公开(公告)号：US09920019B2

公开(公告)日：2018-03-20

申请号：US14581761

申请日：2014-12-23

申请人： INSTITUTO MEXICANO DEL PETROLEO

发明人： Raul Hernandez Altamirano ,  Violeta Yasmin Mena Cervantes ,  Luis Silvestre Zamudio Rivera ,  Hiram Isaac Beltran Conde ,  Eduardo Buenrostro Gonzalez

IPC分类号： C09K8/54 ,  C07D265/10 ,  C09K8/524 ,  C10L1/14 ,  C10L1/233 ,  C10L10/00 ,  C10L10/04 ,  C10G75/02 ,  C07C227/10 ,  C10L1/16 ,  C10L1/182

CPC分类号： C07D265/10 ,  C07C227/10 ,  C09K8/524 ,  C09K8/54 ,  C10G75/02 ,  C10G2300/1033 ,  C10G2300/206 ,  C10G2300/4075 ,  C10G2300/44 ,  C10G2300/80 ,  C10G2400/02 ,  C10G2400/04 ,  C10G2400/08 ,  C10L1/14 ,  C10L1/1608 ,  C10L1/1616 ,  C10L1/1824 ,  C10L1/233 ,  C10L10/00 ,  C10L10/04 ,  C10L2200/0259 ,  C10L2200/0423 ,  C10L2200/043 ,  C10L2200/0446 ,  C10L2230/08 ,  C10L2230/14 ,  C10L2270/023 ,  C10L2270/04 ,  C10L2270/10

摘要： Base compounds including 1,3-oxazinan-6-one derivatives of N-alkyl or N-alkenyl or N-cycloalkyl or N-aryl propionic acids and paraformaldehyde, and their application as corrosion inhibitors with multifunctional properties serving as inhibitory/dispersant of asphaltene in production processes, transportation, refining and storage of crude oil and derivatives. The corrosion inhibitor with inhibitory/dispersant of asphaltenes properties comprises an active substance base of 1,3-oxaninan-6-ones and hydrocarbon solvents such as benzene, toluene, mixed xylenes, o-xylene, m-xylene and p-xylene, diesel, kerosene, jet fuel, alcohols, aliphatic branched and unbranched alcohols containing from 3 to 10 carbon atoms, such as isopropanol, butanol and pentanol, and mixtures of hydrocarbon solvents with aliphatic branched or unbranched liquid fuels. In addition, a process for obtaining 1,3-oxazinan-6-ones derivatives of N-alkyl or N-alkenyl or N-cycloalkyl or N-aryl propionic acids and paraformaldehyde is described.

公开(公告)号：US20180002274A1

公开(公告)日：2018-01-04

申请号：US15541769

申请日：2016-02-09

申请人： PIVERT S.A.S. ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) ,  UNIVERSITE D'ARTOIS

发明人： Frederic HAPIOT ,  Eric MONFLIER ,  Theodore VANBESIEN

IPC分类号： C07C229/12 ,  C07C227/10

CPC分类号： C07C229/12 ,  C07C227/10

摘要： The present invention relates to amino alcohol compounds and to the preparation thereof from fatty esters comprising at least two carbon-carbon double bonds. In particular, the present invention relates to fatty amino alcohol compounds obtained by means of a process coupling, in a single step, a hydroaminomethylation reaction and a hydrohydroxymethylation reaction.

公开(公告)号：US20170098773A1

公开(公告)日：2017-04-06

申请号：US15245969

申请日：2016-08-24

申请人： PHILLIPS 66 COMPANY

发明人： Joseph Bullock ,  Brian Worfolk

IPC分类号： H01L51/00 ,  C07C227/10 ,  C07C67/29

CPC分类号： H01L51/0047 ,  C07C67/29 ,  C07C213/06 ,  C07C227/10 ,  C07C2604/00 ,  H01L51/4253 ,  C07C219/22

摘要： A process of dissolving in a solvent to produce a first mixture. To the first mixture a reagent is added to produce a second mixture. A H—R′—R″ is then added to the second mixture to produce a third mixture. The third mixture is then refluxed to produce

公开(公告)号：US20170096388A1

公开(公告)日：2017-04-06

申请号：US15383635

申请日：2016-12-19

申请人： DUQUESNE UNIVERSITY OF THE HOLY GHOST

发明人： SURAVI CHAKRABARTY ,  DARLENE MONLISH ,  PATRICK FLAHERTY ,  JANE E. CAVANAUGH ,  SNEHA POTDAR

IPC分类号： C07C227/10

CPC分类号： C07C227/10 ,  C07C229/58

摘要： The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5.

