Apparatus and systems for processing samples for analysis via ion mobility spectrometry
    1.
    发明申请
    Apparatus and systems for processing samples for analysis via ion mobility spectrometry 有权
    用于通过离子迁移谱法处理样品用于分析的装置和系统

    公开(公告)号:US20060163471A1

    公开(公告)日:2006-07-27

    申请号:US11241747

    申请日:2005-09-30

    IPC分类号: H01J49/00

    CPC分类号: H01J49/0404 G01N27/624

    摘要: The invention provides an interface assembly for delivering an ionized analyte from an ionization apparatus into an ion mobility spectrometer. This allows analysis of biological and non-biological samples, even non-volatile solids, via differential mobility spectrometry, without fragmentation of molecules. The invention also provides portable sample analysis systems that operate at ambient pressure. Systems of the invention may be used for high molecular weight species detection, for example, drinking water contaminants, pathogenic biological agents, bio-organic substances, non-biological material, peptides, proteins, oligonucleotides, polymers, bacteria, and hydrocarbons.

    摘要翻译: 本发明提供了一种用于将离子化分析物从电离装置输送到离子迁移谱仪中的界面组件。 这允许通过差示迁移谱分析生物和非生物样品,甚至非挥发性固体,而不会破坏分子。 本发明还提供在环境压力下操作的便携式样品分析系统。 本发明的系统可用于高分子量物种检测,例如饮用水污染物,致病生物制剂,生物有机物质,非生物材料,肽,蛋白质,寡核苷酸,聚合物,细菌和烃类。

    Alignment and autoregressive modeling of analytical sensor data from complex chemical mixtures
    6.
    发明申请
    Alignment and autoregressive modeling of analytical sensor data from complex chemical mixtures 审中-公开
    来自复杂化学混合物的分析传感器数据的对准和自回归建模

    公开(公告)号:US20060020401A1

    公开(公告)日:2006-01-26

    申请号:US11184624

    申请日:2005-07-19

    IPC分类号: G01N31/00

    CPC分类号: G01N30/8603 G01N30/8617

    摘要: The invention provides methods for aligning and filtering chromatograms representative of complex mixture samples. In one embodiment, the invention includes identifying and matching related peaks to determine a temporal offset, and applying a nonlinear temporal shift to account for the offset. In other embodiments, the invention provides methods for smoothing chromatographic data by application of an autoregressive filter to provide improved signal-to-noise ratio, data compression, and resolution. The alignment and filtering methods may be performed separately or combined. In certain embodiments, the invention provides improved chromatographic pattern recognition capability and improved classification of samples of complex chemical and/or biological mixtures.

    摘要翻译: 本发明提供了用于校准和过滤表示复杂混合物样品的色谱图的方法。 在一个实施例中,本发明包括识别和匹配相关峰值以确定时间偏移,以及应用非线性时间偏移来考虑偏移。 在其他实施方案中,本发明提供了通过应用自回归滤波器来平滑色谱数据以提供改善的信噪比,数据压缩和分辨率的方法。 对准和过滤方法可以单独执行或组合。 在某些实施方案中,本发明提供改进的色谱图案识别能力和复杂化学和/或生物混合物样品的改进分类。

    ORGANO-METALLIC HYBRID MATERIALS FOR MICRO- AND NANOFABRICATION
    7.
    发明申请
    ORGANO-METALLIC HYBRID MATERIALS FOR MICRO- AND NANOFABRICATION 审中-公开
    用于微观和纳米化学的有机金属混合材料

    公开(公告)号:US20100279228A1

    公开(公告)日:2010-11-04

    申请号:US12809890

    申请日:2008-12-19

    摘要: One embodiment of the present invention provides a photosensitive organo-metallic hybrid material which functions as both a structural material and a photoresist material. More specifically, this photosensitive organo-metallic hybrid material includes an organo-metallic compound comprised of at least one unsaturated double bond. The photosensitive organo-metallic hybrid material also includes a cross-linking agent comprised of at least two unsaturated double bonds capable of cross-linking the organo-metallic compound to form an organo-metallic hybrid material. Additionally, the photosensitive organo-metallic hybrid material includes a photoactive compound capable of absorbing exposure light during a photolithography process to form the photosensitive organo-metallic hybrid material.

    摘要翻译: 本发明的一个实施方案提供了用作结构材料和光致抗蚀剂材料的光敏有机金属混合材料。 更具体地,该感光性有机金属杂化材料包括由至少一个不饱和双键组成的有机金属化合物。 光敏有机金属杂化材料还包括由能够交联有机金属化合物形成有机金属杂化材料的至少两个不饱和双键的交联剂。 另外,光敏有机金属杂化材料包括能够在光刻工艺中吸收曝光光以形成光敏有机金属混合材料的光活性化合物。