公开(公告)号：US20140293734A1

公开(公告)日：2014-10-02

申请号：US14278527

申请日：2014-05-15

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Jörg KAULING ,  Helmut BROD ,  Sebastian SCHMIDT ,  Martin POGGEL ,  Björn FRAHM ,  Reinhold ROSE

IPC: B01J19/28 ,  B01F11/00

CPC classification number: B01J19/28 ,  B01F3/04269 ,  B01F11/0002 ,  B01F11/0008 ,  B01F13/0018 ,  B01F13/0032 ,  B01F15/00733 ,  B01F15/0085 ,  B01F15/00915 ,  B01F15/065 ,  B01F15/066 ,  B01F2003/04361 ,  B01J19/123 ,  B01J19/285 ,  B01J2219/0025 ,  B01J2219/00761 ,  B01J2219/185 ,  B01J2219/192 ,  C12M23/14 ,  C12M23/28 ,  C12M27/02 ,  C12M27/10

Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.

Abstract translation: 本发明涉及一种围绕其固定的，优选垂直的轴以振荡旋转方式驱动的反应器，优选用于生物技术和制药应用。 通过其混合，悬浮，气态物质运输，传热，照射和颗粒保留的工艺增强性能，确保了工业规模的适用性。 没有轴封成功的反应器相对于无菌技术可以特别稳定的生产，避免了当反应器被构造为一次性反应器时所需的清洁和清洁验证。

公开(公告)号：US20140373328A1

公开(公告)日：2014-12-25

申请号：US14337737

申请日：2014-07-22

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Martin POGGEL ,  Jörg KAULING ,  Sebastian SCHMIDT ,  Erhard BECKERS

IPC: B23P19/02 ,  F16L11/118 ,  F16L11/20

CPC classification number: B23P19/02 ,  B01J19/123 ,  B01J19/242 ,  B01J2219/0002 ,  B29C65/66 ,  B29C66/1122 ,  B29C66/52272 ,  B29C66/53241 ,  B29C66/71 ,  B29C66/7465 ,  B29L2023/18 ,  C02F1/325 ,  C02F2201/004 ,  F16L11/118 ,  F16L11/1185 ,  F16L11/20 ,  Y10T29/49867 ,  Y10T29/49869 ,  Y10T29/4987 ,  Y10T29/49945 ,  Y10T29/53987 ,  B29K2027/18

Abstract: Device for mounting flexible, profiled hollow cylinders onto cylindrical elements. Profiled hollow cylinders which are mounted onto a cylindrical element form excellent modules for irradiating fluid media with electromagnetic radiation.

Abstract translation: 用于将柔性，异型空心圆柱体安装到圆柱形元件上的装置。 安装在圆柱形元件上的异型空心圆筒形成用于用电磁辐射照射流体介质的优良模块。

公开(公告)号：US20140080213A1

公开(公告)日：2014-03-20

申请号：US14047531

申请日：2013-10-07

Applicant: BAYER INTELLECTUAL PROPERTY GMBH

Inventor： Jörg KAULING ,  Helmut BROD ,  Sebastian SCHMIDT ,  Martin POGGEL ,  Björn FRAHM ,  Reinhold ROSE

IPC: C12M1/00

CPC classification number: B01J19/28 ,  B01F3/04269 ,  B01F11/0002 ,  B01F11/0008 ,  B01F13/0018 ,  B01F13/0032 ,  B01F15/00733 ,  B01F15/0085 ,  B01F15/00915 ,  B01F15/065 ,  B01F15/066 ,  B01F2003/04361 ,  B01J19/123 ,  B01J19/285 ,  B01J2219/0025 ,  B01J2219/00761 ,  B01J2219/185 ,  B01J2219/192 ,  C12M23/14 ,  C12M23/28 ,  C12M27/02 ,  C12M27/10

Abstract: The invention relates to a reactor driven in an oscillatory-rotary manner about its fixed, preferably vertical, axis, for preferably biotechnological and pharmaceutical applications. By means of its process-intensifying properties for mixing, suspension, gaseous material transport, heat transfer, irradiation and particle retention, the applicability on the industrial scale is ensured. The reactor which succeeds without a shaft seal permits particularly robust production with respect to sterile technique with avoidance of cleaning and cleaning validation required when the reactor is constructed as a single-use reactor.