公开(公告)号：US20150119364A1

公开(公告)日：2015-04-30

申请号：US14537771

申请日：2014-11-10

申请人： Anacor Pharmaceuticals, Inc.

发明人： Stephen J. BAKER ,  Tsutomu Akama ,  Michael Richard Kevin Alley ,  Stephen J. Benkovic ,  Michael DiPierro ,  Vincent S. Hernandez ,  Karin M. Hold ,  Isaac Kennedy ,  Igor Likhotvorik ,  Weimin Mao ,  Kirk Maples ,  Jacob J. Plattner ,  Fernando Rock ,  Virginia Sanders ,  Aaron M. Stemphoski ,  George Petros Yiannikouros ,  Siead Zegar ,  Yong-Kang Zhang ,  Huchen Zhou

IPC分类号： C07F5/04

CPC分类号： C07F5/025 ,  A61K9/0012 ,  A61K9/08 ,  A61K31/69 ,  A61K31/70 ,  A61K31/7076 ,  A61K47/10 ,  C07F5/04 ,  C07H19/06 ,  C07H19/16 ,  C07H21/00 ,  C07H23/00 ,  Y02A50/473

摘要： This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.

公开(公告)号：US09353133B2

公开(公告)日：2016-05-31

申请号：US14201459

申请日：2014-03-07

申请人： Anacor Pharmaceuticals, Inc.

发明人： Stephen J. Baker ,  Tsutomu Akama ,  Michael Richard Kevin Alley ,  Stephen J. Benkovic ,  Michael DiPierro ,  Vincent S. Hernandez ,  Karin M. Hold ,  Isaac Kennedy ,  Igor Likhotvorik ,  Weimin Mao ,  Kirk Maples ,  Jacob J. Plattner ,  Fernando Rock ,  Virginia Sanders ,  Aaron M. Stemphoski ,  George Petros Yiannikouros ,  Siead Zegar ,  Yong-Kang Zhang ,  Huchen Zhou

IPC分类号： C07F5/04 ,  C07F5/02 ,  C07H19/06 ,  C07H19/16 ,  C07H21/00 ,  C07H23/00 ,  A61K31/69 ,  A61K31/70 ,  A61K31/7076

CPC分类号： C07F5/025 ,  A61K9/0012 ,  A61K9/08 ,  A61K31/69 ,  A61K31/70 ,  A61K31/7076 ,  A61K47/10 ,  C07F5/04 ,  C07H19/06 ,  C07H19/16 ,  C07H21/00 ,  C07H23/00 ,  Y02A50/473

摘要： This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.