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    SYSTEMS AND METHODS FOR ENSURING SAFE AND RAPID DEPLOYMENT OF PROSTHETIC HEART VALVES
    2.
    发明申请
    SYSTEMS AND METHODS FOR ENSURING SAFE AND RAPID DEPLOYMENT OF PROSTHETIC HEART VALVES 有权
    确保安全和快速部署预防心脏瓣膜的系统和方法

    公开(公告)号：US20130245751A1

    公开(公告)日：2013-09-19

    申请号：US13797572

    申请日：2013-03-12

    申请人： Andrew Phung ,  August R. Yambao ,  Faisal Kalam ,  William C. Brunnett ,  Rafael Pintor ,  Michael J. Scott

    发明人： Andrew Phung ,  August R. Yambao ,  Faisal Kalam ,  William C. Brunnett ,  Rafael Pintor ,  Michael J. Scott

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2433 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0008 ,  A61F2220/0016

    摘要： A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A system and method for deployment includes an integrated handle shaft and balloon catheter. A safety member disposed between the balloon catheter and handle shaft prevents premature catheter advancement prior to heart valve placement at the annulus, and also may prevent premature balloon inflation prior to full catheter advancement.

    摘要翻译： 提供了一种快速连接的心脏瓣膜假体，可以在手术过程中快速方便地植入。 心脏瓣膜可以包括基本上不可膨胀的，不可压缩的人造瓣膜和可塑性可扩张的框架，从而使得能够在没有缝线的情况下附接到环形区域。 一种用于部署的系统和方法包括一体式手柄轴和球囊导管。 设置在球囊导管和手柄轴之间的安全构件防止在心瓣膜置于环形空间之前过早的导管前进，并且还可以在全导管前进之前防止过早的球囊膨胀。

    Quick-connect prosthetic heart valve and methods
    3.
    发明授权
    Quick-connect prosthetic heart valve and methods 有权
    快速连接假体心脏瓣膜和方法

    公开(公告)号：US08308798B2

    公开(公告)日：2012-11-13

    申请号：US12635471

    申请日：2009-12-10

    申请人： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August Yambao ,  Louis Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey Cristea ,  Faisal Kalam

    发明人： Rafael Pintor ,  Mark Chau ,  Travis Oba ,  August Yambao ,  Louis Campbell ,  Tammy Huntley ,  Qinggang Zeng ,  Carey Cristea ,  Faisal Kalam

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2409 ,  A61F2/243 ,  A61F2/2433 ,  A61F2220/0016 ,  A61F2220/0025 ,  A61F2220/005 ,  A61F2220/0075 ,  A61F2220/0083 ,  A61F2230/0054 ,  A61F2230/0067 ,  A61F2230/0069 ,  A61F2230/0078 ,  A61F2250/006

    摘要： A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent. The base stent may take the form of a self- or balloon-expandable stent that expands outward against the native valve with or without leaflet excision. The valve component has a non-expandable prosthetic valve and a self- or balloon-expandable coupling stent for attachment to the base stent, thereby fixing the position of the valve component relative to the base stent. The prosthetic valve may be a commercially available to valve with a sewing ring and the coupling stent attaches to the sewing ring. The system is particularly suited for rapid deployment of heart valves in a conventional open-heart surgical environment. A catheter-based system and method for deployment is provided.

    摘要翻译： 提供了可以在手术过程中快速且容易地植入的心脏瓣膜假体。 假体瓣膜具有部署在治疗部位的基部支架和构造成快速连接到基部支架的阀部件。 基底支架可以采取自体或球囊扩张的支架的形式，其在具有或不具有小叶切除的情况下相对于天然瓣膜向外扩张。 阀部件具有不可扩张的假体瓣膜和用于附接到基底支架的自支撑或球囊扩张的联接支架，由此固定阀部件相对于基底支架的位置。 人造瓣膜可以是市售的，具有缝合环的阀门，并且联接支架附接到缝合环。 该系统特别适用于在常规开心手术环境中快速部署心脏瓣膜。 提供了基于导管的系统和部署方法。

    PROSTHETIC HEART VALVE PACKAGING AND DEPLOYMENT METHODS
    4.
    发明申请
    PROSTHETIC HEART VALVE PACKAGING AND DEPLOYMENT METHODS 有权
    前置心脏瓣膜包装和部署方法

    公开(公告)号：US20120150288A1

    公开(公告)日：2012-06-14

    申请号：US13403537

    申请日：2012-02-23

    申请人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    发明人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    IPC分类号： A61F2/24

    CPC分类号： A61F2/2427 ,  A61F2/0095 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075

    摘要： Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

    摘要翻译： 用于假体心脏瓣膜的包装，包括用于将心脏瓣膜牢固地保持在罐内并有助于从其中取出的组件。 组件包括紧密地配合在罐内的包装套筒，并具有用于固定阀座的夹子结构。 与以前的设计相反，在一个实施例中，阀保持器向下指向罐中，并且阀向上保持流入端。 阀可以具有柔性小叶，并且在轴的端部上的小叶分离构件延伸穿过叶片并与阀座联接。 然后可以将包装套筒，阀和保持器的组件从罐中移除，以及与保持器连接的阀输送管，或者与叶片分离构件相连。 包装套筒可以分叉成在活动铰链处连接的两个半部，以便于从阀/支架子组件周围移除。

    Prosthetic heart valve packaging and deployment methods
    5.
    发明授权
    Prosthetic heart valve packaging and deployment methods 有权
    假体心脏瓣膜包装和部署方法

    公开(公告)号：US09295539B2

    公开(公告)日：2016-03-29

    申请号：US13403537

    申请日：2012-02-23

    申请人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    发明人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    IPC分类号： A61F2/00 ,  A61F2/24

    CPC分类号： A61F2/2427 ,  A61F2/0095 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075

    摘要： Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly.

