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    STREPTOMYCES MICROFLAVUS STRAINS AND METHODS OF THEIR USE TO CONTROL PLANT DISEASES AND PESTS
    2.
    发明申请
    STREPTOMYCES MICROFLAVUS STRAINS AND METHODS OF THEIR USE TO CONTROL PLANT DISEASES AND PESTS 审中-公开
    微生物菌株的应用及其使用方法来控制植物病虫害

    公开(公告)号：US20150299754A1

    公开(公告)日：2015-10-22

    申请号：US14688806

    申请日：2015-04-16

    申请人： Bayer CropScience LP

    发明人： Damian CURTIS ,  Shaohua GUAN ,  Magalie GUILHABERT-GOYA ,  Jonathan S. MARGOLIS ,  Reed Nathan ROYALTY ,  Frisby Davis SMITH ,  Colleen TAYLOR ,  Hong ZHU

    IPC分类号： C12P19/40 ,  A01N43/54

    CPC分类号： C12P19/40 ,  A01N43/54 ,  A01N63/02

    摘要： The present invention relates to novel strains of Streptomyces microflavus and methods of their use for controlling diseases or pests of a plant. The invention also relates to a fermentation broth obtained by cultivating a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 2 g/L gougerotin. The invention also relates to a method of producing a fermentation broth of a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 2 g/L gougerotin, the method comprising cultivating the Streptomyces strain in a culture medium containing a digestible carbon source and a digestible nitrogen source under aerobic conditions.

    摘要翻译： 本发明涉及新霉菌Streptomyces microflavus及其用于控制​​植物疾病或害虫的方法。 本发明还涉及通过培养产生Gougerotin的链霉菌属菌株获得的发酵液，其中发酵液含有至少约2g / L gougerotin。 本发明还涉及一种生产发酵链霉菌菌株发酵液的方法，其中发酵液含有至少约2g / L gougerotin，该方法包括在含有可消化碳源的培养基中培养链霉菌属菌株， 在有氧条件下可消化氮源。

    COMPOSITIONS COMPRISING GOUGEROTIN AND A BIOLOGICAL CONTROL AGENT
    5.
    发明申请
    COMPOSITIONS COMPRISING GOUGEROTIN AND A BIOLOGICAL CONTROL AGENT 审中-公开
    包含GOUGEROTIN和生物控制剂的组合物

    公开(公告)号：US20150373973A1

    公开(公告)日：2015-12-31

    申请号：US14766339

    申请日：2014-02-10

    申请人： BAYER CROPSCIENCE LP

    发明人： Wolfram ANDERSCH ,  Reed Nathan ROYALTY ,  Frisby Davis SMITH ,  Bernd SPRINGER ,  Wolfgang THIELERT

    IPC分类号： A01N43/54 ,  A01N63/02 ,  A01N63/00

    CPC分类号： A01N43/54 ,  A01N63/00 ,  A01N63/02 ,  A01N63/04 ,  C12R1/07 ,  C12R1/125 ,  C12R1/465 ,  Y02A50/356

    摘要： The present invention relates to a composition comprising a) isolated gougerotin b) at least one biological control agent selected from specific microorganisms and/or a mutant of it having all identifying characteristics of the respective strain, and/or at least one metabolite produced by the respective strain that exhibits activity against insects, mites, nematodes and/or phytopathogens in a synergistically effective amount. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.

    摘要翻译： 本发明涉及一种组合物，其包含a）分离的gougerotin b）至少一种选自特定微生物的生物控制剂和/或其具有各自菌株的所有鉴定特征的突变体，和/或至少一种由 具有协同有效量的针对昆虫，螨，线虫和/或植物病原体的活性的各自的菌株。 此外，本发明涉及该组合物的用途以及减少植物和植物部分总体损伤的方法。

    STREPTOMYCES MICROFLAVUS STRAINS AND METHODS OF THEIR USE TO CONTROL PLANT DISEASES AND PESTS
    8.
    发明申请
    STREPTOMYCES MICROFLAVUS STRAINS AND METHODS OF THEIR USE TO CONTROL PLANT DISEASES AND PESTS 审中-公开
    微生物菌株的应用及其使用方法来控制植物病虫害

    公开(公告)号：US20140105862A1

    公开(公告)日：2014-04-17

    申请号：US14052094

    申请日：2013-10-11

    申请人： Bayer CropScience LP

    发明人： Brian CAMPBELL ,  Damian CURTIS ,  Shaohua GUAN ,  Magalie GUILHABERT-GOYA ,  Daniel M. JOO ,  Tara LU ,  Jonathan S. MARGOLIS ,  Reed Nathan ROYALTY ,  Gerardo Bueno SALAZAR ,  David SESIN ,  Frisby Davis SMITH ,  Colleen TAYLOR ,  Hong ZHU

    IPC分类号： A01N63/02 ,  A01N43/54

    CPC分类号： A01N63/02 ,  A01N43/54 ,  C12P19/28 ,  C12P19/385

    摘要： The present invention relates to novel strains of Streptomyces microflavus and methods of their use for controlling diseases or pests of a plant. The invention also relates to a fermentation broth obtained by cultivating a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin. The invention also relates to a method of producing a fermentation broth of a gougerotin producing Streptomyces strain, wherein the fermentation broth contains at least about 1 g/L gougerotin, the method comprising cultivating the Streptomyces strain in a culture medium containing a digestible carbon source and a digestible nitrogen source under aerobic conditions, wherein the culture medium contains an amino acid at a concentration effective to achieve a gougerotin concentration of at least 1 g/L. The present disclosure also relates to the molecular cloning of a gougerotin biosynthetic gene cluster from Streptomyces microflavus, and identification of individual genes in the gene cluster as well as the proteins encoded thereby. A gougerotin gene cluster comprising 13 open reading frames (ORFs) is located within a genetic locus of Streptomyces microflavus.

    摘要翻译： 本发明涉及新霉菌Streptomyces microflavus及其用于控制​​植物疾病或害虫的方法。 本发明还涉及通过培养产生Gougerotin的链霉菌菌株而获得的发酵液，其中发酵液含有至少约1g / L gougerotin。 本发明还涉及一种生产发酵木瓜霉菌菌株发酵液的方法，其中发酵液含有至少约1g / L gougerotin，该方法包括在含有可消化碳源的培养基中培养链霉菌属菌株， 在需氧条件下的可消化氮源，其中培养基含有浓度达到至少1g / L的gougerotin浓度的氨基酸。 本公开还涉及从Streptomyces microflavus分子克隆gougerotin生物合成基因簇，以及鉴定基因簇中的各个基因以及由此编码的蛋白质。 包含13个开放阅读框（ORF）的gougerotin基因簇位于Streptomyces microflavus的遗传基因座内。