QUATERNISED AMMONIUM CYCLODEXTRIN COMPOUNDS
    3.
    发明申请
    QUATERNISED AMMONIUM CYCLODEXTRIN COMPOUNDS 审中-公开
    季铵化合物CYCLODEXTRIN化合物

    公开(公告)号:US20090110734A1

    公开(公告)日:2009-04-30

    申请号:US12238473

    申请日:2008-09-26

    摘要: Use of a compound of formula (I): wherein the symbol represents a n-valent residue derived from a cyclodextrin compound by removing n of its hydroxyl groups; n is a number greater than 0 and represents the average number of substituents of formula per molecule of said compound; h is 0 or 1; R1 is a di-valent group selected from alkylene, hydroxy alkylene, halogeno alkylene, monocyclic aralkylene, cycloalkylene and phenylene; R2, R3 and R4 are each independently of one another a group selected from alkyl, cycloalkyl, aryl, aralkyl, and cycloheteryl; xm− is a m-fold negatively charged anion; m is an integer being equal or greater than 1; and k is n/m in the preparation of an anti-infective medicament, as preservative and penetration enhancer.

    摘要翻译: 式(I)化合物的用途:其中符号表示通过除去其羟基而衍生自环糊精化合物的n价残基; n是大于0的数,表示每分子所述化合物的式的取代基的平均数; h为0或1; R1是选自亚烷基,羟基亚烷基,卤代亚烷基,单环亚芳基,亚环烷基和亚苯基的二价基团; R2,R3和R4各自独立地为选自烷基,环烷基,芳基,芳烷基和环戊基的基团; xm-是m-带负电荷的阴离子; m是等于或大于1的整数; 在制备抗感染药物中,k为n / m,作为防腐剂和渗透促进剂。

    Quaternised Ammonium Cyclodextrin Compounds
    6.
    发明申请
    Quaternised Ammonium Cyclodextrin Compounds 审中-公开
    季铵化环糊精化合物

    公开(公告)号:US20120004158A1

    公开(公告)日:2012-01-05

    申请号:US13234912

    申请日:2011-09-16

    摘要: Use of a compound of formula (I): wherein the symbol cyclodextrin ]n represents a n-valent residue derived from a cyclodextrin compound by removing n of its hydroxyl groups; n is a number greater than 0 and represents the average number of substituents of formula per molecule of said compound; h is 0 or 1; R1 is a di-valent group selected from alkylene, hydroxy alkylene, halogeno alkylene, monocyclic aralkylene, cycloalkylene and phenylene; R2, R3 and R4 are each independently of one another a group selected from alkyl, cycloalkyl, aryl, aralkyl, and cycloheteryl; Xm− is a m-fold negatively charged anion; m is an integer being equal or greater than 1; and k is n/m in the preparation of an anti-infective medicament, as preservative and penetration enhancer.

    摘要翻译: 式(I)化合物的用途:其中符号环糊精] n表示通过除去其羟基而衍生自环糊精化合物的n价残基; n是大于0的数,表示每分子所述化合物的式的取代基的平均数; h为0或1; R1是选自亚烷基,羟基亚烷基,卤代亚烷基,单环亚芳基,亚环烷基和亚苯基的二价基团; R2,R3和R4各自独立地为选自烷基,环烷基,芳基,芳烷基和环戊基的基团; Xm-是一个m-带负电荷的阴离子; m是等于或大于1的整数; 在制备抗感染药物中,k为n / m,作为防腐剂和渗透促进剂。