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公开(公告)号：US11202898B2
公开(公告)日：2021-12-21
申请号：US16600961
申请日：2019-10-14
Applicant: BAYER HEALTHCARE LLC
Inventor： Ralph Schriver , James A. Dedig
Abstract: A bolus control device for use with an injection device, the bolus control device including a valve body having a proximal end opposite a distal end. The valve body defines a fluid channel therethrough to allow a passage of medical fluid from the proximal end to the distal end. A connector is provided at the proximal end and configured for connecting to a fluid inlet line. A connector subassembly is provided at the distal end and configured for connecting to a fluid outlet line. A compressible check valve is disposed within the fluid channel, such that the compressible check valve is adjustable to control a cracking pressure at which the compressible check valve closes.
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公开(公告)号：US09480797B1
公开(公告)日：2016-11-01
申请号：US14925722
申请日：2015-10-28
Applicant: BAYER HEALTHCARE LLC
Inventor： Michael J. Swantner , Richard A. Seman , Barry L. Tucker , Arthur E. Uber, III , Kevin P. Cowan , James A. Dedig , Christopher D. Capone
CPC classification number: A61M5/14566 , A61M5/14546 , A61M5/31515 , A61M2005/14573
Abstract: A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engagable with the piston regardless of a rotational orientation of the piston relative to the plunger.
Abstract translation: 用于注射器的柱塞具有柱塞本体，其具有近端，远端和沿着柱塞纵向轴线在近端和远端之间延伸的周向侧壁。 柱塞还具有至少一个可弹性偏转的保持构件，其具有附接到柱塞本体的第一段和朝向柱塞体的远端突出并相对于第一段可偏转的第二段。 柱塞还具有与至少一个可弹性偏转的保持构件相关联的至少一个致动构件。 所述至少一个致动构件与活塞相互作用，以在所述柱塞相对于所述活塞旋转时偏转所述至少一个可弹性偏转的保持构件。 无论活塞相对于柱塞的旋转取向如何，柱塞可与活塞接合。
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公开(公告)号：US12263136B2
公开(公告)日：2025-04-01
申请号：US17317306
申请日：2021-05-11
Applicant: BAYER HEALTHCARE LLC
Inventor： Kevin Cowan , James A. Dedig , Michael Spohn , Michael McDermott
Abstract: A syringe for delivery of a medical liquid to a container has a body with proximal end, a frustoconical distal end, and a cylindrical sidewall extending between the proximal end and the distal end along a longitudinal axis. The syringe includes a nozzle at a distal portion of the frustoconical distal end of the syringe, the nozzle having a throughbore providing fluid communication between an interior volume of the syringe and a medical connector configured to be connected to the nozzle. The nozzle includes a plurality of longitudinal ribs formed on an inner surface of the nozzle. The syringe is designed so that the plurality of longitudinal ribs directs a flow of a medical fluid along an inner surface of the frustoconical distal end and along an interior surface of the cylindrical sidewall of the syringe under a Coandǎ effect. Syringe and connector assemblies and methods for reducing a number of bubbles formed in a medical fluid during a syringe filling procedure are also described.
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公开(公告)号：US11007118B2
公开(公告)日：2021-05-18
申请号：US15778350
申请日：2016-11-23
Applicant: BAYER HEALTHCARE LLC
Inventor： Kevin Cowan , James A. Dedig , Michael Spohn , Michael McDermott , Matthew McGee
Abstract: A fill adapter for delivery of a medical liquid to a container has a body with a distal end, a proximal end, and a central bore extending between the distal end and the proximal end along a longitudinal axis. The central bore has an angled portion at the proximal end of the body such that a diameter of the central portion increases at the angled portion in a direction from the distal end to the proximal end. The fill adapter further has a flow controller disposed within the central bore at a distal end of the angled portion such that a gap is formed between an outer surface of the flow controller and an inner surface of the central bore. The flow controller is shaped to direct liquid flowing through the central bore to flow through the gap and along the angled portion of the central bore under a Coandă effect.
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公开(公告)号：US10029220B2
公开(公告)日：2018-07-24
申请号：US15417945
申请日：2017-01-27
Applicant: BAYER HEALTHCARE LLC
Inventor： Ralph H. Schriver , Andreas Maihoefer , James A. Dedig , Michael A. Spohn , Herbert M. Grubic , Michael J. Swantner , Adam Caruso
Abstract: A fluid path set includes a first fluid line having a proximal end fluidly connectable to a source of a first fluid and a second fluid line having a proximal end fluidly connectable to a source of a second fluid. A flow mixing device is in fluid communication with distal ends of the first and second fluid lines. The flow mixing device includes a housing, a first fluid port provided for receiving the first fluid, and a second fluid port for receiving the second fluid. A mixing chamber is disposed within the housing and is in fluid communication with the first and second fluid ports. A third fluid port in fluid communication with the mixing chamber for discharging a mixed solution of the first and second fluids. A turbulent flow inducing member is disposed within the mixing chamber for promoting turbulent mixing of the first and second fluids.
