-
公开(公告)号：US12258554B2
公开(公告)日：2025-03-25
申请号：US17378845
申请日：2021-07-19
Applicant: BASF SE
Inventor： Isabella Siepe , Heilke Brueser , Kristin Klappach , Karl-Heinrich Schneider , Petra Sproete , Kerstin Hage , Birgit Blanz , Eckhard Thines , Luis Antelo , Louis Pergaud Sandjo , Till Opatz
IPC: C12N1/20 , A01N63/10 , A01N63/25 , C07K14/195
Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to novel fusaricidin-type compounds which are metabolites produced by the strains of the present invention.
-
公开(公告)号：US20220340865A1
公开(公告)日：2022-10-27
申请号：US17620786
申请日：2020-06-29
Applicant: BASF SE
Inventor： Thomas Kaeding , Kerstin Hage , Rodolfo Ham-Zhu
IPC: C12N1/20
Abstract: The present invention is directed to a method of preparing a fermentation medium comprising the steps of a) mixing components of a fermentation medium comprising a complex nutrient source in water, wherein the complex nutrient source is in an amount of 0.5-30% w/v of the fermentation medium; b) adjusting the pH of the fermentation medium obtained in step a) to a pH between pH 3.0 and pH 6.7; c) subjecting the fermentation medium subsequently to a heat treatment and thereafter adjusting the pH to a pH value suitable for cell cultivation. The present invention is further directed to a method a fermentation process comprising cultivation of the cells in the fermentation medium of the invention and the production of a compound of interest. The present invention is further directed to a method for reducing color formation and viscosity during fermentation medium preparation and during the fermentation process.
-
公开(公告)号：US20210355433A1
公开(公告)日：2021-11-18
申请号：US17378845
申请日：2021-07-19
Applicant: BASF SE
Inventor： Isabella Siepe , Heilke Brueser , Kristin Klappach , Karl-Heinrich Schneider , Petra Sproete , Kerstin Hage , Birgit Blanz , Eckhard Thines , Luis Antelo , Louis Pergaud Sandjo , Till Opatz
IPC: C12N1/20 , A01N63/25 , A01N63/10 , C07K14/195
Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to novel fusaricidin-type compounds which are metabolites produced by the strains of the present invention.
-
公开(公告)号：US10548326B2
公开(公告)日：2020-02-04
申请号：US15724894
申请日：2017-10-04
Applicant: BASF SE
Inventor： Isabella Siepe , Heike Brueser , Kristin Klappach , Karl-Heinrich Schneider , Petra Sproete , Kerstin Hage , Birgit Blanz , Eckhard Thines , Luis Antelo , Louis Pergaud Sandjo , Till Opatz
IPC: C07K14/195 , A01N63/02
Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to novel fusaricidin-type compounds which are metabolites produced by the strains of the present invention.
-
Patent Agency Ranking
公开(公告)号：US11788094B2
公开(公告)日：2023-10-17
申请号：US16062291
申请日：2016-12-08
Applicant: BASF SE
Inventor： Max Fabian Felle , Stefan Jenewein , Kerstin Hage , Holger Hartmann
CPC classification number: C12N15/75 , C12N9/0065 , C12N15/63 , C12P1/04 , C12Y111/01006
Abstract: The present invention generally relates to the field of fermentation technology and microorganisms useful for such fermentations. The invention also relates to materials including nucleic acids and proteins useful for altering fermentation characteristics of microorganisms, and to microorganisms comprising such nucleic acids and/or proteins.
-
公开(公告)号：US11064703B2
公开(公告)日：2021-07-20
申请号：US15724866
申请日：2017-10-04
Applicant: BASF SE
Inventor： Isabella Siepe , Heike Brueser , Kristin Klappach , Karl-Heinrich Schneider , Petra Sproete , Kerstin Hage , Birgit Blanz , Eckhard Thines , Luis Antelo , Louis Pergaud Sandjo , Till Opatz
IPC: C07K14/195 , A01N63/10 , C12N1/20
Abstract: The present invention relates to novel isolated bacterial strains, which are members of the genus Paenibacillus, originally isolated from soil and showing antagonistic activity against a broad range of pathogens and being capable of producing antimicrobial metabolites. It was found that the strains Lu16774 and Lu17007 belong to a novel subspecies named Paenibacillus polymyxa ssp. plantarum while the strain Lu17015 belongs to a novel species which is proposed to be Paenibacillus epiphyticus. The present invention also relates to microbial pesticide compositions comprising at least one of such novel bacterial strains, whole culture broth or a cell-free extract or a fraction thereof or at least one metabolite thereof, and/or a mutant of at least one of said novel bacterial strains having all the identifying characteristics of the respective bacterial strain or whole culture broth, cell-free extract, fraction and/or metabolite of the mutant thereof showing antagonistic activity against plant pathogens. The present invention also relates to a method of controlling or suppressing plant pathogens or preventing plant pathogen infections by applying such composition. The present invention also relates to novel fusaricidin-type compounds which are metabolites produced by the strains of the present invention.
-
公开(公告)号：US20240093211A1
公开(公告)日：2024-03-21
申请号：US18463923
申请日：2023-09-08
Applicant: BASF SE
Inventor： Max Fabian Felle , Stefan Jenewein , Kerstin Hage , Holger Hartmann
CPC classification number: C12N15/75 , C12N9/0065 , C12N15/63 , C12P1/04 , C12Y111/01006
Abstract: The present invention generally relates to the field of fermentation technology and microorganisms useful for such fermentations. The invention also relates to materials including nucleic acids and proteins useful for altering fermentation characteristics of microorganisms, and to microorganisms comprising such nucleic acids and/or proteins.
-
公开(公告)号：US20190292514A1
公开(公告)日：2019-09-26
申请号：US16317338
申请日：2017-07-12
Applicant: BASF SE
Inventor： Kerstin Hage , Carsten Schwalb , Gunter Steigelmann , Thomas Kaeding , Sebastian Briechle
Abstract: The present invention is directed to a fermentation medium and a fermentation method using said fermentation medium wherein the fermentation medium comprising a basal medium and a chelating agent having the formula (I) R1—CH(COOX1)—N(CH2COOX1)2, wherein R1 is selected from hydrogen, linear or branched C1-C4-alkyl, phenyl, benzyl, CH2OH, and CH2CH2COOX1, X1 is (MxH1-x), M being a monovalent cation, preferably being selected from ammonium or alkali metal or combinations of at least two of the foregoing, x is in the range of from zero to 1, wherein x is an average value.
-
公开(公告)号：US20190112612A1
公开(公告)日：2019-04-18
申请号：US16062291
申请日：2016-12-08
Applicant: BASF SE
Inventor： Max Fabian Felle , Stefan Jenewein , Kerstin Hage , Holger Hartmann
Abstract: The present invention generally relates to the field of fermentation technology and microorganisms useful for such fermentations. The invention also relates to materials including nucleic acids and proteins useful for altering fermentation characteristics of microorganisms, and to microorganisms comprising such nucleic acids and/or proteins.
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.012 seconds)
