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    CYCLOPENTA[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES
    1.
    发明申请
    CYCLOPENTA[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES 审中-公开
    环己烷[b] [1,4] DIAZEPINO [6,7,1-hi]吲哚和衍生物

    公开(公告)号：US20080009480A1

    公开(公告)日：2008-01-10

    申请号：US11837875

    申请日：2007-08-13

    申请人： Annmarie Sabb ,  Robert Vogel ,  James Nelson ,  Sharon Rosenzweig-Lipson ,  Gregory Welmaker ,  Joan Sabalski

    发明人： Annmarie Sabb ,  Robert Vogel ,  James Nelson ,  Sharon Rosenzweig-Lipson ,  Gregory Welmaker ,  Joan Sabalski

    IPC分类号： A61K31/55 ,  A61P25/28

    CPC分类号： C07D209/94 ,  A61K31/55 ,  C07D487/06

    摘要： This invention provides compounds of the formulae: wherein: R1 is hydrogen, —C(O)CH3 or alkyl of 1-6 carbon atoms; R2 and R3 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, cycloalkyl, alkoxy of 1-6 carbon atoms, —CH2OH, fluoroalkyl, alkyl sulfonamide of 1-6 carbon atoms, alkyl amide of 1-6 carbon atoms, amino, alkylamino of 1-6 carbon atoms, dialkylamino of 1-6 carbon atoms per alkyl moiety, fluoroalkoxy of 1-6 carbon atoms, acyl of 2-7 carbon atoms, aryl, or aroyl; R4 and R5 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, halogen, fluoroalkyl, —CN, alkyl sulfonamide of 1-6 carbon atoms, alkyl amide of 1-6 carbon atoms, amino, alkylamino of 1-6 carbon atoms, dialkylamino of 1-6 carbon atoms per alkyl moiety, fluoroalkoxy of 1-6 carbon atoms, acyl of 2-7 carbon atoms, or aroyl; R6 and R7 are each independently hydrogen, C1-C6 alkyl or cycloalkyl; or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions containing these compounds and methods for their use, including treatment of obsessive-compulsive disorder, panic disorder, depression, anxiety, generalized anxiety disorder, schizophrenia, migraine, sleep disorders, eating disorders, obesity, epilepsy, and spinal cord injury.

    摘要翻译： 本发明提供下式的化合物：其中：R 1是氢，-C（O）CH 3或1-6个碳原子的烷基; R 2和R 3各自独立地为氢，1-6个碳原子的烷基，环烷基，1-6个碳原子的烷氧基，-CH 2 1-6个碳原子的烷基磺酰胺，1-6个碳原子的烷基酰胺，1-6个碳原子的烷基氨基，1-6个碳原子的烷基氨基，每个烷基部分1-6个碳原子的二烷基氨基，1个碳原子的氟代烷氧基 -6个碳原子，2-7个碳原子的酰基，芳基或芳酰基; R 4和R 5各自独立地为氢，1-6个碳原子的烷基，1-6个碳原子的烷氧基，卤素，氟烷基，-CN，烷基 1-6个碳原子的磺酰胺，1-6个碳原子的烷基酰胺，1-6个碳原子的烷基氨基，每个烷基部分1-6个碳原子的二烷基氨基，1-6个碳原子的氟烷氧基，2- 7个碳原子或芳酰基; R 6和R 7各自独立地为氢，C 1 -C 6烷基或环烷基; 或其药学上可接受的盐，以及含有这些化合物的药物组合物及其使用方法，包括治疗强迫症，恐慌症，抑郁症，焦虑症，广泛性焦虑症，精神分裂症，偏头痛，睡眠障碍，进食障碍， 肥胖，癫痫和脊髓损伤。

    Cyclopenta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives
    2.
    发明申请
    Cyclopenta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives 失效
    环戊基[b] [1,4]二氮杂[6,7,1-hi]吲哚及其衍生物

    公开(公告)号：US20050004101A1

    公开(公告)日：2005-01-06

    申请号：US10898029

    申请日：2004-07-23

    申请人： Annmarie Sabb ,  Robert Vogel ,  James Nelson ,  Sharon Rosenzweig-Lipson ,  Gregory Welmaker ,  Joan Sabalski

    发明人： Annmarie Sabb ,  Robert Vogel ,  James Nelson ,  Sharon Rosenzweig-Lipson ,  Gregory Welmaker ,  Joan Sabalski

    IPC分类号： A61K31/551 ,  A61K31/5517 ,  A61P3/04 ,  A61P25/00 ,  A61P25/06 ,  A61P25/08 ,  A61P25/18 ,  A61P25/22 ,  A61P25/24 ,  C07D209/00 ,  C07D209/94 ,  C07D243/00 ,  C07D487/06 ,  A61K31/55

