公开(公告)号：US20140018911A1

公开(公告)日：2014-01-16

申请号：US13939534

申请日：2013-07-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pu Zhou ,  Huisun Wang ,  James Q. Feng

IPC: A61F2/24

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2210/0004 ,  A61F2220/0075

Abstract: A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.

Abstract translation: 心脏瓣膜输送系统包括具有外护套的低轮廓导管，外护套在其中具有支架和置换心脏瓣膜。 在失业的配置中，支架位于替换心脏瓣膜的远端。 然而，部署后，支架和置换心脏瓣膜扩张，置换心脏瓣膜位于支架内。

公开(公告)号：US10729893B2

公开(公告)日：2020-08-04

申请号：US16033458

申请日：2018-07-12

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Chris Manderfeld ,  James Q. Feng

IPC: A61M25/10 ,  A61B17/3207 ,  A61M25/00 ,  A61B17/22 ,  B29C65/48

Abstract: A medical balloon catheter including a catheter shaft and an inflatable balloon secured to a distal portion of the catheter shaft. One or more cutting blades are secured to the inflatable balloon by a first polymeric adhesive material forming a mounting pad encasing a base portion of the cutting blade therein, and a second polymeric adhesive material adhesively bonding the mounting pad to a surface of the balloon. The first polymeric adhesive material has a first ductility and the second polymeric adhesive material has a second ductility greater than the first ductility.

公开(公告)号：US10046146B2

公开(公告)日：2018-08-14

申请号：US15056304

申请日：2016-02-29

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Chris Manderfeld ,  James Q. Feng

IPC: B29C65/48 ,  A61M25/10 ,  A61B17/3207 ,  A61M25/00 ,  A61B17/22

Abstract: A medical balloon catheter including a catheter shaft and an inflatable balloon secured to a distal portion of the catheter shaft. One or more cutting blades are secured to the inflatable balloon by a first polymeric adhesive material forming a mounting pad encasing a base portion of the cutting blade therein, and a second polymeric adhesive material adhesively bonding the mounting pad to a surface of the balloon. The first polymeric adhesive material has a first ductility and the second polymeric adhesive material has a second ductility greater than the first ductility.

公开(公告)号：US09889007B2

公开(公告)日：2018-02-13

申请号：US14997686

申请日：2016-01-18

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Pu Zhou ,  Huisun Wang ,  James Q. Feng

IPC: A61F2/24 ,  A61F2/966

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2210/0004 ,  A61F2220/0075

Abstract: A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.

公开(公告)号：US20160128831A1

公开(公告)日：2016-05-12

申请号：US14997686

申请日：2016-01-18

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Pu Zhou ,  Huisun Wang ,  James Q. Feng

IPC: A61F2/24 ,  A61F2/966

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2210/0004 ,  A61F2220/0075

Abstract: A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.

Abstract translation: 心脏瓣膜输送系统包括具有外护套的低轮廓导管，外护套在其中具有支架和置换心脏瓣膜。 在失业的配置中，支架位于替换心脏瓣膜的远端。 然而，部署后，支架和置换心脏瓣膜扩张，置换心脏瓣膜位于支架内。

公开(公告)号：US20150250772A1

公开(公告)日：2015-09-10

申请号：US14719599

申请日：2015-05-22

Applicant: Boston Scientific Scimed, Inc.

Inventor： Steven L. Kangas ,  James Q. Feng ,  Hongxia Zeng ,  Yen-Lane Chen

IPC: A61K31/436 ,  A61L27/54 ,  A61L29/08 ,  A61L27/28

CPC classification number: A61K31/436 ,  A61F2/00 ,  A61F2/02 ,  A61K31/337 ,  A61L27/28 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/20 ,  A61L2300/416 ,  A61L2300/63 ,  C09D5/16

Abstract: A medical device having a polymer-free outer surface layer comprising a crystalline drug selected from the group consisting of everolimus, tacrolimus, sirolimus, zotarolimus, biolimus, and rapamycin. The device may be produced by a method comprising the steps of providing a medical device; applying a solution of the drug to said portion of the outer surface to form a coating of amorphous drug; and vapor annealing the drug with a solvent vapor to form crystalline drug; wherein a seed layer of a crystalline form of said drug having a maximum particle size of about 10 μm or less is applied to at least said portion of the outer surface of the device before or after applying the drug solution, but before vapor annealing the amorphous coating.

