公开(公告)号：US20090095635A1

公开(公告)日：2009-04-16

申请号：US12176296

申请日：2008-07-18

申请人： Arkadij M. Elizarov ,  Hartmuth C. Kolb ,  R. Michael van Dam ,  James R. Heath ,  Brian Edgecombe ,  Farshad Motamedi ,  Anthony Stephen ,  Michael A. Giardello

发明人： Arkadij M. Elizarov ,  Hartmuth C. Kolb ,  R. Michael van Dam ,  James R. Heath ,  Brian Edgecombe ,  Farshad Motamedi ,  Anthony Stephen ,  Michael A. Giardello

IPC分类号： C25B3/08

CPC分类号： C07B59/00

摘要： Methods and apparatus enable radiosynthesis of radiolabeled compounds using electrochemical trapping and release. The trapping and release of radioactive isotopes all occur inside a microreactor, a vial or similar device, thus eliminating the need for azeotropic drying and several dead-end filling steps, as well as the necessity to move concentrated radioisotopes from one compartment of the chip to another. These and other features allow radioisotope enrichment to be carried out internally within a radiochemical synthesis chip, providing faster and more robust operation, as well as producing very high radiochemical labeling yields.

摘要翻译： 方法和装置能够使用电化学捕获和释放来放射性标记化合物的放射合成。 放射性同位素的捕获和释放都发生在微反应器，小瓶或类似装置内，因此不需要共沸干燥和几个死端填充步骤，以及将浓缩放射性同位素从芯片的一个室移动到 另一个。 这些和其他特征允许放射性同位素富集在放射化学合成芯片内部进行，提供更快和更强的操作，以及产生非常高的放射化学标记产率。

公开(公告)号：US20060052487A1

公开(公告)日：2006-03-09

申请号：US11260754

申请日：2005-10-26

申请人： Christopher Cruce ,  Gary Filice ,  Michael Giardello ,  Anthony Stephen ,  Mark Trimmer

发明人： Christopher Cruce ,  Gary Filice ,  Michael Giardello ,  Anthony Stephen ,  Mark Trimmer

IPC分类号： C08K3/00

CPC分类号： C08L65/00 ,  C04B41/009 ,  C04B41/4857 ,  C04B41/63 ,  C04B2111/27 ,  C08J9/42 ,  C08J2423/00 ,  C08K3/01 ,  C08K5/098 ,  C08K5/5425 ,  C08L23/02 ,  C08L79/02 ,  C08L97/02 ,  Y10T428/249925 ,  C04B41/4521 ,  C04B28/02 ,  C08L2666/26 ,  C08L2666/02 ,  C08L2666/22 ,  C08L2666/06

摘要： The present invention relates to novel compositions comprising porous materials infused with polymers obtained from metathesis reactions, for example ROMP derived polymers and ADMET derived polymers. The invention further relates to cyclic olefin monomer formulations, including ruthenium or osmium carbene metathesis catalysts, useful for the infusion of porous materials. Also disclosed are methods for preparing the porous materials infused with cyclic olefin resin formulations.