    CPC分类号： C07D209/94 ,  A61K31/55 ,  C07D487/06

    摘要： This invention provides compounds of the formulae: wherein: R1 is hydrogen, —C(O)CH3 or alkyl of 1-6 carbon atoms; R2 and R3 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, cycloalkyl, alkoxy of 1-6 carbon atoms, —CH2OH, fluoroalkyl, alkyl sulfonamide of 1-6 carbon atoms, alkyl amide of 1-6 carbon atoms, amino, alkylamino of 1-6 carbon atoms, dialkylamino of 1-6 carbon atoms per alkyl moiety, fluoroalkoxy of 1-6 carbon atoms, acyl of 2-7 carbon atoms, aryl, or aroyl; R4 and R5 are each, independently, hydrogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, halogen, fluoroalkyl, —CN, alkyl sulfonamide of 1-6 carbon atoms, alkyl amide of 1-6 carbon atoms, amino, alkylamino of 1-6 carbon atoms, dialkylamino of 1-6 carbon atoms per alkyl moiety, fluoroalkoxy of 1-6 carbon atoms, acyl of 2-7 carbon atoms, or aroyl; R6 and R7 are each independently hydrogen, C1-C6 alkyl or cycloalkyl; or a pharmaceutically acceptable salt thereof, as well as pharmaceutical compositions containing these compounds and methods for their use, including treatment of obsessive-compulsive disorder, panic disorder, depression, anxiety, generalized anxiety disorder, schizophrenia, migraine, sleep disorders, eating disorders, obesity, epilepsy, and spinal cord injury.

    摘要翻译： 本发明提供下式的化合物：其中：R 1是氢，-C（O）CH 3或1-6个碳原子的烷基; R2和R3各自独立地为氢，1-6个碳原子的烷基，环烷基，1-6个碳原子的烷氧基，-CH2OH，氟代烷基，1-6个碳原子的烷基磺酰胺，1-6个碳原子的烷基酰胺 ，1-6个碳原子的氨基，烷基氨基，每个烷基部分1-6个碳原子的二烷基氨基，1-6个碳原子的氟烷氧基，2-7个碳原子的酰基，芳基或芳酰基; R4和R5各自独立地为氢，1-6个碳原子的烷基，1-6个碳原子的烷氧基，卤素，氟烷基，-CN，1-6个碳原子的烷基磺酰胺，1-6个碳原子的烷基酰胺 ，氨基，1-6个碳原子的烷基氨基，每个烷基部分1-6个碳原子的二烷基氨基，1-6个碳原子的氟烷氧基，2-7个碳原子的酰基或芳酰基; R6和R7各自独立地为氢，C1-C6烷基或环烷基; 或其药学上可接受的盐，以及含有这些化合物的药物组合物及其使用方法，包括治疗强迫症，恐慌症，抑郁症，焦虑症，广泛性焦虑症，精神分裂症，偏头痛，睡眠障碍，进食障碍， 肥胖，癫痫和脊髓损伤。

    Uniform resource locator access management and control system and method
    4.
    发明申请
    Uniform resource locator access management and control system and method 有权

    公开(公告)号：US20060095779A9

    公开(公告)日：2006-05-04

    申请号：US10127898

    申请日：2002-04-22

    申请人： Shivaram Bhat ,  James Nelson

    发明人： Shivaram Bhat ,  James Nelson

    IPC分类号： H04L9/00

    CPC分类号： H04L63/102 ,  H04L67/02

    摘要： In an enterprise server environment having a uniform resource locator (URL) access management and control system. The server includes a user authentication logic to authenticate users attempting to connect to the server to access URL file and directories residing in the server. In one embodiment of the present invention, the user is provided with an identification token and a user URL access policy which allows the user's credentials to be validated and permitted access to a list of URLs in the directory server. In one embodiment of the present invention, a URL access enforcement logic uses the user's URL access policy to determine which URLs in the directory server a user may or may not access. The user's URL access policy may include an access deny or an access allow value which respectively denies or allows the user access to particular URL.

    Screed heating arrangement
    5.
    发明申请
    Screed heating arrangement 审中-公开
    熨平板采暖布置

    公开(公告)号：US20060045624A1

    公开(公告)日：2006-03-02

    申请号：US11261001

    申请日：2005-10-28

    申请人： James Nelson

    发明人： James Nelson

    IPC分类号： E01C23/14

    CPC分类号： E01C19/407 ,  E01C19/4833 ,  E01C2301/10

    摘要： A screed heating arrangement is provided for a screed assembly that is towed behind a paving machine. The screed heating arrangement includes at least one electric heater bonded to an upper surface of a screed plate.

