公开(公告)号：US20130197280A1

公开(公告)日：2013-08-01

申请号：US13519921

申请日：2010-12-29

申请人： Andrei Aleksandrovich Stepanov ,  Victor Filippovich Cherstkov ,  Mario Joseph Nappa

发明人： Andrei Aleksandrovich Stepanov ,  Victor Filippovich Cherstkov ,  Mario Joseph Nappa

IPC分类号： C07C17/35

CPC分类号： C07C17/35 ,  C07C17/23 ,  C07C21/18

摘要： Disclosed is a process for producing a hydrofluoroalkene, RfCF═CH2 comprising contacting a hydrofluoroalkanol of structure RfCF2CH2OH, with a lewis acid to produce a mixture, diluting said mixture with a solvent to produce a solvent mixture, contacting the solvent mixture with a reactive metal, heating the solvent mixture and reactive metal for a sufficient amount of time to produce a hydrofluoroalkene, and condensing and collecting the volatile products comprising the hydrofluoroalkene, wherein Rf is F, or a fluorine-substituted alkyl group.

摘要翻译： 公开了一种制备氢氟烯烃的方法，RfCF = CH2包括使结构RfCF 2 CH 2 OH的氢氟烷醇与路易斯酸接触以产生混合物，用溶剂稀释所述混合物以产生溶剂混合物，使溶剂混合物与活性金属接触， 加热溶剂混合物和反应性金属足够的时间以产生氢氟烯烃，并冷凝和收集包含其中Rf为F的氢氟烯烃或氟取代的烷基的挥发性产物。

公开(公告)号：US07728183B2

公开(公告)日：2010-06-01

申请号：US12278789

申请日：2007-04-03

申请人： Mario Joseph Nappa ,  Allen Capron Sievert ,  Victor Filippovich Cherstkov ,  Nina Ivanova Delyagina

发明人： Mario Joseph Nappa ,  Allen Capron Sievert ,  Victor Filippovich Cherstkov ,  Nina Ivanova Delyagina

IPC分类号： C07C17/38

CPC分类号： C07C17/395 ,  C07C303/24 ,  C07C305/06

摘要： A process is disclosed for reducing the mole ratio of (1) compounds of the formula Y1Y2C═CF2 wherein Y1 and Y2 are each independently H, F, Cl, Br, C1-C6 alkyl or C1-C6 haloalkyl containing no more than 3 chlorine substituents, 2 bromine substituents and 1 iodo substituent to (2) saturated compounds of the formula CdHeFfClgBrhIk wherein d is an integer from 1 to 10, and e+f+g+h+k is equal to 2d+2, provided that g is 0, 1, 2 or 3, h is 0, 1 or 2 and k is 0 or 1 and/or unsaturated compounds of the formula Y3Y4C═CY5Y6, wherein Y3, Y5 and Y6 are each independently H, F, Cl, Br, C1-C6 alkyl or C1-C6 haloalkyl containing no more than 3 chlorine substituents, 2 bromine substituents and 1 iodo substituent, provided that Y5 and Y6 are not both F, and Y4 is C1-C6 alkyl or C1-C6 haloalkyl containing no more than 3 chlorine substituents, 2 bromine substituents and 1 iodo substituent, in a mixture. The process involves contacting the mixture with at least one selective removal agent selected from the group consisting of SO3 and RSO3H, wherein R is selected from the group consisting of F, Cl, OH, C1-C8 alkyl, C1-C8 fluoroalkyl, and C1-C8 fluoroalkoxyalkyl containing no more than two ether oxygens to selectively react the formula Y1Y2C═CF2 compounds.

