Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
    1.
    发明申请
    Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase 审中-公开
    核苷衍生物作为rna依赖性rna病毒聚合酶的抑制剂

    公开(公告)号:US20060264389A1

    公开(公告)日:2006-11-23

    申请号:US10521006

    申请日:2003-07-11

    IPC分类号: A61K31/7076 C07H19/22

    CPC分类号: C07H19/14 C07H19/22

    摘要: Thee present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA via replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or creating RNA-dependent RNA viral infection with the nucleoside compounds of the present invention.

    摘要翻译: 本发明提供作为RNA依赖性RNA病毒聚合酶抑制剂的核苷化合物及其某些衍生物。 这些化合物是通过复制的RNA依赖性RNA的抑制剂,并且可用于治疗RNA依赖性RNA病毒感染。 它们特别可用作丙型肝炎病毒(HCV)NS5B聚合酶的抑制剂,作为HCV复制的抑制剂和/或用于治疗丙型肝炎感染。 本发明还描述了单独或与其它对RNA依赖性RNA病毒感染(特别是HCV感染)有活性的试剂组合的药物组合物。 还公开了抑制RNA依赖性RNA聚合酶,抑制RNA依赖性RNA病毒复制和/或用本发明的核苷化合物产生RNA依赖性RNA病毒感染的方法。

    Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
    3.
    发明申请
    Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase 审中-公开
    核苷衍生物作为rna依赖性rna病毒聚合酶的抑制剂

    公开(公告)号:US20070004669A1

    公开(公告)日:2007-01-04

    申请号:US10517295

    申请日:2003-06-17

    摘要: The present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside compounds alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection with the nucleoside compounds of the present invention.

    摘要翻译: 本发明提供作为RNA依赖性RNA病毒聚合酶抑制剂的核苷化合物及其某些衍生物。 这些化合物是RNA依赖性RNA病毒复制的抑制剂,可用于治疗RNA依赖性RNA病毒感染。 它们特别可用作丙型肝炎病毒(HCV)NS5B聚合酶的抑制剂,作为HCV复制的抑制剂和/或用于治疗丙型肝炎感染。 本发明还描述了单独或与其它对RNA依赖性RNA病毒感染(特别是HCV感染)有活性的试剂组合的药物组合物。 还公开了本发明的核苷化合物抑制RNA依赖性RNA聚合酶,抑制RNA依赖性RNA病毒复制和/或治疗RNA依赖性RNA病毒感染的方法。

    Mobile platform for event registration
    6.
    发明授权
    Mobile platform for event registration 有权
    移动平台进行事件注册

    公开(公告)号:US08688571B2

    公开(公告)日:2014-04-01

    申请号:US13297123

    申请日:2011-11-15

    IPC分类号: G06Q10/00 G06Q99/00

    摘要: Method and systems of registering participants for an event at an event site are disclosed. Identification data specific to a participant encoded on a first token object is read with a mobile computing device. A query is generated from the mobile computing device to a remote event registration system for prior registration data based upon at least a subset of the received identification data. The prior registration data is received on the mobile computing device. A first subset of the prior registration data is transmitted to a local event registration system, and a payment success indicator is received upon successful payment processing. Registrant identification data is generated by the local event registration system in response to recording the first subset of the prior registration data and the payment success indicator.

    摘要翻译: 公开了在事件现场注册事件的参与者的方法和系统。 使用移动计算设备读取特定于在第一令牌对象上编码的参与者的识别数据。 基于所接收的标识数据的至少一个子集,从移动计算设备向远程事件注册系统生成用于先前注册数据的查询。 在移动计算设备上接收先前的注册数据。 先前注册数据的第一个子集被发送到本地事件注册系统,并且在成功的支付处理之后接收到支付成功指示符。 响应于记录先前注册数据的第一子集和支付成功指示符,由本地事件注册系统生成注册人标识数据。

    Sliding picture frame
    8.
    发明授权
    Sliding picture frame 失效
    滑动相框

    公开(公告)号:US06490818B1

    公开(公告)日:2002-12-10

    申请号:US09694083

    申请日:2000-10-20

    IPC分类号: G09F1100

    CPC分类号: G09F11/30 A47G1/065 G09F11/00

    摘要: A versatile system which includes a display unit by which a plurality of image works selected from photographs, paintings, newspaper articles, pictures, images, prints, designs, sports memorabilia, certificates, awards, and diplomas may be viewed simultaneously or individually, as selected by the viewer. A display unit stores a plurality of image works for selective viewing by an observer by virtue of each image works being mounted on a slidable carrier, which may be slid within a framework to enable or disable viewing of image works which may be disposed behind a given slidable carrier.

    摘要翻译: 包括显示单元,通过该显示单元可选择从照片,油画,报纸文章,图片,图像,打印,设计,运动纪念品,证书,奖励和文凭中选择的多个图像作品被选择同时或单独地被选择 由观众。 显示单元存储多个用于由观察者选择性地观看的图像作品,其中每个图像作品被安装在可滑动的载体上,其可以在框架内滑动以使得或禁止观看可以设置在给定的后面的图像作品 可滑动的载体。