公开(公告)号：US20170227528A1

公开(公告)日：2017-08-10

申请号：US15515501

申请日：2014-09-30

申请人： BGI SHENZHEN CO., LIMITED ,  BGI SHENZHEN

发明人： Qiang Feng ,  Zhipeng Liu ,  Nan Meng ,  Jun Wang

IPC分类号： G01N33/50 ,  G01N30/72

CPC分类号： G01N33/5091 ,  G01N30/02 ,  G01N30/62 ,  G01N30/72 ,  G01N33/48 ,  G01N2030/027 ,  G01N2800/324

摘要： The present invention relates to a disease-specific metabolite profile, and particularly to a biomarker composition obtained by screening from blood plasma-specific profiles of coronary heart disease subjects. The present invention also relates to a use of the biomarker compositions in risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease, and to a method for risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease. The biomarker composition as provided by the present invention can be used for early diagnosis of coronary heart disease and has high sensitivity, good specificity and good application prospects.

公开(公告)号：US20170234852A1

公开(公告)日：2017-08-17

申请号：US15515513

申请日：2014-09-30

申请人： BGI SHENZHEN CO., LIMITED ,  BGI SHENZHEN

发明人： Qiang Feng ,  Zhipeng Liu ,  Nan Meng ,  Jun Wang

IPC分类号： G01N33/493 ,  G06F19/24 ,  G01N30/72

CPC分类号： G01N33/493 ,  G01N30/02 ,  G01N30/62 ,  G01N30/7233 ,  G01N33/48 ,  G01N33/6893 ,  G01N2570/00 ,  G01N2800/324 ,  G01N2800/50 ,  G01N2800/56 ,  G06F19/324 ,  G16B40/00 ,  G16H50/30

摘要： The present invention relates to a disease-specific metabolite profile, and particularly to a biomarker composition obtained by screening from urine-specific metabolite profiles of coronary heart disease subjects. The present invention also relates to a use of the biomarker compositions in risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease, and to a method for risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease. The biomarker composition as provided by the present invention can be used for early diagnosis of coronary heart disease and has high sensitivity, good specificity and good application prospects.

公开(公告)号：US20150037286A1

公开(公告)日：2015-02-05

申请号：US14516373

申请日：2014-10-16

申请人： BGI Shenzhen Co., Limited

发明人： Junjie Qin ,  Shenghui Li ,  Jianfeng Zhu ,  Xiaoping Li ,  Suisha Liang ,  Jun Wang ,  Jian Wang ,  Huanming Yang ,  Qiang Feng

IPC分类号： A61K35/74 ,  A23L1/30

CPC分类号： A61K35/74 ,  A23L33/135 ,  A23V2002/00 ,  A61K9/19 ,  C12N1/20 ,  Y02A50/481

摘要： The present invention provides use of Roseburia in the preparation of composition for prevention and/or treatment of obesity related diseases. Also provided are a composition used in the treatment and prevention for obesity related diseases, comprising pharmaceutical, drink, food, and/or animal feed composition, etc; and a method of reducing body weight and/or blood glucose.

摘要翻译： 本发明提供玫瑰红利用于预防和/或治疗肥胖相关疾病的组合物的制备中的用途。 还提供了用于治疗和预防肥胖相关疾病的组合物，包括药物，饮料，食物和/或动物饲料组合物等; 以及降低体重和/或血糖的方法。

公开(公告)号：US10526659B2

公开(公告)日：2020-01-07

申请号：US15017087

申请日：2016-02-05

申请人： BGI Shenzhen Co., Limited ,  BGI Shenzhen

发明人： Qiang Feng ,  Dongya Zhang ,  Longqing Tang ,  Jun Wang

IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12Q1/6886 ,  C12Q1/6806

摘要： Biomarkers and methods related to microbiota for predicting the risk of a disease, particularly colorectal cancer (CRC), are described.

公开(公告)号：US10100360B2

公开(公告)日：2018-10-16

申请号：US14418800

申请日：2013-06-05

申请人： BGI SHENZHEN ,  BGI SHENZHEN CO., LIMITED

发明人： Shenghui Li ,  Qiang Feng ,  Zhuye Jie ,  Dongya Zhang ,  Junjie Qin ,  Jun Wang ,  Jian Wang ,  Huanming Yang

IPC分类号： C12Q1/68 ,  G06F19/22 ,  G16H50/20 ,  C12Q1/6883

摘要： Biomarkers for diabetes and usages thereof are provided. And the biomarkers are nucleotides having polynucleotide sequences defined in SEQ ID NOs: 1-50.

公开(公告)号：US20150292011A1

公开(公告)日：2015-10-15

申请号：US14418800

申请日：2013-06-05

申请人： BGI Shenzhen Co., Limited ,  BGI SHENZHEN

发明人： Shenghui Li ,  Qiang Feng ,  Zhuye Jie ,  Dongya Zhang ,  Junjie Qin ,  Jun Wang ,  Jian Wang ,  Huanming Yang

IPC分类号： C12Q1/68 ,  G06F19/00 ,  G06F19/22

CPC分类号： C12Q1/6883 ,  C12Q2600/112 ,  C12Q2600/156 ,  C12Q2600/158 ,  G06F19/22 ,  G16H50/20

摘要： Biomarkers for diabetes and usages thereof are provided. And the biomarkers are nucleotides having polynucleotide sequences defined in SEQ ID NOs: 1-50.

摘要翻译： 提供糖尿病生物标记物及其用途。 并且生物标志物是具有SEQ ID NO：1-50中定义的多核苷酸序列的核苷酸。