-
公开(公告)号：US20150045344A1
公开(公告)日：2015-02-12
申请号：US14522510
申请日：2014-10-23
发明人： Franz VON NUSSBAUM , Dagmar KARTHAUS , Sonja ANLAUF , Martina DELBECK , Volkhart Min-Jian LI , Daniel MEIBOM , Klemens LUSTIG , Jens SCHAMBERGER
IPC分类号： C07D487/04 , A61K31/513 , A61K45/06 , C07D409/12 , C07D403/06 , C07D413/12 , A61K31/519 , A61K31/541 , C07D401/14 , C07D413/06 , A61K31/5377 , C07D403/12 , C07D239/22 , C07D401/06
CPC分类号： C07D487/04 , A61K31/513 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K45/06 , C07D239/22 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/12
摘要： The present invention relates to novel 4-(4-cyano-2-thioaryl)dihydropyrimidin-2-one derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
摘要翻译： 本发明涉及新的4-（4-氰基-2-硫代芳基）二氢嘧啶-2-酮衍生物，其制备方法，单独使用或组合用于治疗和/或预防疾病，以及它们 用于制备治疗和/或预防疾病的药物，特别是用于治疗和/或预防肺和心血管系统疾病。
-
公开(公告)号：US20140309307A1
公开(公告)日：2014-10-16
申请号：US14304171
申请日：2014-06-13
发明人： Michael HAHN , Thomas LAMPE , Johannes-Peter STASCH , Karl-Heinz SCHLEMMER , Frank WUNDER , Volkhart Min-Jian LI , Eva-Maria BECKER , Friederike STOLL , Andreas KNORR , Elisabeth WOLTERING
IPC分类号： C07C233/55 , A61K45/06 , A61K31/196
CPC分类号： C07C231/14 , A61K9/0053 , A61K31/196 , A61K45/06 , C07C233/55 , C07C235/38 , C07C2601/02 , C07C2601/04 , C07C2601/08
摘要： The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
摘要翻译： 本申请涉及在3-位上带有支链或环状烷基取代基的新型3-苯基丙酸衍生物，其制备方法，其用于治疗和/或预防疾病及其用于制备药物的用途 用于治疗和/或预防疾病，特别是用于治疗和/或预防心血管疾病。
-
3.发明申请TRIAZOLO AND TETRAZOLO PYRIMIDINE DERIVATIVES AS HNE INHIBITORS FOR TREATING COPD 有权三唑和四氮唑吡啶衍生物作为治疗COPD的HNE抑制剂公开(公告)号：US20140038988A1
公开(公告)日：2014-02-06
申请号：US14047458
申请日：2013-10-07
发明人： Franz VON NUSSBAUM , Dagmar KARTHAUS , SONJA ANLAUF , Martina DELBECK , Volkhart Min-Jian LI , Daniel MEIBOM , Klemens LUSTIG
IPC分类号： C07D487/04 , A61K45/06 , C07D487/14 , A61K31/519
CPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , C07D487/14
摘要： The present invention relates to novel heterocyclically fused diaryldihydropyrimidine derivatives, to processes for their preparation, to their use alone or in combination for the treatment and/or prevention of diseases and also to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of disorders of the lung and the cardiovascular system.
摘要翻译： 本发明涉及新颖的杂环稠合二芳基二氢嘧啶衍生物，其制备方法，单独使用或组合用于治疗和/或预防疾病的用途，以及其用于制备用于治疗和/或预防疾病的药物的用途 ，特别是用于治疗和/或预防肺和心血管系统疾病。
-
4.发明申请BENZIMIDAZOLE AND PYRAZOLOPYRIDINE DERIVATIVES FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASES 审中-公开用于治疗和/或预防心脏血管疾病的苯唑咪唑和吡唑并吡啶衍生物公开(公告)号：US20130303559A1
公开(公告)日：2013-11-14
申请号：US13941967
申请日：2013-07-15
发明人： Alexander STRAUB , Frank SÜßMEIER , Frank WUNDER , Johannes-Peter STASCH , Volkhart Min-Jian LI , Joachim MITTENDORF
IPC分类号： C07D403/04 , A61K31/506 , A61K45/06 , C07D471/04
CPC分类号： C07D403/04 , A61K31/506 , A61K45/06 , C07D403/14 , C07D471/04
摘要： The present application relates to novel fused, heteroatom-bridged pyrazole and imidazole derivatives, to processes for their preparation, to their use, alone or in combination, for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
摘要翻译： 本申请涉及新的稠合，杂原子桥连的吡唑和咪唑衍生物，其制备方法，单独或组合用于治疗和/或预防疾病及其用于制备用于治疗的药物的用途 和/或预防疾病，特别是用于治疗和/或预防心血管疾病。
-
公开(公告)号：US20130237551A1
公开(公告)日：2013-09-12
申请号：US13851373
申请日：2013-03-27