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Patent Agency Ranking
公开(公告)号：US11291766B2
公开(公告)日：2022-04-05
申请号：US15769550
申请日：2016-10-28
Applicant: BAYER HEALTHCARE LLC
Inventor： Michael J. Swantner , Richard A. Seman , Barry L. Tucker , Arthur E. Uber, III , Kevin P. Cowan , James A. Dedig , Christopher D. Capone
Abstract: A pressure jacket for use with a fluid injector may have a pressure jacket body having a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a pressure jacket longitudinal axis. The pressure jacket may further have at least one resiliently deflectable retaining member having a first segment attached to the pressure jacket body and a second segment protruding from the first segment toward the distal end of the pressure jacket body and deflectable relative to the first segment. The pressure jacket may further have at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member may interact with a housing of the fluid injector when the pressure jacket is connected to the housing to deflect the at least one resiliently deflectable retaining member upon rotation of the pressure jacket.
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公开(公告)号：US10857345B2
公开(公告)日：2020-12-08
申请号：US15974764
申请日：2018-05-09
Applicant: BAYER HEALTHCARE LLC
Inventor： Arthur E. Uber, III , Kevin Cowan , James A. Dedig , David M. Griffiths , Edward J. Rhinehart , Benjamin Taggart , Mark Trocki
Abstract: A medical connector assembly for establishing a fluid connection between a first medical device and a second medical device includes a multi-use connector and a plurality of single-use connectors connected in series. The multi-use connector has a proximal end opposite a distal end along a longitudinal length thereof. The plurality of single-use connectors each have a proximal end opposite a distal end along a longitudinal length thereof. The distal end of the multi-use connector is releasably connected to the proximal end of a first of the serially-connected single-use connectors. When a second of the serially-connected single-use connectors is disconnected from the first single-use connector, the first single-use connector remains connected to the multi-use medical connector as a sterility retaining cover.
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公开(公告)号：US10512721B2
公开(公告)日：2019-12-24
申请号：US15334644
申请日：2016-10-26
Applicant: BAYER HEALTHCARE LLC
Inventor： Michael J. Swantner , Richard A. Seman , Barry L. Tucker , Arthur E. Uber, III , Kevin P. Cowan , James A. Dedig , Christopher D. Capone , Jaroslaw Wlodarczyk
Abstract: A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engagable with the piston regardless of a rotational orientation of the piston relative to the plunger.
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公开(公告)号：US11278853B2
公开(公告)日：2022-03-22
申请号：US16013050
申请日：2018-06-20
Applicant: BAYER HEALTHCARE LLC
Inventor： Ralph H. Schriver , Andreas Maihoefer , James A. Dedig , Michael A. Spohn , Herbert M. Grubic , Michael J. Swantner , Adam Caruso
IPC: G01F11/02 , B01F5/06 , A61M5/00 , A61M5/168 , A61M39/10 , B01F5/02 , B01F7/00 , B01F13/00 , B01F3/08 , B01F5/00 , B01F15/00 , A61M39/00
Abstract: A method for controlling fluid ratio accuracy during a dual flow injection with a powered injection system is described. The method includes predicting a first capacitance volume of a first syringe comprising a first medical fluid and a second capacitance volume of a second syringe comprising a second medical fluid with a first capacitance correction factor and a second capacitance correction factor, respectively, selecting a ratio of the first medical fluid and the second medical fluid to be administered to a patient in the dual flow injection, determining a relative acceleration ratio of a first piston of the first syringe and a second piston of a second syringe based on the predicted first capacitance volume and the predicted second capacitance volume, wherein the relative acceleration ratio is selected to maintain the selected ratio of the first medical fluid and the second medical fluid during the dual flow injection, and injecting a mixture of a first medical fluid and a second medical fluid having the selected ratio with the powered injection system.
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公开(公告)号：US10589018B2
公开(公告)日：2020-03-17
申请号：US15119467
申请日：2015-02-18
Applicant: Bayer HealthCare LLC
Inventor： Arthur E. Uber, III , Ralph H. Schriver , Barry L. Tucker , James A. Dedig
Abstract: A multi-dose disposable fluid delivery system includes at least one fluid container, a multi-use fluid path set, and a plurality of single-use fluid path sets. The at least one fluid container has a connection port configured for fluidly connecting with a first end of the multi-use fluid path set. The second end of the multi-fluid path set is configured for fluidly connecting to a fluid injection apparatus. The plurality of single-use fluid path sets is connected in sequence to define a fluid path extending from a first single-use fluid path set to a last single- use fluid path set. Each of the plurality single-use fluid path sets has a first end and a second end. The first end of the first single-use fluid path set is configured for connecting to a delivery line. The second end of the last single-use fluid path set is configured for connecting to the injection apparatus.
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