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    ANNULOPLASTY APPARATUS AND METHODS
    1.
    发明申请
    ANNULOPLASTY APPARATUS AND METHODS 失效
    ANNULOPLASTY装置和方法

    公开(公告)号：US20110004298A1

    公开(公告)日：2011-01-06

    申请号：US12880823

    申请日：2010-09-13

    申请人： Andrew Lee ,  Norman Fung ,  John D. Nguyen ,  Nga T. Doan ,  Laurent Schaller

    发明人： Andrew Lee ,  Norman Fung ,  John D. Nguyen ,  Nga T. Doan ,  Laurent Schaller

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61F2/2442

    摘要： An annuloplasty system for repairing a valve in a patient's heart comprises a surgical implant including a member having first and second end portions. The implant member further is configured and/or adapted to form a partial ring along a portion of one of the valve annulae of a patient's heart such as the mitral or tricuspid valve annulus. The implant member is axially elastic such that it can axially expand and contract and includes first and second anchors extending from the end portions of the implant member. The anchors are adapted to anchor the implant in tissue such as the mitral or tricuspid valve annulus. The system can facilitate tissue plication (e.g., of the posterior annulus of the mitral valve or the annulus of the tricuspid valve) and reinforcement of a valve annulus.

    摘要翻译： 用于修复患者心脏中的瓣膜的瓣环成形术系统包括外科植入物，其包括具有第一和第二端部的构件。 植入物构件还被构造和/或适于沿着患者心脏的瓣膜瓣的一部分形成部分环，例如二尖瓣或三尖瓣瓣环。 植入物构件具有轴向弹性，使得其可以轴向膨胀和收缩，并且包括从植入构件的端部延伸的第一和第二锚定件。 锚固件适于将植入物锚定在诸如二尖瓣或三尖瓣瓣环的组织中。 该系统可以促进组织塌陷（例如，二尖瓣的后部环或三尖瓣的环）并加强瓣膜环。

    Annuloplasty apparatus and methods
    2.
    发明授权
    Annuloplasty apparatus and methods 失效
    瓣膜成形术装置及方法

    公开(公告)号：US08167933B2

    公开(公告)日：2012-05-01

    申请号：US12880823

    申请日：2010-09-13

    申请人： Andrew Lee ,  Norman Fung ,  John D. Nguyen ,  Nga T. Doan ,  Laurent Schaller

    发明人： Andrew Lee ,  Norman Fung ,  John D. Nguyen ,  Nga T. Doan ,  Laurent Schaller

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2451 ,  A61F2/2442

    摘要： An annuloplasty system for repairing a valve in a patient's heart comprises a surgical implant including a member having first and second end portions. The implant member further is configured and/or adapted to form a partial ring along a portion of one of the valve annulae of a patient's heart such as the mitral or tricuspid valve annulus. The implant member is axially elastic such that it can axially expand and contract and includes first and second anchors extending from the end portions of the implant member. The anchors are adapted to anchor the implant in tissue such as the mitral or tricuspid valve annulus. The system can facilitate tissue plication (e.g., of the posterior annulus of the mitral valve or the annulus of the tricuspid valve) and reinforcement of a valve annulus.

    摘要翻译： 用于修复患者心脏中的瓣膜的瓣环成形术系统包括外科植入物，其包括具有第一和第二端部的构件。 植入物构件还被构造和/或适于沿着患者心脏的瓣膜瓣的一部分形成部分环，例如二尖瓣或三尖瓣瓣环。 植入物构件具有轴向弹性，使得其可以轴向膨胀和收缩，并且包括从植入构件的端部延伸的第一和第二锚定件。 锚固件适于将植入物锚定在诸如二尖瓣或三尖瓣瓣环的组织中。 该系统可以促进组织塌陷（例如，二尖瓣的后部环或三尖瓣的环）并加强瓣膜环。

    Minimally invasive annuloplasty procedure and apparatus
    4.
    发明授权
    Minimally invasive annuloplasty procedure and apparatus 失效
    微创瓣膜成形术程序和装置

    公开(公告)号：US06918917B1

    公开(公告)日：2005-07-19

    申请号：US09686729

    申请日：2000-10-10

    申请人： John D. Nguyen ,  Arthur Hill ,  Laurent Schaller

    发明人： John D. Nguyen ,  Arthur Hill ,  Laurent Schaller

    IPC分类号： A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/08 ,  A61F2/24 ,  A61B17/10

    CPC分类号： A61B17/064 ,  A61B17/0469 ,  A61B17/06 ,  A61B2017/0472 ,  A61B2017/06009 ,  A61B2017/06057 ,  A61B2017/081 ,  A61F2/2445 ,  A61F2/2466

    摘要： Clips of a self-closing type are used in annuloplasty procedures. Each clip is generally U-shaped with two end points separated from each other when it is constrained to be in an open configuration, but tends to coil up to assume its naturally closed configuration if the constraint is removed. A plurality of such clips in open configurations penetrate the tissue around the annulus circumferentially and then the constraint keeping them in the open configuration is removed such that they pull the tissue together between their two end points and this tends to reduce the diameter of the annulus. Such clips may be deployed each in the form of a clip assembly, having at least one of its end points connected to a needle through a flexible member and a release mechanism by which the clip can be easily released. The needle is caused to penetrate the tissue at one position and to come out therefrom at another circumferentially separated positions. Alternatively, a clip delivery device may be used with a plurality of such clips loaded to a clip-holder serving to keep them in open configurations. A pusher pushes the loaded clips out of the device one at a time. Self-closing clips can be used efficiently also in ring annuloplasty and valve replacement procedures.

