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公开(公告)号：US20160280723A1
公开(公告)日：2016-09-29
申请号：US15033004
申请日：2014-10-28
Inventor： Peiming Zhang , Subhadip Senapati , Saikat Manna
IPC: C07F7/18 , C07C317/28 , G01Q70/18 , C12N15/115 , C07K5/12 , C07F7/04 , C07C315/00
CPC classification number: C07F7/1804 , C07C315/00 , C07C317/28 , C07F7/045 , C07F7/10 , C07F7/1876 , C07K5/126 , C12N15/115 , C12N2310/16 , C12N2310/351 , C12N2310/3517 , G01Q60/42 , G01Q70/18
Abstract: Chemical linkage reagents, methods of making and method of using the same are provided. Chemical linkage reagents according to at least some of the embodiments of the present disclosure may be incorporated into or operatively-linked with affinity molecules for attachment to silicon oxide surfaces to, for example, measure interactions between an affinity molecule and its targeting biomolecules.
Abstract translation: 提供了化学键合试剂，制备方法及其使用方法。 根据本公开的至少一些实施方案的化学连接试剂可以并入或与活性连接的亲和分子连接到氧化硅表面以例如测量亲和分子与其靶向生物分子之间的相互作用。
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公开(公告)号：US10287257B2
公开(公告)日：2019-05-14
申请号：US15308517
申请日：2015-05-07
Inventor： Peiming Zhang , Stuart Lindsay , Saikat Manna , Subhadip Senapati
IPC: C07D249/04 , C07D249/06 , C07D491/052 , C07D487/04 , C07C247/04 , C07K14/00 , C12N15/115
Abstract: Some of the embodiments of the present disclosure relate to a compound of the formula, and methods of preparing and using same.
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公开(公告)号：US10156572B2
公开(公告)日：2018-12-18
申请号：US15119549
申请日：2015-02-18
Inventor： Peiming Zhang , Stuart Lindsay , Subhadip Senapati , Sudipta Biswas
IPC: C12Q1/68 , G01N33/58 , C07C247/04 , C07D495/04 , C12Q1/6816 , C12Q1/6834 , G01Q60/38
Abstract: Embodiments of the present disclosure provide bisbiotin ligands and related conjugates and methods. The bisbiotin ligands, combined with streptavidin, can be used in the separation, labelling, targeting, and immobilization of biomolecules.
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公开(公告)号：US09981997B2
公开(公告)日：2018-05-29
申请号：US15033004
申请日：2014-10-28
Inventor： Peiming Zhang , Subhadip Senapati , Saikat Manna
IPC: C07C317/00 , C07C247/04 , C07F7/18 , C07F7/10 , C07C315/00 , C07C317/28 , C07F7/04 , C07K5/12 , C12N15/115 , G01Q70/18 , G01Q60/42
CPC classification number: C07F7/1804 , C07C315/00 , C07C317/28 , C07F7/045 , C07F7/10 , C07F7/1876 , C07K5/126 , C12N15/115 , C12N2310/16 , C12N2310/351 , C12N2310/3517 , G01Q60/42 , G01Q70/18
Abstract: Chemical linkage reagents, methods of making and method of using the same are provided. Chemical linkage reagents according to at least some of the embodiments of the present disclosure may be incorporated into or operatively-linked with affinity molecules for attachment to silicon oxide surfaces to, for example, measure interactions between an affinity molecule and its targeting biomolecules.
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