公开(公告)号：US20240109838A1

公开(公告)日：2024-04-04

申请号：US18265999

申请日：2021-12-16

Applicant: BASF SE

Inventor： Karin SCHEIN-ALBRECHT ,  Thomas EHLIS ,  Mathieu BLANCHOT ,  Dennis KAUFHOLD ,  Helmut KRONEMAYER ,  Sebastian WLOCH

IPC: C07C227/18 ,  C07C227/10 ,  C07C227/40 ,  C07C227/42 ,  C07C229/52

CPC classification number: C07C227/18 ,  C07C227/10 ,  C07C227/40 ,  C07C227/42 ,  C07C229/52

Abstract: The present invention relates to a process of manufacturing 2-(4′-diethylamino-2′-hydroxybenzoyl)benzoic acid hexyl ester having a Gardner value of 8.2 or less comprising adjusting the reaction mixture obtained by reacting 2-(4′-diethylamino-2′-hydroxybenzoyl)benzoic acid with n-hexanol to a pH of more than 7 followed by extracting at least once with an aqueous phase and adsorbing the dissolved 2-(4′-diethylamino-2′-hydroxybenzoyl)benzoic acid hexyl ester over at least two different adsorbents.

公开(公告)号：US20240150276A1

公开(公告)日：2024-05-09

申请号：US18279899

申请日：2022-03-01

Applicant: BASF SE

Inventor： Daniel Ruben SELZER ,  Eva KLEINMANN ,  Axel BINDER ,  Helmut KRONEMAYER ,  Philipp STAEHLE

IPC: C07C229/52

CPC classification number: C07C229/52

Abstract: The present invention relates to a process for the solidification of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate, DHHB), wherein the process comprises the step of (a) applying a shear rate of 800 s−1 or more to liquid hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate and (b) adding seed crystals of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate.

公开(公告)号：US20230357129A1

公开(公告)日：2023-11-09

申请号：US17802171

申请日：2021-02-25

Applicant: BASF SE

Inventor： Thomas EHLIS ,  Karin SCHEIN-ALBRECHT ,  Mathieu BLANCHOT ,  Dennis KAUFHOLD ,  Sebastian WLOCH ,  Helmut KRONEMAYER

IPC: C07C227/42 ,  C07C229/52

CPC classification number: C07C227/42 ,  C07C229/52 ,  C07B2200/13

Abstract: The present invention relates to a process for isolating 2-(4′-diethylamino-2′-hydroxybenzoyl)benzoic acid hexyl ester with a high purity and low phthalic acid dialkyl ester content.

公开(公告)号：US20240140906A1

公开(公告)日：2024-05-02

申请号：US18279902

申请日：2022-03-01

Applicant: BASF SE

Inventor： Daniel Ruben SELZER ,  Eva KLEINMANN ,  Axel BINDER ,  Helmut KRONEMAYER ,  Philipp STAEHLE

IPC: C07C227/42 ,  B01D9/00

CPC classification number: C07C227/42 ,  B01D9/0036

Abstract: The present invention relates to a process for the solidification of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate (INCI diethylamino hydroxybenzoyl hexyl benzoate, DHHB), wherein the process comprises the step of (a) applying a shear rate of less than 800 s−1 to liquid hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate and (b) adding seed crystals of hexyl 2-[4-(diethylamino)-2-hydroxybenzoyl]benzoate.

公开(公告)号：US20170015608A1

公开(公告)日：2017-01-19

申请号：US15124944

申请日：2015-03-05

Applicant: BASF SE

Inventor： Rolf PINKOS ,  Nicolas MARION ,  Helmut KRONEMAYER

IPC: C07C29/141

CPC classification number: C07C29/141 ,  C07C29/90 ,  C07C31/20

Abstract: A process for decomposing formates in formate-containing compositions of matter comprises reacting formate-containing compositions of matter in the presence of at least one heterogeneous catalyst comprising lanthanum and at a temperature of from 80 to 180° C. and a pressure of from 0.1 to 60 bar, the formate-containing compositions of matter having a pH of from 6.5 to 10

Abstract translation: 在含甲酸盐的物质组合物中分解甲酸盐的方法包括在至少一种包含镧的非均相催化剂存在下，含有含甲酸盐的物质组合物，在80-180℃的温度和0.1至 60巴，含有甲酸盐的组合物，其pH为6.5至10

公开(公告)号：US20250066312A1

公开(公告)日：2025-02-27

申请号：US18726838

申请日：2022-12-20

Applicant: BASF SE

Inventor： Christian SCHWEDE ,  Johannes Felix HAUS ,  Joerg THERRE ,  Jacek MALISZ ,  Helmut KRONEMAYER ,  Matthias KRUCK ,  Markus SPITTLER

IPC: C07D251/24

Abstract: The present invention relates to an improved process for isolating 2,4-bis-(2,4-dihydroxyphenyl)-6-(4-methoxyphenyl)-1,3,5-triazine (DIOPAT) from a DIOPAT-containing aqueous mixture N, wherein the process comprises the steps of concentrating the aqueous mixture N to obtain a DIOPAT-containing aqueous suspension S1 having a certain solid content; evaporating solvent from the aqueous suspension S1; and drying the DIOPAT to obtain a solid content of more than 90 wt.-%, based on the total weight of the DIOPAT.

公开(公告)号：US20240025841A1

公开(公告)日：2024-01-25

申请号：US18265993

申请日：2021-12-16

Applicant: BASF SE

Inventor： Helmut KRONEMAYER ,  Sebastian WLOCH ,  Andreas MELZER ,  Mathieu BLANCHOT ,  Karin SCHEIN-ALBRECHT ,  Dennis KAUFHOLD ,  Thomas EHLIS

IPC: C07C227/42 ,  C07C227/16 ,  A61K8/41

CPC classification number: C07C227/42 ,  C07C227/16 ,  A61K8/411 ,  C07B2200/13

Abstract: The presently claimed invention relates to a method for obtaining crystalline diethylamino hydroxybenzoyl hexyl benzoate. Further, the presently claimed invention relates to crystalline diethylamino hydroxybenzoyl hexyl benzoate obtained by the method and to a cosmetic composition comprising crystalline diethylamino hydroxybenzoyl hexyl benzoate. The crystalline diethylamino hydroxybenzoyl hexyl benzoate obtained by the method of the presently claimed invention has a phthalic acid dihexyl ester (PSDHE) content in the range of 1 to 250 ppm.

公开(公告)号：US20230074079A1

公开(公告)日：2023-03-09

申请号：US17783670

申请日：2020-12-15

Applicant: BASF SE

Inventor： Miriam BRU ROIG ,  Florian GARLICHS ,  Manuel DANZ ,  Ralf PELZER ,  Helmut KRONEMAYER ,  Volker HICKMANN ,  Melanie WEINGARTEN

IPC: C07D309/06 ,  C07D319/06

Abstract: The present invention relates to substituted 4-methylene-tetrahydropyrans, 4-methyl-dihydropyrans and 4-methyl-tetrahydropyrans of formula (I), where the variables are as defined in the claims and description, to a stereoisomer thereof, to a mixture of stereoisomers thereof, to a mixture of different di- and tetrahydropyrans (I) and to a mixture containing at least one di- or tetrahydropyran (I) and at least one cyclic acetal which is a 1,3-dioxan carrying in 2-position an isobutanol-2-yl-(derived) substituent and in 4,4- or 5,5-position two methyl substituents. The invention also relates to the use of such compounds as an aroma chemical and/or for modifying and/or enhancing the aroma of a composition, to compositions comprising such compounds, to methods for preparing such compounds and to a product obtainable by these methods.