公开(公告)号：US09079824B2

公开(公告)日：2015-07-14

申请号：US13808228

申请日：2011-07-06

申请人： Teck Peng Loh ,  Jiesheng Tian

发明人： Teck Peng Loh ,  Jiesheng Tian

IPC分类号： C07F7/10 ,  C07C211/00 ,  C07D209/48 ,  C07C213/08 ,  C07B41/04 ,  C07C213/00 ,  C07C227/18 ,  C07C227/10 ,  C07F7/18 ,  C07B59/00 ,  C07C213/02

CPC分类号： C07C213/08 ,  C07B41/04 ,  C07B59/001 ,  C07C213/00 ,  C07C213/02 ,  C07C227/10 ,  C07C227/18 ,  C07D209/48 ,  C07F7/1804 ,  C07F7/1892 ,  C07C217/40

摘要： The present invention relates to a method for the synthesis of an α amino acetal, comprising (i) oxidizing a tertiary amine in the presence of a copper catalyst, at least one oxidant and a solvent, or (ii) reacting a secondary amine and an aliphatic aldehyde in the presence of a copper catalyst, at least one oxidant and a solvent.

摘要翻译： 本发明涉及一种用于合成α氨基乙缩醛的方法，其包括（i）在铜催化剂，至少一种氧化剂和溶剂的存在下氧化叔胺，或（ii）使仲胺和 脂族醛在铜催化剂，至少一种氧化剂和溶剂的存在下进行。

公开(公告)号：US20150089861A1

公开(公告)日：2015-04-02

申请号：US14563234

申请日：2014-12-08

申请人： INSTITUTO MEXICANO DEL PETROLEO

发明人： Raul Hernandez Altamirano ,  Luis Silvestre Zamudio Rivera ,  Violeta Yasmin Mena Cervantes ,  Hiram Isaac Beltran Conde ,  Marco Antonio Dominguez Aguilar ,  Jaquelin Martinez Viramontes ,  Aristeo Estrada Buendia

IPC分类号： C10L10/04 ,  C09K15/20 ,  C07C227/10 ,  C07C229/12 ,  C10L1/222 ,  C07C229/24

CPC分类号： C07C227/16 ,  C07C227/10 ,  C07C227/26 ,  C07C229/12 ,  C07C229/16 ,  C07C229/24 ,  C09K15/20 ,  C10L1/143 ,  C10L1/1608 ,  C10L1/1616 ,  C10L1/1824 ,  C10L1/1985 ,  C10L1/2222 ,  C10L1/223 ,  C10L10/04 ,  C10L2200/0259 ,  C10L2200/0423 ,  C10L2200/043 ,  C10L2200/0446 ,  C10L2230/14 ,  C10L2270/023 ,  C10L2270/026 ,  C10L2270/04 ,  C10L2270/10 ,  C10L2300/20 ,  C23F11/143

摘要： N-alkyl, N-alkenyl, N-cycloalkyl, N-aryl amino or imino propionic acids with an alkyl chain ranging from 6 to 18 carbons, or alkenyl chain from 8 to 30 carbons, are obtained from a reaction process in the absence of solvent at a temperature range from 30 to 180° C. and a time of 1 to 10 hours at atmospheric pressure. Formulations composed of N-alkyl or N-alkenyl or N-cycloalkyl or N-aryl amino or imino propionic acids, polyethers derived from propylene oxide or ethylene oxide or copolymer thereof and a solvent consisting of aromatic compounds such as toluene or xylene, diesel or gasoline or alcohols such as isopropanol and ethanol, or mixtures thereof, are obtained inhibit ferrous metal corrosion of pipelines and storage tanks and transport crude oil and liquid fuels. A method inhibiting corrosion of ferrous metals adds an effective amount of the corrosion inhibitor to a petroleum based material such as crude oil and liquid fuels such as gasoline, diesel fuel, and aviation fuel.