Abstract translation: 一种具有无聚合物外表面层的医疗装置，其包含选自依维莫司，他克莫司，西罗莫司，佐他莫司，生物利莫霉素和雷帕霉素的结晶药物。 该装置可以通过包括以下步骤的方法制造：提供医疗装置; 将所述药物的溶液施加到所述外表面的所述部分以形成无定形药物的包衣; 并用溶剂蒸气对药物进行蒸汽退火以形成结晶药物; 其中在施加药物溶液之前或之后，在装置的外表面的至少所述部分上施加具有最大粒径为约10μm以下的所述药物的结晶形式的晶种层，但是在汽化退火之前 涂层。

公开(公告)号：US09259315B2

公开(公告)日：2016-02-16

申请号：US13939534

申请日：2013-07-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： Pu Zhou ,  Huisun Wang ,  James Q. Feng

IPC: A61F2/24 ,  A61F2/966

CPC classification number: A61F2/2436 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2/966 ,  A61F2210/0004 ,  A61F2220/0075

Abstract: A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.

Abstract translation: 心脏瓣膜输送系统包括具有外护套的低轮廓导管，外护套在其中具有支架和置换心脏瓣膜。 在失业的配置中，支架位于替换心脏瓣膜的远端。 然而，部署后，支架和置换心脏瓣膜扩张，置换心脏瓣膜位于支架内。

公开(公告)号：US20140025085A1

公开(公告)日：2014-01-23

申请号：US13893399

申请日：2013-05-14

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： Pu Zhou ,  Huisun Wang ,  James Q. Feng ,  Dongming Hou

IPC: A61M25/10 ,  A61B17/12 ,  A61B17/42

CPC classification number: A61M25/1002 ,  A61B17/12109 ,  A61B17/12159 ,  A61B17/42 ,  A61B2017/00845 ,  A61B2017/00867 ,  A61B2017/1205 ,  A61B2017/4216 ,  A61M25/0023 ,  A61M25/1029 ,  A61M31/007 ,  A61M2025/0024 ,  A61M2025/0042

Abstract: A catheter is disclosed, which is capable of delivering embolization beads for treating uterine fibroids. The elongate catheter shaft includes a radially expandable portion at its distal end, which can expand radially locally when an embolization bead passes through it. In some cases, the catheter shaft includes a non-expandable portion, with an inner diameter comparable to the bead diameter, between the handle and the radially expandable portion. In some cases, the radially expandable portion is made from a tubular braid, stretched longitudinally over a mandrel, and encased in a lubricious soft polymer while still stretched. In other cases, the radially expandable portion is made from a slotted nitinol tube, encased in a lubricious soft polymer below the nitinol transition temperature. The polymer is thick enough to prevent the encased element from returning to its unstretched diameter or a larger size above the transition temperature.

Abstract translation: 公开了一种导管，其能够递送用于治疗子宫肌瘤的栓塞珠。 细长的导管轴在其远端包括径向可膨胀的部分，当栓塞珠通过它时，其可以径向局部膨胀。 在一些情况下，导管轴包括在手柄和径向可扩张部分之间具有与胎圈直径相当的内径的不可扩张部分。 在一些情况下，径向可膨胀部分由管状编织物制成，在心轴上纵向延伸，并且在仍然被拉伸的情况下被包裹在光滑的软质聚合物中。 在其他情况下，径向可膨胀部分由开槽的镍钛诺管制成，封装在低于镍钛诺转变温度的润滑软聚合物中。 聚合物足够厚以防止被包裹的元件返回到其未拉伸直径或超过转变温度的较大尺寸。