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1.发明申请PULSATILE DELIVERY OF GONADOTROPIN-RELEASING HORMONE FROM A PRE-LOADED INTEGRATED ELECTROTRANSPORT PATCH 审中-公开从预加载的集成电子邮件传送中释放激肽释放激素的药物公开(公告)号：US20070078373A1
公开(公告)日：2007-04-05
申请号：US11537308
申请日：2006-09-29
申请人： Ashutosh Sharma , Sonal Patel , Vilambi Reddy , Preston Keusch , Yogeshvar Kalia
发明人： Ashutosh Sharma , Sonal Patel , Vilambi Reddy , Preston Keusch , Yogeshvar Kalia
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/0436 , A61N1/044
摘要： Provided are various embodiments of integrated electrode devices, assemblies and systems structured for use in association with electrically assisted delivery devices configured for delivery of a composition, such as a composition comprising gonadotropin-releasing hormone and/or related analogs through a membrane. The integrated electrode devices, assemblies and systems include one or more of a variety of structural, physical, mechanical, electrical and electromechanical enhancements. Methods of administering compositions to patients with integrated electrode devices according to various embodiments described herein are also disclosed.
摘要翻译： 提供了集成电极装置，组件和系统的各种实施例，其被构造用于与被配置用于递送组合物的电辅助递送装置结合使用，所述组合物例如包含通过膜的促性腺激素释放激素和/或相关类似物的组合物。 集成电极装置，组件和系统包括各种结构，物理，机械，电和机电增强中的一种或多种。 还公开了根据本文所述的各种实施方案向具有集成电极装置的患者施用组合物的方法。
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2.发明申请COSMETIC COMPOSITIONS CONTAINING POLYPROPYLSILSESQUIOXANE, A VOLATILE SOLVENT, BORON NITRIDE, AND SILICA 有权含有聚丙烯酰胺，挥发性溶剂，硝酸硼和二氧化硅的化妆品组合物公开(公告)号：US20110243867A1
公开(公告)日：2011-10-06
申请号：US13076924
申请日：2011-03-31
申请人： Sonal Patel , Ashini Amin , Lisa Voorhees-Nordhaus
发明人： Sonal Patel , Ashini Amin , Lisa Voorhees-Nordhaus
CPC分类号： A61Q1/10 , A61K8/0241 , A61K8/19 , A61K8/25 , A61K8/891 , A61K2800/412 , A61K2800/592
摘要： Disclosed are cosmetic compositions containing a polypropylsilsesquioxane, a volatile solvent, boron nitride, and silica. Also disclosed are methods for making the cosmetic compositions and applying them to keratinous tissue such as skin in order to enhance its appearance.
摘要翻译： 公开了含有聚丙基硅倍半氧烷，挥发性溶剂，氮化硼和二氧化硅的化妆品组合物。 还公开了制备化妆品组合物并将其施用于角质组织如皮肤的方法，以增强其外观。
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3.发明申请COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE 有权磷酸三辛酯抑制剂化合物和化学治疗剂的组合及使用方法公开(公告)号：US20110223619A1
公开(公告)日：2011-09-15
申请号：US13109670
申请日：2011-05-17
申请人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
发明人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
IPC分类号： G01N33/574 , C12Q1/02
CPC分类号： A61K31/5377 , A61K31/4523 , A61K31/505
摘要： Combinations of PI3K inhibitor compounds having Formulas I and II and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
摘要翻译： 具有式I和II的PI3K抑制剂化合物的组合和化学治疗剂，包括立体异构体，几何异构体，互变异构体，代谢物及其药学上可接受的盐，可用于治疗过度增殖性疾病如癌症。 公开了将这些组合用于体外，原位和体内诊断，预防或治疗哺乳动物细胞或相关病理条件中的这种疾病的方法。
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公开(公告)号：US07300765B2
公开(公告)日：2007-11-27
申请号：US10509975
申请日：2003-04-02
申请人： Sonal Patel
发明人： Sonal Patel
IPC分类号： G01N33/574 , G01N33/53 , A61K39/00
CPC分类号： C07K14/47 , A61K38/00 , G01N33/574 , G01N33/68 , G01N2800/52
摘要： The present invention relates to new uses of Solute Carrier 6 (SC6), a taurine transporter, in the diagnosis, screening, treatment and prophylaxis of hypoxia related conditions e.g. cancer. Compositions comprising the protein, such as vaccines and agents that modulate the protein expression or activity, including antibodies that are immunospecific for the protein, are also provided.