摘要翻译： 公开了一种降低（1）式Y1Y2C≡CF2化合物的摩尔比的方法，其中Y1和Y2各自独立地为H，F，Cl，Br，C1-C6烷基或含有不超过3个氯的C 1 -C 6卤代烷基 取代基，2个溴取代基和1个碘取代基与（2）式CdHeFfClgBrhIk的饱和化合物反应，其中d为1至10的整数，e + f + g + h + k等于2d + 2，条件是g为 0,1,2或3，h为0,1或2，k为0或1，和/或式Y3Y4C≡CY5Y6的不饱和化合物，其中Y3，Y5和Y6各自独立地为H，F，Cl，Br， 含有不超过3个氯取代基的C1-C6烷基或C1-C6卤代烷基，2个溴取代基和1个碘取代基，条件是Y5和Y6不同时为F，Y4为C1-C6烷基或不含任何更多的C 1 -C 6卤代烷基 3个氯取代基，2个溴取代基和1个碘取代基。 该方法包括使混合物与至少一种选自SO 3和RSO 3 H的选择性去除剂接触，其中R选自F，Cl，OH，C 1 -C 8烷基，C 1 -C 8氟烷基和C 1 含有不多于两个醚氧的-C8氟烷氧基烷基，以选择性地使式Y1Y2C≡CF2化合物反应。

公开(公告)号：US20090012336A1

公开(公告)日：2009-01-08

申请号：US12278789

申请日：2007-04-03

申请人： Mario Joseph Nappa ,  Allen Capron Sievert ,  Victor Filippovich Cherstkov ,  Nina Ivanova Delyagina

发明人： Mario Joseph Nappa ,  Allen Capron Sievert ,  Victor Filippovich Cherstkov ,  Nina Ivanova Delyagina

IPC分类号： C07C17/395

CPC分类号： C07C17/395 ,  C07C303/24 ,  C07C305/06

摘要： A process is disclosed for reducing the mole ratio of (1) compounds of the formula Y1Y2C═CF2 wherein Y1 and Y2 are each independently H, F, Cl, Br, C1-C6 alkyl or C1-C6 haloalkyl containing no more than 3 chlorine substituents, 2 bromine substituents and 1 iodo substituent to (2) saturated compounds of the formula CdHeFfClgBrhIk wherein d is an integer from 1 to 10, and e+f+g+h+k is equal to 2d+2, provided that g is 0, 1, 2 or 3, h is 0, 1 or 2 and k is 0 or 1 and/or unsaturated compounds of the formula Y3Y4C═CY5Y6, wherein Y3, Y5 and Y6 are each independently H, F, Cl, Br, C1-C6 alkyl or C1-C6 haloalkyl containing no more than 3 chlorine substituents, 2 bromine substituents and 1 iodo substituent, provided that Y5 and Y6 are not both F, and Y4 is C1-C6 alkyl or C1-C6 haloalkyl containing no more than 3 chlorine substituents, 2 bromine substituents and 1 iodo substituent, in a mixture. The process involves contacting the mixture with at least one selective removal agent selected from the group consisting of SO3 and RSO3H, wherein R is selected from the group consisting of F, Cl, OH, C1-C8 alkyl, C1-C8 fluoroalkyl, and C1-C8 fluoroalkoxyalkyl containing no more than two ether oxygens to selectively react the formula Y1Y2C═CF2 compounds.

摘要翻译： 公开了一种降低式（Y1）Y1Y2C-CF2化合物的摩尔比的方法，其中Y 1和Y 2各自独立地为H，F，Cl，Br，C 1 -C 6烷基或不超过3个氯的C 1 -C 6卤代烷基 取代基，2个溴取代基和1个碘取代基与（2）式CdHeFfClgBrhIk的饱和化合物反应，其中d为1至10的整数，e + f + g + h + k等于2d + 2，条件是g为 0,1,2或3，h为0,1或2，k为0或1，和/或式Y3Y4C-CY5Y6的不饱和化合物，其中Y3，Y5和Y6各自独立地为H，F，Cl，Br， 含有不超过3个氯取代基的C1-C6烷基或C1-C6卤代烷基，2个溴取代基和1个碘取代基，条件是Y5和Y6不同时为F，Y4为C1-C6烷基或不含任何更多的C 1 -C 6卤代烷基 3个氯取代基，2个溴取代基和1个碘取代基。 该方法包括使混合物与至少一种选自SO 3和RSO 3 H的选择性去除剂接触，其中R选自F，Cl，OH，C 1 -C 8烷基，C 1 -C 8氟烷基和C 1 含有不超过两个醚氧的-C8氟烷氧基烷基，以选择性地使式Y1Y2C-CF2化合物反应。