    摘要翻译： 自闭型的夹子用于瓣环成形术。 每个夹子通常是U形的，当限制为处于打开构型时，两个端点彼此分开，但是如果约束被去除，则趋于线圈化以呈现其自然关闭的构造。 多个这样的打开构型的夹子沿圆周方向穿过环带周围的组织，然后去除保持它们处于打开构型的约束，使得它们将组织拉在它们的两个端点之间，这倾向于减小环的直径。 这样的夹子可以以夹子组件的形式展开，夹具组件的至少一个端点通过柔性构件连接到针头，释放机构通过该释放机构可以容易地释放夹子。 引导针在一个位置穿透组织，并在另一个周向分开的位置从其中脱出。 或者，剪辑传送设备可以与多个这样的夹子一起使用，这些夹子被加载到夹持器，用于使它们保持打开的配置。 一个推动器一次将装载的夹子推出设备。 自闭合夹可以有效地用于环瓣成形术和瓣膜置换手术。

    Minimally invasive valve repair procedure and apparatus
    6.
    发明授权
    Minimally invasive valve repair procedure and apparatus 有权
    微创性瓣膜修复手术及装置

    公开(公告)号：US07914544B2

    公开(公告)日：2011-03-29

    申请号：US11007825

    申请日：2004-12-07

    申请人： John D. Nguyen ,  Laurent Schaller ,  Art Hill

    发明人： John D. Nguyen ,  Laurent Schaller ,  Art Hill

    IPC分类号： A61B17/08

    CPC分类号： A61B17/064 ,  A61B17/0469 ,  A61B17/06 ,  A61B2017/0472 ,  A61B2017/06009 ,  A61B2017/06057 ,  A61B2017/081 ,  A61F2/2442

    摘要： A clip of a self-closing type is used for valve repair. The clip is generally U-shaped with two end points separated from each other when constrained to be in an open configuration, but tends to coil up to assume its natural closed configuration if the constraint is removed. At least one end point is connected through a suture to a tissue-penetrating needle. A needle holder has an outer tube and an inner member which has a slit at the front and is slidable inside the outer tube. A double-arm clip assembly with each of the end points of the clip attached through a suture to a separate needle may be used for valve repair and may contain two of such clips mutually connected by a flexible connector whereby two leaflets are held together by the connector, with the two clips each anchored to a corresponding one of the leaflets.

    摘要翻译： 自动关闭型的夹子用于阀门修理。 夹子通常是U形的，当限制为处于打开构型时，两个端点彼此分开，但是如果约束被去除，则倾向于卷起以呈现其自然闭合构型。 至少一个端点通过缝合线连接到组织穿透针。 针保持器具有外管和内部构件，其在前部具有狭缝并且可在外管内滑动。 双臂夹组合件，其夹子的每个端点通过缝合线连接到单独的针上，可以用于阀修复，并且可以包含两个这样的夹子，这些夹子通过柔性连接器相互连接，由此两个传单由 连接器，其中两个夹子各自固定到相应的一个传单。

    Minimally invasive annuloplasty procedure and apparatus
    9.
    发明授权
    Minimally invasive annuloplasty procedure and apparatus 失效

    公开(公告)号：US06921407B2

    公开(公告)日：2005-07-26

    申请号：US10120579

    申请日：2002-04-10

    申请人： John D. Nguyen ,  Arthur Hill ,  Laurent Schaller

    发明人： John D. Nguyen ,  Arthur Hill ,  Laurent Schaller

    IPC分类号： A61B17/04 ,  A61B17/06 ,  A61B17/064 ,  A61B17/08 ,  A61F2/24 ,  A61B17/10

    CPC分类号： A61B17/064 ,  A61B17/0469 ,  A61B17/06 ,  A61B2017/0472 ,  A61B2017/06009 ,  A61B2017/06057 ,  A61B2017/081 ,  A61F2/2445 ,  A61F2/2466

    摘要： Clips of a self-closing type are used in annuloplasty procedures. Each clip is generally U-shaped with two end points separated from each other when it is constrained to be in an open configuration, but tends to coil up to assume its naturally closed configuration if the constraint is removed. A plurality of such clips in open configurations penetrate the tissue around the annulus circumferentially and then the constraint keeping them in the open configuration is removed such that they pull the tissue together between their two end points and this tends to reduce the diameter of the annulus. Such clips may be deployed each in the form of a clip assembly, having at least one of its end points connected to a needle through a flexible member and a release mechanism by which the clip can be easily released. The needle is caused to penetrate the tissue at one position and to come out therefrom at another circumferentially separated positions. Alternatively, a clip delivery device may be used with a plurality of such clips loaded to a clip-holder serving to keep them in open configurations. A pusher pushes the loaded clips out of the device one at a time. Self-closing clips can be used efficiently also in ring annuloplasty and valve replacement procedures.