摘要翻译： 本发明涉及溶氧载体6（SC6），一种牛磺酸转运蛋白在诊断，筛选，治疗和预防缺氧相关病症中的新用途，例如， 癌症。 还提供了包含蛋白质的组合物，例如调节蛋白质表达或活性的疫苗和试剂，包括对蛋白质具有免疫特异性的抗体。
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公开(公告)号：US20080305068A1
公开(公告)日：2008-12-11
申请号：US11810559
申请日：2007-06-06
申请人： Tao Zheng , Leona G. Fleissman , Maha Raouf , Sonal Patel
发明人： Tao Zheng , Leona G. Fleissman , Maha Raouf , Sonal Patel
摘要： Cosmetic compositions and methods with improved transfer resistance and long wear properties are disclosed. The cosmetic compositions contain a synergistic combination of at least one silicone polyurethane polymer and at least one elastomer.
摘要翻译： 公开了具有改善的耐转移性和长的耐磨性的化妆品组合物和方法。 化妆品组合物含有至少一种硅氧烷聚氨酯聚合物和至少一种弹性体的协同组合。
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公开(公告)号：US08277791B2
公开(公告)日：2012-10-02
申请号：US11810559
申请日：2007-06-06
申请人： Tao Zheng , Leona G. Fleissman , Maha Raouf , Sonal Patel
发明人： Tao Zheng , Leona G. Fleissman , Maha Raouf , Sonal Patel
摘要： Cosmetic compositions and methods with improved transfer resistance and long wear properties are disclosed. The cosmetic compositions contain a synergistic combination of at least one silicone polyurethane polymer and at least one elastomer.
摘要翻译： 公开了具有改善的耐转移性和长的耐磨性的化妆品组合物和方法。 化妆品组合物含有至少一种硅氧烷聚氨酯聚合物和至少一种弹性体的协同组合。
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7.发明申请COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE 有权磷酸三辛酯抑制剂化合物和化学治疗剂的组合及使用方法公开(公告)号：US20090098135A1
公开(公告)日：2009-04-16
申请号：US12208227
申请日：2008-09-10
申请人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
发明人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
IPC分类号： A61K31/5377 , A61P35/00 , A61K31/7068 , A61K33/24 , A61K39/395 , A61K31/704 , C12Q1/48
CPC分类号： A61K31/5377 , A61K31/4523 , A61K31/505
摘要： Combinations of PI3K inhibitor compounds having Formulas I and II and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
摘要翻译： 具有式I和II的PI3K抑制剂化合物的组合和化学治疗剂，包括立体异构体，几何异构体，互变异构体，代谢物及其药学上可接受的盐，可用于治疗过度增殖性疾病如癌症。 公开了将这些组合用于体外，原位和体内诊断，预防或治疗哺乳动物细胞或相关病理条件中的这种疾病的方法。
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公开(公告)号：US20060292616A1
公开(公告)日：2006-12-28
申请号：US11474067
申请日：2006-06-23
申请人： Lori Neely , Sonal Patel
发明人： Lori Neely , Sonal Patel
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/158 , C12Q2600/178
摘要： The invention relates to compositions and methods for detecting and quantifying small RNA species such as miRNA, preferably associated with disease detection and diagnosis.
摘要翻译： 本发明涉及用于检测和定量miRNA的miRNA的组合物和方法，优选与疾病检测和诊断有关。
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9.发明授权Combinations of phosphoinositide 3-kinase inhibitor compounds chemotherapeutic agents, and methods of use 有权磷酸肌醇3-激酶抑制剂化合物化疗剂的组合及使用方法公开(公告)号：US08604014B2
公开(公告)日：2013-12-10
申请号：US13109670
申请日：2011-05-17
申请人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
发明人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
CPC分类号： A61K31/5377 , A61K31/4523 , A61K31/505
摘要： Combinations of PI3K inhibitor compounds having Formulas I and II and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
摘要翻译： 具有式I和II的PI3K抑制剂化合物的组合和化学治疗剂，包括立体异构体，几何异构体，互变异构体，代谢物及其药学上可接受的盐，可用于治疗过度增殖性疾病如癌症。 公开了将这些组合用于体外，原位和体内诊断，预防或治疗哺乳动物细胞或相关病理条件中的这种疾病的方法。
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10.发明授权Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents, and methods of use 有权磷酸肌醇3-激酶抑制剂化合物和化学治疗剂的组合以及使用方法公开(公告)号：US08247397B2
公开(公告)日：2012-08-21
申请号：US12208227
申请日：2008-09-10
申请人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
发明人： Marcia Belvin , Lori Friedman , Klaus Hoeflich , Deepak Sampath , Ulka Vijapurkar , Jeffrey Wallin , Leisa Johnson , Mallika Singh , Sonal Patel
IPC分类号： A61K31/33
CPC分类号： A61K31/5377 , A61K31/4523 , A61K31/505
摘要： Combinations of PI3K inhibitor compounds having Formulas I and II and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
摘要翻译： 具有式I和II的PI3K抑制剂化合物的组合和化学治疗剂，包括立体异构体，几何异构体，互变异构体，代谢物及其药学上可接受的盐，可用于治疗过度增殖性疾病如癌症。 公开了将这些组合用于体外，原位和体内诊断，预防或治疗哺乳动物细胞或相关病理条件中的这种疾病的方法。
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