公开(公告)号：US09890311B2

公开(公告)日：2018-02-13

申请号：US14878381

申请日：2015-10-08

申请人： Mario Joseph Nappa ,  Barbara Haviland Minor ,  Allen Capron Sievert

发明人： Mario Joseph Nappa ,  Barbara Haviland Minor ,  Allen Capron Sievert

IPC分类号： C09K5/04 ,  F25B1/00 ,  F25B39/02 ,  C07C21/18 ,  F25B45/00 ,  F25B30/02 ,  F25B31/00 ,  F25B39/00

CPC分类号： C09K5/045 ,  C07C21/18 ,  C09K5/04 ,  C09K2205/126 ,  C09K2205/22 ,  C09K2205/40 ,  F25B1/00 ,  F25B30/02 ,  F25B31/002 ,  F25B39/00 ,  F25B39/02 ,  F25B45/00 ,  F25B2400/12 ,  F25B2400/121

摘要： The present invention relates to fluoroolefin compositions. The fluoroolefin compositions of the present invention are useful as refrigerants or heat transfer fluids and in processes for producing cooling or heat. Additionally, the fluoroolefin compositions of the present invention may be used to replace currently used refrigerant or heat transfer fluid compositions that have higher global warming potential.

公开(公告)号：US08668791B2

公开(公告)日：2014-03-11

申请号：US13313458

申请日：2011-12-07

申请人： Thomas J. Leck ,  Barbara Haviland Minor ,  Mario Joseph Nappa ,  Nandini C. Mouli ,  Jon Lee Howell

发明人： Thomas J. Leck ,  Barbara Haviland Minor ,  Mario Joseph Nappa ,  Nandini C. Mouli ,  Jon Lee Howell

IPC分类号： C09K5/04

CPC分类号： C09K5/045 ,  C09K2205/126

摘要： The present disclosure relates to compositions comprising at least one fluoroolefin and an effective amount of a stabilizer comprising at least one ascorbic acid, terephthalate, or nitromethane, or mixtures thereof. The stabilized compositions may be useful in cooling apparatus, such as refrigeration, air-conditioning, chillers and heat pumps, as well as in applications as foam blowing agents, solvents, aerosol propellants, fire extinguishants, and sterilants.

摘要翻译： 本公开涉及包含至少一种氟代烯烃和有效量的包含至少一种抗坏血酸，对苯二甲酸酯或硝基甲烷或其混合物的稳定剂的组合物。 稳定的组合物可用于冷却装置，例如制冷，空调，冷却器和热泵，以及作为泡沫发泡剂，溶剂，气溶胶推进剂，灭火剂和灭菌剂的应用。

公开(公告)号：US08529786B2

公开(公告)日：2013-09-10

申请号：US12377474

申请日：2007-08-31

申请人： Thomas J. Leck ,  Nandini C. Mouli ,  Barbara Haviland Minor ,  Mario Joseph Nappa ,  Jon Lee Howell

发明人： Thomas J. Leck ,  Nandini C. Mouli ,  Barbara Haviland Minor ,  Mario Joseph Nappa ,  Jon Lee Howell

IPC分类号： C09K5/04

CPC分类号： C09K5/045 ,  C09K2205/126

摘要： The present disclosure relates to compositions comprising at least one fluoroolefin and an effective amount of a stabilizer comprising at least one phosphorus-containing compound selected from the group consisting of thiophosphates, butylated triphenylphosphorothionates, and organophosphates. The stabilized compositions may be useful in cooling apparatus, such as refrigeration, air-conditioning, chillers and heat pumps, as well as in applications as foam blowing agents, solvents, aerosol propellants, fire extinguishants, and sterilants.