    摘要翻译： 用于假体心脏瓣膜的包装，包括用于将心脏瓣膜牢固地保持在罐内并有助于从其中取出的组件。 组件包括紧密地配合在罐内的包装套筒，并具有用于固定阀座的夹子结构。 与以前的设计相反，在一个实施例中，阀保持器向下指向罐中，并且阀向上保持流入端。 阀可以具有柔性小叶，并且在轴的端部上的小叶分离构件延伸穿过叶片并与阀座联接。 然后可以将包装套筒，阀和保持器的组件从罐中移除，以及与保持器连接的阀输送管，或者与叶片分离构件相连。 包装套筒可以分叉成在活动铰链处连接的两个半部，以便于从阀/支架子组件周围移除。

    Prosthetic heart valve packaging and deployment system
    7.
    发明授权
    Prosthetic heart valve packaging and deployment system 有权
    假心脏瓣膜包装和部署系统

    公开(公告)号：US08869982B2

    公开(公告)日：2014-10-28

    申请号：US12969238

    申请日：2010-12-15

    申请人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    发明人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    IPC分类号： A61B17/06 ,  A61B19/02 ,  A61L15/00 ,  A61F2/00 ,  A61F2/24

    CPC分类号： A61F2/2427 ,  A61F2/0095 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075

    摘要： Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly. The packaging system facilitates attachment of the valve delivery tube for use in a quick-connect valve implant procedure.

    摘要翻译： 用于假体心脏瓣膜的包装，包括用于将心脏瓣膜牢固地保持在罐内并有助于从其中取出的组件。 组件包括紧密地配合在罐内的包装套筒，并具有用于固定阀座的夹子结构。 与以前的设计相反，在一个实施例中，阀保持器向下指向罐中，并且阀向上保持流入端。 阀可以具有柔性小叶，并且在轴的端部上的小叶分离构件延伸穿过叶片并与阀座联接。 然后可以将包装套筒，阀和保持器的组件从罐中移除，以及与保持器连接的阀输送管，或者与叶片分离构件相连。 包装套筒可以分叉成在活动铰链处连接的两个半部，以便于从阀/支架子组件周围移除。 该包装系统便于安装用于快速连接阀注入过程的阀输送管。

    PROSTHETIC HEART VALVE PACKAGING AND DEPLOYMENT SYSTEM
    9.
    发明申请
    PROSTHETIC HEART VALVE PACKAGING AND DEPLOYMENT SYSTEM 有权
    前置心脏瓣膜包装和部署系统

    公开(公告)号：US20110147251A1

    公开(公告)日：2011-06-23

    申请号：US12969238

    申请日：2010-12-15

    申请人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    发明人： Fred Hodshon ,  Rafael Pintor ,  August Yambao ,  Abhishek Gautam ,  Louis A. Campbell ,  Lawrence Farhat ,  Tammy Huntley ,  Faisal Kalam ,  Travis Oba ,  Qinggang Zeng

    IPC分类号： B65D85/00

    CPC分类号： A61F2/2427 ,  A61F2/0095 ,  A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2220/0075

    摘要： Packaging for prosthetic heart valves including an assembly for securely retaining a heart valve within a jar and facilitating retrieval therefrom. The assembly includes a packaging sleeve that fits closely within the jar and has a clip structure for securing a valve holder. Contrary to previous designs, in one embodiment the valve holder is directed downward into the jar, and the valve is retained with an inflow end upward. The valve may have flexible leaflets, and a leaflet parting member on the end of the shaft extends through the leaflets and couples with the valve holder. The assembly of the packaging sleeve, valve, and holder can then be removed from the jar and a valve delivery tube connected with the holder, or to the leaflet parting member. The packaging sleeve may be bifurcated into two halves connected at a living hinge to facilitate removal from around the valve/holder subassembly. The packaging system facilitates attachment of the valve delivery tube for use in a quick-connect valve implant procedure.

    摘要翻译： 用于假体心脏瓣膜的包装，包括用于将心脏瓣膜牢固地保持在罐内并有助于从其中取出的组件。 组件包括紧密地配合在罐内的包装套筒，并具有用于固定阀座的夹子结构。 与以前的设计相反，在一个实施例中，阀保持器向下指向罐中，并且阀向上保持流入端。 阀可以具有柔性小叶，并且在轴的端部上的小叶分离构件延伸穿过叶片并与阀座联接。 然后可以将包装套筒，阀和保持器的组件从罐中移除，以及与保持器连接的阀输送管，或者与叶片分离构件相连。 包装套筒可以分叉成在活动铰链处连接的两个半部，以便于从阀/支架子组件周围移除。 该包装系统便于安装用于快速连接阀注入过程的阀输送管。