公开(公告)号：US08796459B2

公开(公告)日：2014-08-05

申请号：US13619297

申请日：2012-09-14

申请人： Eric Dowdy ,  Xi Chen ,  Steven Pfeiffer

发明人： Eric Dowdy ,  Xi Chen ,  Steven Pfeiffer

IPC分类号： A61K31/47 ,  A61K31/4174 ,  A61K31/216 ,  C07D215/20 ,  C07D233/22 ,  C07C69/773

CPC分类号： C07D215/56 ,  C07C41/28 ,  C07C41/30 ,  C07C43/225 ,  C07C43/23 ,  C07C51/367 ,  C07C51/377 ,  C07C65/24 ,  C07C67/18 ,  C07C67/343 ,  C07C227/10 ,  C07C227/16 ,  C07C227/18 ,  C07D233/54 ,  C07D233/60 ,  C07C69/738 ,  C07C229/34

摘要： The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.

公开(公告)号：US20130116437A1

公开(公告)日：2013-05-09

申请号：US13619297

申请日：2012-09-14

申请人： Eric Dowdy ,  Xi Chen ,  Steven Pfeiffer

发明人： Eric Dowdy ,  Xi Chen ,  Steven Pfeiffer

IPC分类号： C07D215/56 ,  C07C227/18 ,  C07C67/18 ,  C07C227/10 ,  C07C51/377 ,  C07D233/60

CPC分类号： C07D215/56 ,  C07C41/28 ,  C07C41/30 ,  C07C43/225 ,  C07C43/23 ,  C07C51/367 ,  C07C51/377 ,  C07C65/24 ,  C07C67/18 ,  C07C67/343 ,  C07C227/10 ,  C07C227/16 ,  C07C227/18 ,  C07D233/54 ,  C07D233/60 ,  C07C69/738 ,  C07C229/34

摘要： The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.

公开(公告)号：US08324125B2

公开(公告)日：2012-12-04

申请号：US12553681

申请日：2009-09-03

申请人： Rajender S. Varma ,  Vivek Polshettiwar

发明人： Rajender S. Varma ,  Vivek Polshettiwar

IPC分类号： C07F15/04 ,  C07F15/06 ,  C07C321/04 ,  C07D207/323 ,  C07D401/06 ,  C07D207/325

CPC分类号： B01J31/0271 ,  B01J31/0228 ,  B01J31/0254 ,  B01J35/0033 ,  B01J37/0209 ,  C07C227/10 ,  C07C323/60 ,  C07D207/323 ,  C07D207/325 ,  C07D405/06 ,  C07C229/12 ,  C07C229/14 ,  C07C229/18

摘要： This invention relates to the use of nano-organocatalysts, and, more specifically, to the use of magnetic nanomaterial-supported organocatalysts. It is an object of the present invention to provide “green” catalysts and protocols. According to one embodiment of the invention, a nano-organocatalyst in the form of a magnetic nanomaterial-supported organocatalyst is provided. According to other embodiments of the invention, glutathione and cysteine are provided as organocatalysts and magnetic nanomaterial-supported glutathione and magnetic nanomaterial-supported cysteine are provided for use as nano-organocatalysts. According to another embodiment of the invention, a method of using a recyclable magnetic nanomaterial-supported organocatalyst using a totally benign aqueous protocol, without using any organic solvent in the reaction or during the workup, is provided. According to a further embodiment of the invention, a recyclable magnetic nanomaterial-supported organocatalyst for various organocatalytic reactions, including but not limited to Paal-Knorr reactions, aza-Michael addition and pyrazole synthesis, is provided.

