公开(公告)号：US20170283840A1

公开(公告)日：2017-10-05

申请号：US15514321

申请日：2015-09-30

Applicant: BASF SE

Inventor： Michael BRAUN ,  Juergen DAEUWEL ,  Hans-Juergen LANG ,  Peter OEDMAN ,  Kai-Uwe BALDENIUS ,  Matthias KLEINER ,  Michael KIEFER ,  Stephan FREYER ,  Michael BUDDE

IPC: C12P13/02 ,  C09K8/588 ,  C08L33/26 ,  D21H17/37 ,  C07C233/09 ,  C08F20/56

CPC classification number: C12P13/02 ,  C07C233/09 ,  C08F20/56 ,  C08L33/26 ,  C08L2201/54 ,  C09K8/588 ,  C12Y402/01084 ,  D21H17/375

Abstract: The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.

公开(公告)号：US20170247726A1

公开(公告)日：2017-08-31

申请号：US15513670

申请日：2015-09-30

Applicant: BASF SE

Inventor： Michael BUDDE ,  Michael BRAUN ,  Juergen DAEUWEL ,  Peter OEDMAN ,  Kai-Uwe BALDENIUS ,  Matthias KLEINER ,  Stephan FREYER

IPC: C12P13/02 ,  C12N9/78 ,  C12N9/80

CPC classification number: C12P13/02 ,  C12N9/78 ,  C12N9/80 ,  C12Y305/01004 ,  C12Y305/05001

Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.