公开(公告)号：US10751432B2

公开(公告)日：2020-08-25

申请号：US16334884

申请日：2017-09-20

申请人： BRACCO DIAGNOSTICS INC.

发明人： Andrew Schimmoeller ,  Clif Moyers ,  Adrian Nunn ,  Brian Cherundolo ,  Joseph Dennis

IPC分类号： A61K51/12 ,  G21G1/00 ,  G21F5/015 ,  G21G4/08 ,  A61M5/00 ,  A61M5/14 ,  A61M5/162 ,  A61M5/168 ,  G01T1/20 ,  G21H5/02 ,  A61B5/055 ,  A61B6/03

摘要： A shielding assembly may be used in a nuclear medicine infusion system that generates and infuse radioactive liquid into a patient undergoing a diagnostic imaging procedure. In some examples, the shielding assembly has multiple compartments each formed of a shielding material providing a barrier to radioactive radiation. For example, the shielding assembly may have a first compartment configured to receive a radioisotope generator that generates a radioactive eluate via elution, a second compartment configured to receive a beta detector, and a third compartment configured to receive a gamma detector. In some examples, the compartments are arranged to minimize background radiation emitted by the radioisotope generator and detected by the gamma detector to enhance the quality of the measurements made by the gamma detector.

公开(公告)号：US11752254B2

公开(公告)日：2023-09-12

申请号：US16334882

申请日：2017-09-20

申请人： BRACCO DIAGNOSTICS INC.

发明人： Clif Moyers ,  Adrian Nunn ,  Andrew Schimmoeller ,  Brian Cherundolo

IPC分类号： A61M5/00 ,  G21G4/08 ,  A61N5/10 ,  A61M5/142 ,  G01T1/16 ,  A61K51/12 ,  G21F5/015 ,  G21G1/00 ,  A61M5/14 ,  A61M5/162 ,  A61M5/168 ,  G01T1/20 ,  G21H5/02 ,  G01T7/00

CPC分类号： A61M5/007 ,  A61K51/121 ,  A61K51/1282 ,  A61M5/142 ,  A61M5/1408 ,  A61M5/162 ,  A61M5/16827 ,  A61M5/16881 ,  A61N5/1007 ,  G01T1/20 ,  G01T7/005 ,  G21F5/015 ,  G21G1/0005 ,  G21G4/08 ,  G21H5/02 ,  A61K2123/00 ,  A61M2205/18 ,  A61M2205/3313 ,  A61M2205/3389 ,  A61M2205/702 ,  A61N2005/1021 ,  G01T1/1603 ,  G21G2001/0031

摘要： A nuclear medicine infusion system (10) may be used to generate and infuse radioactive liquid into a patient undergoing a diagnostic imaging procedure. In some examples, the infusion system includes a frame (30) that carries a radioisotope generator (52) that generates radioactive eluate via elution. The frame may also carry a beta detector (58) and a gamma detector (60). The beta detector can be positioned to measure beta emissions emitted from the radioactive eluate supplied by the generator. The gamma detector can be positioned to measure gamma emissions emitted from a portion of the radioactive eluate to evaluate a safety of the radioactive eluate delivered by the infusion system.

公开(公告)号：US11810685B2

公开(公告)日：2023-11-07

申请号：US17042355

申请日：2019-03-28

申请人： BRACCO DIAGNOSTICS INC.

发明人： Adrian Nunn

IPC分类号： G21G1/00 ,  A61B6/00 ,  A61M5/14 ,  A61M5/168 ,  G01T1/167

CPC分类号： G21G1/0005 ,  A61B6/4057 ,  A61B6/4258 ,  A61M5/1408 ,  A61M5/16827 ,  G01T1/167 ,  A61M2205/18 ,  A61M2205/702

摘要： An infusion system (10) including a radioisotope generator (52) that generates a radioactive eluate via an elution, an activity detector (58) configured to measure an activity of a first radioisotope in the radioactive eluate generated by the radioisotope generator, and a controller (80). The controller can track a cumulative volume of radioactive eluate generated by the radioisotope generator and also track the activity of the first radioisotope in the radioactive eluate generated by the radioisotope generator. The controller can determine a predicted volume of the radioactive eluate generated by the radioisotope generator at which the activity of the first radioisotope in the radioactive eluate will reach a threshold based on the tracked cumulative volume of the radioactive eluate and the tracked activity of the first radioisotope. This information can be useful for proactively removing the radioisotope generator from service and/or replacing the radioisotope generator with a fresh generator.

公开(公告)号：US11865298B2

公开(公告)日：2024-01-09

申请号：US16334887

申请日：2017-09-20

申请人： BRACCO DIAGNOSTICS INC.

发明人： Adrian Nunn ,  Clif Moyers ,  Andrew Schimmoeller ,  Brian Cherundolo ,  Tarah Bolas

IPC分类号： A61M5/00 ,  A61K51/12 ,  G21F5/015 ,  G21G1/00 ,  G21G4/08 ,  A61M5/14 ,  A61M5/162 ,  A61M5/168 ,  G01T1/20 ,  G21H5/02 ,  G01T7/00 ,  A61N5/10 ,  A61M5/142 ,  G01T1/16

CPC分类号： A61M5/007 ,  A61K51/121 ,  A61K51/1282 ,  A61M5/142 ,  A61M5/1408 ,  A61M5/162 ,  A61M5/16827 ,  A61M5/16881 ,  A61N5/1007 ,  G01T1/20 ,  G01T7/005 ,  G21F5/015 ,  G21G1/0005 ,  G21G4/08 ,  G21H5/02 ,  A61K2123/00 ,  A61M2205/18 ,  A61M2205/3313 ,  A61M2205/3389 ,  A61M2205/702 ,  A61N2005/1021 ,  G01T1/1603 ,  G21G2001/0031

摘要： An infusion system may include a strontium-rubidium radioisotope generator that generates a radioactive eluate via elution, a beta detector, a gamma detector, and a controller. The beta detector and the gamma detector may be positioned to measure beta emissions and gamma emissions, respectively, emitted from the radioactive eluate. In some examples, the controller is configured to determine an activity of rubidium in the radioactive eluate based on the beta emissions measured by the beta detector and determine an activity of strontium in the radioactive eluate based on the gamma emissions measured by the gamma detector.