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    QUATERNISED AMMONIUM CYCLODEXTRIN COMPOUNDS
    2.
    发明申请
    QUATERNISED AMMONIUM CYCLODEXTRIN COMPOUNDS 审中-公开
    季铵化合物CYCLODEXTRIN化合物

    公开(公告)号：US20090110734A1

    公开(公告)日：2009-04-30

    申请号：US12238473

    申请日：2008-09-26

    申请人： Georg Ludwig Kis ,  Christian Schoch ,  Jozsef Szejtli

    发明人： Georg Ludwig Kis ,  Christian Schoch ,  Jozsef Szejtli

    IPC分类号： A61K9/10 ,  C07H15/04 ,  A61K31/7028 ,  A61K38/02

    CPC分类号： A61K31/724 ,  A61K31/196 ,  A61K31/4535 ,  C08B37/0012

    摘要： Use of a compound of formula (I): wherein the symbol represents a n-valent residue derived from a cyclodextrin compound by removing n of its hydroxyl groups; n is a number greater than 0 and represents the average number of substituents of formula per molecule of said compound; h is 0 or 1; R1 is a di-valent group selected from alkylene, hydroxy alkylene, halogeno alkylene, monocyclic aralkylene, cycloalkylene and phenylene; R2, R3 and R4 are each independently of one another a group selected from alkyl, cycloalkyl, aryl, aralkyl, and cycloheteryl; xm− is a m-fold negatively charged anion; m is an integer being equal or greater than 1; and k is n/m in the preparation of an anti-infective medicament, as preservative and penetration enhancer.

    摘要翻译： 式（I）化合物的用途：其中符号表示通过除去其羟基而衍生自环糊精化合物的n价残基; n是大于0的数，表示每分子所述化合物的式的取代基的平均数; h为0或1; R1是选自亚烷基，羟基亚烷基，卤代亚烷基，单环亚芳基，亚环烷基和亚苯基的二价基团; R2，R3和R4各自独立地为选自烷基，环烷基，芳基，芳烷基和环戊基的基团; xm-是m-带负电荷的阴离子; m是等于或大于1的整数; 在制备抗感染药物中，k为n / m，作为防腐剂和渗透促进剂。

    Quaternised Ammonium Cyclodextrin Compounds
    5.
    发明申请
    Quaternised Ammonium Cyclodextrin Compounds 审中-公开
    季铵化环糊精化合物

    公开(公告)号：US20120004158A1

    公开(公告)日：2012-01-05

    申请号：US13234912

    申请日：2011-09-16

    申请人： Georg Ludwig Kis ,  Christian Schoch ,  Jozsef Szejtli

    发明人： Georg Ludwig Kis ,  Christian Schoch ,  Jozsef Szejtli

    IPC分类号： A61K38/00 ,  A61P31/04 ,  A61K31/711 ,  A61P31/10 ,  A61K31/7105 ,  A61K31/715 ,  A61P31/00

    CPC分类号： A61K31/724 ,  A61K31/196 ,  A61K31/4535 ,  C08B37/0012

    摘要： Use of a compound of formula (I): wherein the symbol cyclodextrin ]n represents a n-valent residue derived from a cyclodextrin compound by removing n of its hydroxyl groups; n is a number greater than 0 and represents the average number of substituents of formula per molecule of said compound; h is 0 or 1; R1 is a di-valent group selected from alkylene, hydroxy alkylene, halogeno alkylene, monocyclic aralkylene, cycloalkylene and phenylene; R2, R3 and R4 are each independently of one another a group selected from alkyl, cycloalkyl, aryl, aralkyl, and cycloheteryl; Xm− is a m-fold negatively charged anion; m is an integer being equal or greater than 1; and k is n/m in the preparation of an anti-infective medicament, as preservative and penetration enhancer.

    摘要翻译： 式（I）化合物的用途：其中符号环糊精] n表示通过除去其羟基而衍生自环糊精化合物的n价残基; n是大于0的数，表示每分子所述化合物的式的取代基的平均数; h为0或1; R1是选自亚烷基，羟基亚烷基，卤代亚烷基，单环亚芳基，亚环烷基和亚苯基的二价基团; R2，R3和R4各自独立地为选自烷基，环烷基，芳基，芳烷基和环戊基的基团; Xm-是一个m-带负电荷的阴离子; m是等于或大于1的整数; 在制备抗感染药物中，k为n / m，作为防腐剂和渗透促进剂。