发明人： Markus FOLLMANN , Johannes-Peter STASCH , Gorden REDLICH , Jens ACKERSTAFF , Nils GRIEBENOW , Walter KROH , Andreas KNORR , Eva-Maria BECKER , Frank WUNDER , Volkhart Min-Jian LI , Elke HARTMANN , Joachim MITTENDORF , Karl-Heinz SCHLEMMER , Rolf JAUTELAT , Donald BIERER
IPC分类号： A61K31/506 , A61K45/06
CPC分类号： A61K31/506 , A61K45/06 , C07C57/145 , C07C309/04 , C07C309/05 , C07D471/04
摘要： The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
-
公开(公告)号：US20150080414A1
公开(公告)日：2015-03-19
申请号：US14552122
申请日：2014-11-24
发明人： Markus FOLLMANN , Johannes-Peter STASCH , Gorden REDLICH , Jens ACKERSTAFF , Nils GRIEBENOW , Walter KROH , Andreas KNORR , Eva-Maria BECKER , Frank WUNDER , Volkhart Min-Jian LI , Elke HARTMANN , Joachim MITTENDORF , Karl-Heinz SCHLEMMER , Rolf JAUTELAT , Donald BIERER
IPC分类号： C07D471/04 , A61K45/06 , A61K31/506
CPC分类号： A61K31/506 , A61K45/06 , C07C57/145 , C07C309/04 , C07C309/05 , C07D471/04
摘要： The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
摘要翻译： 本申请涉及新的取代的5-氟-1H-吡唑并吡啶，其制备方法，单独使用或组合用于治疗和/或预防疾病，以及它们用于制备用于治疗和/ 或预防疾病，特别是用于治疗和/或预防心血管疾病。
-
公开(公告)号：US20140142069A1
公开(公告)日：2014-05-22
申请号：US14045630
申请日：2013-10-03
发明人： Thomas LAMPE , Michael HAHN , Johannes-Peter STASCH , Karl-Heinz SCHLEMMER , Frank WUNDER , Sherif EL SHEIKH , Volkhart Min-Jian LI , Eva-Maria BECKER-PELSTER , Friederike STOLL , Andreas KNORR
IPC分类号： C07C233/88 , A61K31/655 , C07C231/02 , A61K31/196
CPC分类号： C07C233/88 , A61K31/196 , A61K31/655 , C07C205/38 , C07C231/02 , C07C233/45 , C07C233/55 , C07C255/60 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07D305/06
摘要： The present application relates to novel 3-phenylpropionic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
摘要翻译： 本申请涉及新的3-苯基丙酸衍生物，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病的药物的用途，特别是 治疗和/或预防心血管疾病。
-
公开(公告)号：US20190185415A1
公开(公告)日：2019-06-20
申请号：US16230957
申请日：2018-12-21
发明人： Michael HAHN , Thomas LAMPE , Johannes-Peter STASCH , Karl-Heinz SCHLEMMER , Frank WUNDER , Volkhart Min-Jian LI , Eva-Maria BECKER-PELSTER , Friederike STOLL , Andreas KNORR , Elisabeth WOLTERING
IPC分类号： C07C231/14 , A61K9/00 , A61K45/06 , C07C233/55 , A61K31/196 , C07C235/38
CPC分类号： C07C231/14 , A61K9/0053 , A61K31/196 , A61K45/06 , C07C233/55 , C07C235/38 , C07C2601/02 , C07C2601/04 , C07C2601/08
摘要： The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
-
公开(公告)号：US20180282262A1
公开(公告)日：2018-10-04
申请号：US16001146
申请日：2018-06-06
发明人： Michael HAHN , Thomas LAMPE , Johannes-Peter STASCH , Karl-Heinz SCHLEMMER , Frank WUNDER , Volkhart Min-Jian LI , Eva-Maria BECKER-PELSTER , Friederike STOLL , Andreas KNORR , Elisabeth WOLTERING
IPC分类号： C07C231/14 , A61K31/196 , C07C235/38 , C07C233/55 , A61K45/06 , A61K9/00
CPC分类号： C07C231/14 , A61K9/0053 , A61K31/196 , A61K45/06 , C07C233/55 , C07C235/38 , C07C2601/02 , C07C2601/04 , C07C2601/08
摘要： The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
-
公开(公告)号：US20160264515A1
公开(公告)日：2016-09-15
申请号：US15158331
申请日：2016-05-18
发明人： Michael HAHN , Thomas LAMPE , Johannes-Peter STASCH , Karl-Heinz SCHLEMMER , Frank WUNDER , Volkhart Min-Jian LI , Eva-Maria BECKER , Friederike STOLL , Andreas KNORR , Elisabeth WOLTERING
IPC分类号： C07C231/14 , A61K45/06 , A61K9/00 , A61K31/196
CPC分类号： C07C231/14 , A61K9/0053 , A61K31/196 , A61K45/06 , C07C233/55 , C07C235/38 , C07C2601/02 , C07C2601/04 , C07C2601/08
摘要： The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.02 秒)