摘要翻译： 本公开涉及包含至少一种氟代烯烃和有效量的稳定剂的组合物，其包含至少一种选自硫代磷酸酯，丁基化三苯基硫代硫酸酯和有机磷酸酯的含磷化合物。 稳定的组合物可用于冷却装置，例如制冷，空调，冷却器和热泵，以及作为泡沫发泡剂，溶剂，气溶胶推进剂，灭火剂和灭菌剂的应用。

公开(公告)号：US08518294B2

公开(公告)日：2013-08-27

申请号：US13405657

申请日：2012-02-27

申请人： Mario Joseph Nappa ,  Xuehui Sun

发明人： Mario Joseph Nappa ,  Xuehui Sun

IPC分类号： C09K5/04

CPC分类号： C09K5/045 ,  C09K2205/126

摘要： Compositions comprising CF3CClFCH2OH, CF3CClFCH2OZnCl, and CF3CClFCH2OC(═O)CH3 are useful in processes to make HFO-1234yf. Compositions comprising HFO-1234yf may comprise at least one additional compound selected from the group consisting of CFC-114a, HCFC-124, HFC-143a, CFO-1113, HFO-1123, HFO-1132a, tetrafluoroethene, HCFO-1122, 3,4,4,4-tetrafluoro-2-butanone, acetyl fluoride, 2-chloro-2,3,3,3-tetrafluoropropanol, 2-chloro-2,3,3,3-tetrafluoropropyl acetate, Zinc (2-chloro-2,3,3,3-tetrafluoropropoxy) chloride, 2-chloro-2,3,3,3-tetrafluoropropoxy methyl acetate, 1,3-bistrifluoromethyl-1,3-difluorocyclobutane, 2,3,3,3-tetrafluoropropyl acetate, dimethylformamide, pyridine, ethyl acetate, acetic acid, diethyl ether, acetic anhydride, methyl acetate, dimethylacetamide, methanol, ethanol, methyl formate, pyrazine, pyrimidine, N-methylpyrrolidine, N-methylpiperidine, hexamethylphosphoramide, tetrahydrofuran, 1,4-dioxane, N-methylpyrrolidinone, dimethyl sulfoxide, acetonitrile, benzonitrile, and mixtures thereof. Compositions comprising HFO-1234yf are useful, among other uses, as heat transfer compositions for use in refrigeration, air-conditioning and heat pump systems.

摘要翻译： 包含CF 3 CClFCH 2 OH，CF 3 CClFCH 2 OZnCl和CF 3 CClFCH 2 OC（= O）CH 3的组合物可用于制备HFO-1234yf的方法中。 包含HFO-1234yf的组合物可以包含至少一种选自CFC-114a，HCFC-124，HFC-143a，CFO-1113，HFO-1123，HFO-1132a，四氟乙烯，HCFO-1122,3， 4,4,4-四氟-2-丁酮，乙酰氟，2-氯-2,3,3,3-四氟丙醇，2-氯-2,3,3,3-四氟丙基乙酸酯，锌（2-氯 - 2,3,3,3-四氟丙氧基）氯化物，2-氯-2,3,3,3-四氟丙氧基甲酸乙酯，1,3-双三氟甲基-1,3-二氟环丁烷，乙酸2,3,3,3-四氟丙酯 吡啶，乙酸乙酯，乙酸甲酯，二甲基乙酰胺，甲醇，乙醇，甲酸甲酯，吡嗪，嘧啶，N-甲基吡咯烷，N-甲基哌啶，六甲基磷酰胺，四氢呋喃，1,4-二恶烷 ，N-甲基吡咯烷酮，二甲基亚砜，乙腈，苄腈及其混合物。 包括HFO-1234yf的组合物在其它用途中可用作用于制冷，空调和热泵系统的热传递组合物。

