A1
公开(公告)日：2005-06-23
申请号：US10746285
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078 , A61F2250/006
摘要： A method for endovascularly replacing a heart valve of a patient. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor in an unexpanded configuration within a catheter to a vicinity of the heart valve; deploying the anchor from the catheter; expanding the anchor to contact tissue at an anchor site; and retrieving the anchor into the catheter. The invention also includes an apparatus for endovascularly replacing a heart valve, including: a catheter; a replacement valve configured to be disposed within the catheter for delivery to a vicinity of the heart valve; and an expandable anchor configured to be disposed within the catheter for delivery to a vicinity of the heart valve, to be deployed from the catheter, to be expanded to contact tissue at an anchor site and to be retrieved back into the catheter after having been expanded.
摘要翻译： 一种用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以下步骤：将导管内的未膨胀构造的置换瓣膜和可扩张锚固件输送到心脏瓣膜附近; 从导管部署锚杆; 扩大锚点以在锚点处接触组织; 并将锚固件取回到导管中。 本发明还包括用于血管内置换心脏瓣膜的装置，包括：导管; 配置成设置在所述导管内用于输送到所述心脏瓣膜附近的置换瓣膜; 以及被构造成设置在所述导管内用于输送到所述心脏瓣膜附近以从所述导管展开的可扩张锚，以被扩张以在锚固部位接触组织并且在扩张后被回收回到所述导管中 。
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公开(公告)号：US20050137687A1
公开(公告)日：2005-06-23
申请号：US10746240
申请日：2003-12-23
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9528 , A61F2220/0016 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2250/006
摘要： Apparatus for endovascularly replacing a patient's heart valve. In some embodiments the apparatus includes an expandable anchor with a lip region and a skirt region; and a replacement valve, wherein the lip region and skirt region are configured for percutaneous expansion to engage leaflets of the heart valve. The invention is also a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of endovascularly delivering apparatus including an anchor having lip and skirt regions, and a replacement valve coupled to the anchor, to a vicinity of the heart valve in a collapsed delivery configuration; and expanding the apparatus such that leaflets of the heart valve are captured between the lip and skirt regions of the anchor.
摘要翻译： 用于血管内置换患者心脏瓣膜的装置。 在一些实施例中，该装置包括具有唇部区域和裙部区域的可扩张锚固件; 以及替换阀，其中所述唇部区域和裙部区域构造成用于经皮膨胀以接合所述心脏瓣膜的小叶。 本发明也是用于血管内置换患者心脏瓣膜的方法。 在一些实施例中，该方法包括以折叠的输送配置将血管内递送设备包括具有唇缘和裙部区域的锚定器和连接到锚固器的置换瓣膜到心脏瓣膜附近的步骤; 并且扩张设备，使得心脏瓣膜的小叶被捕获在锚的唇缘和裙部区域之间。
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公开(公告)号：US20070244552A1
公开(公告)日：2007-10-18
申请号：US11732906
申请日：2007-04-04
申请人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
发明人： Amr Salahieh , Brian Brandt , Dwight Morejohn , Ulrich Haug , Jean-Pierre Dueri , Hans Valencia , Robert Geshlider , Jeff Krolik
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0065 , A61F2230/0078
摘要： Methods and devices for assessing the operation of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of a heart valve in an unexpanded configuration, and assessing the operation of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve. Methods and devices for assessing the location of a replacement heart valve. The method includes endovascularly delivering a replacement heart valve to a vicinity of the heart valve in an unexpanded configuration, expanding the replacement heart valve to a partially deployed configuration, and assessing the location of the replacement heart valve in the vicinity of the heart valve before fully expanding the replacement heart valve.
摘要翻译： 评估替换心脏瓣膜手术的方法和装置。 所述方法包括将心脏瓣膜置换成心脏瓣膜未发展的构造的血管内递送心脏瓣膜，并且在完全扩张置换心脏瓣膜之前评估心脏瓣膜附近的置换心脏瓣膜的操作。 评估置换心脏瓣膜位置的方法和装置。 该方法包括将心脏瓣膜置换为心脏瓣膜附近的未发展的构造，将替换心脏瓣膜扩张到部分展开的构造，并在充分地评估心脏瓣膜附近的位置 扩大更换心脏瓣膜。
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公开(公告)号：US20050143809A1
公开(公告)日：2005-06-30
申请号：US10982388
申请日：2004-11-05
申请人： Amr Salahieh , Jean-Pierre Dueri , Hans Valencia , Daniel Hildebrant , Brian Brandt , Dwight Morejohn , Claudio Argento , Tom Saul , Ulrich Haug
发明人： Amr Salahieh , Jean-Pierre Dueri , Hans Valencia , Daniel Hildebrant , Brian Brandt , Dwight Morejohn , Claudio Argento , Tom Saul , Ulrich Haug
CPC分类号： A61F2/2439 , A61F2/24 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/243 , A61F2/2433 , A61F2/2436 , A61F2/90 , A61F2002/9528 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/005 , A61F2230/0054 , A61F2230/0078 , A61F2230/008 , A61F2250/006
摘要： The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.
摘要翻译： 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法，包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状，例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力， 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具，其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件，以重构锚固件。
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