公开(公告)号：US10717973B2

公开(公告)日：2020-07-21

申请号：US16212287

申请日：2018-12-06

Applicant: BASF SE

Inventor： Michael Breuer ,  Bernhard Hauer ,  Dieter Jendrossek ,  Gabriele Siedenburg ,  Juergen Pleiss ,  Demet Sirim ,  Silvia Fadenrecht

IPC: C12P7/22 ,  C12P7/02 ,  C12N9/88 ,  C12N9/90 ,  C12P5/00

Abstract: The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.

公开(公告)号：US10190112B2

公开(公告)日：2019-01-29

申请号：US15234529

申请日：2016-08-11

Applicant: BASF SE

Inventor： Michael Breuer ,  Bernhard Hauer ,  Dieter Jendrossek ,  Gabriele Siedenburg ,  Juergen Pleiss ,  Demet Sirim ,  Silvia Fadenrecht

IPC: C12N9/88 ,  C12N9/10 ,  C12N15/00 ,  C12P7/02 ,  C12P5/00 ,  C12N9/90 ,  C12P7/22

Abstract: The present invention relates to novel mutants with cyclase activity and use thereof in a method for biocatalytic cyclization of terpenes, such as in particular for the production of isopulegol by cyclization of citronellal; a method for the preparation of menthol and methods for the biocatalytic conversion of further compounds with structural motifs similar to terpene.