公开(公告)号：US08445735B2

公开(公告)日：2013-05-21

申请号：US13478253

申请日：2012-05-23

申请人： Mario Joseph Nappa

发明人： Mario Joseph Nappa

IPC分类号： C07C17/25

CPC分类号： C07C17/25 ,  C07C21/18

摘要： Described is a method for producing fluoropropenes of formula CF3CX═CX2 wherein each X is F or H, at least one X is H, and at least one X is F, comprising pyrolyzing a hydrofluorochloropropane of formula CF3CXYCX2Y, wherein each X is F or H, at least one X is H, and at least one X is F, and one Y is Cl and the other Y is H, in the gas-phase in a reaction vessel, maintained at a temperature high enough to effect the pyrolysis of said hydrofluorochloropropane to said fluoropropene, wherein the selectivity for the production of the fluoropropene is at least 80%, in he absence of a catalyst.

摘要翻译： 描述了制备式CF 3 C X = CX 2的氟丙烯的方法，其中每个X是F或H，至少一个X是H，并且至少一个X是F，包括热解式CF 3 C XYCX 2 Y的氢氟氯丙烷，其中每个X是F或H ，至少一个X是H，至少一个X是F，一个Y是Cl，另一个Y是H，在反应容器中的气相中，保持在足够高的温度下，使所说的 氢氟丙烷与所述氟丙烯反应，其中在不存在催化剂的情况下，氟代丙烯的制备选择性为至少80％。

公开(公告)号：US20120267567A1

公开(公告)日：2012-10-25

申请号：US13539963

申请日：2012-07-02

申请人： VELLIYUR NOTT MALLIKARJUNA RAO ,  Mario Joseph Nappa ,  Allen Capron Sievert

发明人： VELLIYUR NOTT MALLIKARJUNA RAO ,  Mario Joseph Nappa ,  Allen Capron Sievert

IPC分类号： C09K3/00

CPC分类号： C09K5/045 ,  C07C17/00 ,  C07C17/087 ,  C07C17/206 ,  C07C17/23 ,  C07C17/354 ,  C07C19/08 ,  C07C19/10 ,  C07C21/18

摘要： A process is disclosed for making CF3CF═CHF. The process involves reacting CF3CClFCCl2F with H2 in a reaction zone in the presence of a catalyst to produce a product mixture comprising CF3CF═CHF. The catalyst has a catalytically effective amount of palladium supported on a support selected from the group consisting of alumina, fluorided alumina, aluminum fluoride and mixtures thereof and the mole ratio of H2 to CF3CClFCCl2F fed to the reaction zone is between about 1:1 and about 5:1.Also disclosed are azeotropic compositions of CF3CClFCCl2F and HF and azeotropic composition of CF3CHFCH2F and HF.

摘要翻译： 公开了一种制备CF 3 CF = CHF的方法。 该方法包括在反应区中在催化剂存在下使CF 3 CClFCCl 2 F与H 2反应以产生包含CF 3 CF = CHF的产物混合物。 催化剂具有负载在选自氧化铝，氟化氧化铝，氟化铝及其混合物的载体上的催化有效量的钯，并且进料至反应区的H 2与CF 3 CClFCCl 2 F的摩尔比为约1:1至约 5：1。 还公开了CF 3 CClFCCl 2 F和HF的共沸组合物和CF 3 CHFCH 2 F和HF的共沸组合物。

公开(公告)号：US08287752B2

公开(公告)日：2012-10-16

申请号：US11590453

申请日：2006-10-31

申请人： Mario Joseph Nappa ,  Ekaterina N. Swearingen ,  Allen Capron Sievert

发明人： Mario Joseph Nappa ,  Ekaterina N. Swearingen ,  Allen Capron Sievert

IPC分类号： A62D1/00 ,  C09K21/00

CPC分类号： A62D1/0057 ,  A62D1/00 ,  A62D1/005 ,  C09K3/30 ,  C09K21/08 ,  Y10T137/0318

摘要： Disclosed herein are flame suppression compounds and methods of use thereof. The compounds include unsaturated fluorocarbons appropriate for use in fire protection applications.

摘要翻译： 本文公开了阻燃化合物及其使用方法。 这些化合物包括适用于消防应用的不饱和碳氟化合物。