摘要翻译： 本发明涉及纳米有机催化剂的用途，更具体地说，涉及使用磁性纳米材料负载的有机催化剂。 本发明的目的是提供绿色催化剂和方案。 根据本发明的一个实施方案，提供了纳米材料负载有机催化剂形式的纳米有机催化剂。 根据本发明的其它实施方案，提供谷胱甘肽和半胱氨酸作为有机催化剂，并提供磁性纳米材料负载的谷胱甘肽和磁性纳米材料负载的半胱氨酸用作纳米有机催化剂。 根据本发明的另一个实施方案，提供了使用完全良性水溶液方案使用可回收的磁性纳米材料负载的有机催化剂的方法，而不在反应中或在后处理中使用任何有机溶剂。 根据本发明的另一个实施方案，提供了用于各种有机催化反应的可回收的磁性纳米材料负载的有机催化剂，包括但不限于Paal-Knorr反应，aza-Michael加成和吡唑合成。

公开(公告)号：US20110296746A1

公开(公告)日：2011-12-08

申请号：US13151573

申请日：2011-06-02

申请人： Raúl Hernández Altamirano ,  Luis Silvestre Zamudio Rivera ,  Violeta Yasmín Mena Cervantes ,  Hiram Isaac Beltrán Conde ,  Marco Antonio Domínguez Aguilar ,  Jaquelin Martínez Viramontes ,  Aristeo Estrada Buendía

发明人： Raúl Hernández Altamirano ,  Luis Silvestre Zamudio Rivera ,  Violeta Yasmín Mena Cervantes ,  Hiram Isaac Beltrán Conde ,  Marco Antonio Domínguez Aguilar ,  Jaquelin Martínez Viramontes ,  Aristeo Estrada Buendía

IPC分类号： C10L1/188 ,  C09K15/18 ,  C07C7/20 ,  C23F11/00 ,  C07C229/30

CPC分类号： C07C227/16 ,  C07C227/10 ,  C07C227/26 ,  C07C229/12 ,  C07C229/16 ,  C07C229/24 ,  C09K15/20 ,  C10L1/143 ,  C10L1/1608 ,  C10L1/1616 ,  C10L1/1824 ,  C10L1/1985 ,  C10L1/2222 ,  C10L1/223 ,  C10L10/04 ,  C10L2200/0259 ,  C10L2200/0423 ,  C10L2200/043 ,  C10L2200/0446 ,  C10L2230/14 ,  C10L2270/023 ,  C10L2270/026 ,  C10L2270/04 ,  C10L2270/10 ,  C10L2300/20 ,  C23F11/143

摘要： N-alkyl, N-alkenyl, N-cycloalkyl, N-aryl amino or imino propionic acids with an alkyl chain ranging from 6 to 18 carbons, or alkenyl chain from 8 to 30 carbons, are obtained from a reaction process in the absence of solvent at a temperature range from 30 to 180° C. and a time of 1 to 10 hours at atmospheric pressure. Formulations composed of N-alkyl or N-alkenyl or N-cycloalkyl or N-aryl amino or imino propionic acids, polyethers derived from propylene oxide or ethylene oxide or copolymer thereof and a solvent consisting of aromatic compounds such as toluene or xylene, diesel or gasoline or alcohols such as isopropanol and ethanol, or mixtures thereof, are obtained inhibit ferrous metal corrosion of pipelines and storage tanks and transport crude oil and liquid fuels. A method inhibiting corrosion of ferrous metals adds an effective amount of the corrosion inhibitor to a petroleum based material such as crude oil and liquid fuels such as gasoline, diesel fuel, and aviation fuel.

摘要翻译： 具有6至18个碳原子的烷基链或8至30个碳的链烯基链的N-烷基，N-烯基，N-环烷基，N-芳基氨基或亚氨基丙酸得自不存在 溶剂，在大气压下在30至180℃的温度和1至10小时的时间内进行。 由N-烷基或N-烯基或N-环烷基或N-芳基氨基或亚氨基丙酸组成的制剂，衍生自环氧丙烷或环氧乙烷的聚醚或其共聚物，以及由芳族化合物如甲苯或二甲苯，柴油或 获得汽油或醇，例如异丙醇和乙醇，或其混合物，从而抑制管线和储罐的黑色金属腐蚀并运输原油和液体燃料。 一种抑制黑色金属腐蚀的方法，对石油类材料如汽油，柴油和航空燃料等原油和液体燃料，增加了有效量的缓蚀剂。