    摘要翻译： 为熨平板组件提供熨平板加热装置，其被拖曳在铺路机后面。 熨平板加热装置包括结合到熨平板上表面的至少一个电加热器。

    Variable volume container
    6.
    发明授权
    Variable volume container 有权
    可变容积容器

    公开(公告)号：US09346610B2

    公开(公告)日：2016-05-24

    申请号：US14169403

    申请日：2014-01-31

    申请人： James Nelson

    发明人： James Nelson

    IPC分类号： B65D88/46 ,  B65D88/44 ,  B65D41/32 ,  B65D85/72 ,  B65D81/20

    CPC分类号： B65D85/72 ,  B65D81/2015

    摘要： A variable volume container comprises a sidewall, a base having a ribbed region, and a diaphragm. The ribbed region has a plurality of concentric ribs extending from the diaphragm, and flexure zones between each rib. The flexure zones allow for accordion-like movement of the diaphragm in response to the internal pressure of the container. The ribs are characterized has having a uniformly arced interior curved surface and a distorted arced exterior curved surface. The ribs are four to eight times the width of the flexure zones, and the flexure zones have an exterior surface shorter than its bottom surface. During vacuum sealing, these features allow the diaphragm to retract upward to reduce the volume of the container while maintaining shape and structural stability of the container. This is especially useful for food packaging operations where containers need to be able to withstand conditions such as high pressure, heat, and/or vacuums.

    摘要翻译： 可变体积容器包括侧壁，具有肋状区域的基部和隔膜。 肋状区域具有从隔膜延伸的多个同心肋，并且在每个肋之间弯曲区域。 挠曲区允许响应于容器的内部压力的隔膜的类似手风琴的运动。 肋的特征在于具有均匀弧形的内部弯曲表面和变形的弧形外部曲面。 肋条是弯曲区域宽度的四至八倍，弯曲区域的外表面比其底面短。 在真空密封期间，这些特征允许膜片向上缩回以减小容器的体积，同时保持容器的形状和结构稳定性。 这对于容器需要能够承受诸如高压，热和/或真空的条件的食品包装操作特别有用。

    Telescoping plunger assembly
    8.
    发明申请
    Telescoping plunger assembly 审中-公开
    伸缩式活塞组件

    公开(公告)号：US20070005075A1

    公开(公告)日：2007-01-04

    申请号：US11322067

    申请日：2005-12-28

    申请人： Roy Bogert ,  James Nelson

    发明人： Roy Bogert ,  James Nelson

    IPC分类号： A61F2/00

    CPC分类号： B01F13/0023 ,  A61B17/8822 ,  A61F2002/30405 ,  A61F2002/30601 ,  A61F2220/0025 ,  B01F7/0025 ,  B01F7/00416 ,  B01F13/002 ,  B01F15/00506 ,  B01F15/027 ,  B01F15/0278 ,  B01F2215/0029

    摘要： A bone filler mixing and delivery device includes a mixing section adapted to mix components to form bone filler. A syringe barrel is coupled to the mixing section and has an opening through which the bone filler can be dispensed. A controllable portal can be manipulated to open a flow path between the mixing section and the syringe barrel. A plunger assembly is adapted to extend telescopically in an axial direction through the syringe barrel to dispense the bone filler through the opening.

    摘要翻译： 骨填料混合和递送装置包括适于混合组分以形成骨填料的混合部分。 注射器筒联接到混合部分并且具有可以分配骨填料的开口。 可以操纵可控入口以打开混合部分和注射器筒之间的流动路径。 柱塞组件适于沿轴向可伸缩地延伸穿过注射器筒，以通过开口分配骨填料。

    Gun stock pivot
    10.
    发明申请
    Gun stock pivot 失效
    枪库存枢纽

    公开(公告)号：US20050268516A1

    公开(公告)日：2005-12-08

    申请号：US10860685

    申请日：2004-06-03

    申请人： James Nelson

    发明人： James Nelson

    IPC分类号： F41C23/00 ,  F41C23/16 ,  F41G1/00

    CPC分类号： F41G1/00 ,  F41C23/16

    摘要： A mechanism, which may be integral with the gun parts or may be manufactured as an after-market item, which permits the butt of a shoulder-fired weapon to be pivoted about an axis substantially parallel to the axis of the gun barrel.

    摘要翻译： 可以与枪部分成一体的机构，或者可以作为售后市场物品制造，其允许肩部式武器的屁股围绕基本上平行于枪管的轴线的轴线枢转。