公开(公告)号：US20240384315A1

公开(公告)日：2024-11-21

申请号：US18688617

申请日：2022-09-02

Applicant: Amyris, Inc.

Inventor： Dominic PINEL ,  Victoria HSIAO ,  Diana Bahraini MARINA ,  Derek A. ABBOTT

IPC: C12P19/00 ,  A23L33/00 ,  C12N9/04 ,  C12N9/10 ,  C12N9/12 ,  C12N9/22 ,  C12N9/88 ,  C12N15/11 ,  C12N15/113 ,  C12N15/81

Abstract: Provided herein are host cells capable of producing a human milk oligosaccharide (HMO), such as yeast cells that are deficient in expression or activity of an endogenous oxidoreductase. Also provided are fermentation compositions including the disclosed host cells, as well as related methods of producing and recovering HMOs generated by the host cells.