公开(公告)号：US20170107202A1

公开(公告)日：2017-04-20

申请号：US15290167

申请日：2016-10-11

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： KAP-SUN YEUNG ,  Timothy P. Connolly ,  David B. Frennesson ,  Katharine A. Grant-Young ,  Piyasena Hewawasam ,  David R. Langley ,  Zhaoxing Meng ,  Eric Mull ,  Kyle E. Parcella ,  Mark George Saulnier ,  Li-Qiang Sun ,  Alan Xiangdong Wang ,  Ningning Xu ,  Juliang Zhu ,  Paul Michael Scola

IPC: C07D401/14 ,  A61K31/5377 ,  C07D213/85 ,  A61K31/4439 ,  C07D401/12 ,  A61K31/4545 ,  A61K31/44 ,  C07D471/04 ,  C07D405/14 ,  A61K31/454 ,  C07D403/12 ,  A61K31/4025 ,  A61K31/496 ,  C07D205/04 ,  A61K31/397 ,  A61K31/4427 ,  A61K31/4453 ,  C07D211/22 ,  A61K31/40 ,  C07D207/14 ,  C07D207/12 ,  A61K31/138 ,  C07C215/20 ,  C07D413/14 ,  C07D213/82 ,  C07D491/08 ,  C07D417/14 ,  A61K31/541 ,  C07D471/08 ,  C07D405/12 ,  A61K31/135 ,  C07D213/80 ,  C07D207/16 ,  C07D265/30 ,  A61K31/5375 ,  A61K31/166 ,  C07C235/46 ,  C07D417/12 ,  A61K45/06

Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.

公开(公告)号：US10745382B2

公开(公告)日：2020-08-18

申请号：US15290167

申请日：2016-10-11

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Kap-Sun Yeung ,  Timothy P. Connolly ,  David B. Frennesson ,  Katharine A. Grant-Young ,  Piyasena Hewawasam ,  David R. Langley ,  Zhaoxing Meng ,  Eric Mull ,  Kyle E. Parcella ,  Mark George Saulnier ,  Li-Qiang Sun ,  Alan Xiangdong Wang ,  Ningning Xu ,  Juliang Zhu ,  Paul Michael Scola

IPC: C07D401/14 ,  C07D213/71 ,  C07D455/02 ,  A61K31/135 ,  A61K31/138 ,  A61K31/166 ,  A61K31/397 ,  A61K31/40 ,  A61K31/4025 ,  A61K31/44 ,  A61K31/4427 ,  A61K31/4439 ,  A61K31/4453 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/496 ,  A61K31/5375 ,  A61K31/5377 ,  A61K31/541 ,  A61K45/06 ,  C07C215/20 ,  C07C235/46 ,  C07D205/04 ,  C07D207/12 ,  C07D207/14 ,  C07D207/16 ,  C07D211/22 ,  C07D213/80 ,  C07D213/82 ,  C07D213/85 ,  C07D265/30 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  C07D471/08 ,  C07D491/08

Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.