公开(公告)号：US08232388B2

公开(公告)日：2012-07-31

申请号：US12341689

申请日：2008-12-22

申请人： Baptiste Boit ,  Pierrick Duflot ,  José Lis

发明人： Baptiste Boit ,  Pierrick Duflot ,  José Lis

IPC分类号： C07H3/04 ,  A61K47/26 ,  C13B30/02

CPC分类号： C07H15/04 ,  A23G1/40 ,  A23G3/42 ,  A23G4/10 ,  A23L27/34

摘要： The invention relates to a granulated maltitol of concentration greater than or equal to 97%, preferably between 98 and 99%, characterized in that it has a water content less than 1%, preferably less than 0.5%, more preferably less than or equal to 0.4%, a compressibility greater than or equal to 300 N, preferably between 300 and 500 N, and a hygroscopicity less than or equal to 2.5%, preferably between 0.15 and 2.5%.

摘要翻译： 本发明涉及浓度大于或等于97％，优选98至99％的粒状麦芽糖醇，其特征在于其含水量小于1％，优选小于0.5％，更优选小于或等于 0.4％，压缩率大于或等于300N，优选300至500N，吸湿性小于或等于2.5％，优选0.15至2.5％。

公开(公告)号：US08101806B2

公开(公告)日：2012-01-24

申请号：US12375464

申请日：2007-07-23

申请人： Pierrick Duflot ,  Baptiste Boit ,  Philippe Lefevre ,  José Lis

发明人： Pierrick Duflot ,  Baptiste Boit ,  Philippe Lefevre ,  José Lis

IPC分类号： C07C31/18 ,  A23L1/236

CPC分类号： C07C31/26 ,  A23L27/34 ,  A23L29/37 ,  A23P10/20 ,  A61K9/1623 ,  A61K9/2018 ,  Y10T428/2982

摘要： The present invention relates to a granulated sorbitol of essentially γ crystalline form and having a high sorbitol content, characterized in that it has a specific surface area, determined according to the BET method, of greater than or equal to 2 m2/g, preferably of between 2.2 and 4 m2/g, and even more preferably of between 2.5 and 3.5 m2/g, a compressibility of between 200 and 400 N, preferably of between 250 and 350 N, and a volume-average diameter, measured by laser diffraction particle sizing using a dry-system module, of between 260 and 1000 μm, preferably of between 260 and 500 μm, and even more preferably of between 260 and 350 μm.

摘要翻译： 本发明涉及一种基本为γ晶形并具有高山梨糖醇含量的颗粒状山梨糖醇，其特征在于其具有根据BET法测定的比表面积大于或等于2m 2 / g，优选为 在2.2至4m 2 / g之间，甚至更优选2.5至3.5m 2 / g的压缩性，200至400N之间的压缩性，优选250至350N，以及通过激光衍射颗粒测量的体积平均直径 使用干式系统模块的尺寸在260和1000μm之间，优选在260和500μm之间，甚至更优选在260和350μm之间。

公开(公告)号：US08518185B2

公开(公告)日：2013-08-27

申请号：US13529063

申请日：2012-06-21

申请人： Baptiste Boit ,  Pierrick Duflot ,  Jose Lis

发明人： Baptiste Boit ,  Pierrick Duflot ,  Jose Lis

IPC分类号： C13B30/02 ,  C07H1/06 ,  C07H15/04

CPC分类号： C07H15/04 ,  A23G1/40 ,  A23G3/42 ,  A23G4/10 ,  A23L27/34

摘要： Method of producing granulated maltitol, including the stages: preparing maltitol syrup having less than 50 wt.% dry matter and greater than 70 wt.% maltitol, introducing to a fluidized air bed granulator, a pulverulent bed of crystallized maltitol with a concentration at least equal to 99 wt.% and a mean diameter between 30 and 100 μm, controlling the air inlet temperature between 100 and 120° C. and air velocity between 1 and 2 m/s, fine spraying the maltitol syrup into the granulator, at between 35 and 45° C., onto the moving pulverulent bed; the bed being between 30 and 60° C.; the mass of the bed representing constantly at least 2.5 times the mass of the sprayed syrup, drying, after fine spraying, by raising the air temperature below the melting point of maltitol to obtain a bed temperature between 70 and 80° C., cooling the granulated maltitol to at most 25° C. and collecting.

摘要翻译： 制备粒状麦芽糖醇的方法，包括以下步骤：制备具有小于50重量％干物质和大于70重量％麦芽糖醇的麦芽糖醇糖浆，向流化床制粒机中引入浓度至少为微量的结晶麦芽糖醇粉末床 等于99重量％，平均直径在30和100微米之间，控制空气入口温度在100和120℃之间，空气速度在1和2米/秒之间，将麦芽糖醇糖浆细粉末放入造粒机中间 35和45℃，到移动的粉状床上; 床在30和60°C之间; 床的质量不断地表示喷雾糖浆的质量的至少2.5倍，在细喷雾之后干燥，通过将空气温度升高到低于麦芽糖醇的熔点以获得70-80℃的床温度，冷却 颗粒状麦芽糖醇至多25℃并收集。

公开(公告)号：US20090007903A1

公开(公告)日：2009-01-08

申请号：US11995036

申请日：2006-06-28

申请人： Pierrick Duflot ,  Baptiste Boit

发明人： Pierrick Duflot ,  Baptiste Boit

IPC分类号： C13F1/02 ,  C13F1/06

CPC分类号： A23G3/346 ,  A23G3/42 ,  A23G3/50 ,  A23L27/34 ,  A23L29/35 ,  A23L29/37 ,  A23V2002/00 ,  A61K9/1623 ,  A61K9/1682 ,  A61K9/2018 ,  C07C29/78 ,  C07C31/26 ,  Y10S47/09 ,  A23G2200/06 ,  A23V2250/6422 ,  A23V2250/64 ,  C07C31/18 ,  C07C31/225 ,  C07C31/24

摘要： A method for producing a powder containing xylitol crystal particles and another polyol including a mixture containing a xylitol syrup and another polyol, whose dry material content is equal to or greater than 95% by weight, xylitol content ranges from 85 to 97.5% by weight and the other polyol content ranges at least from 15 to 2.5% by weight with respects to the dry material. The method includes: obtaining the mixture by simultaneously dispersing the xylitol and the other polyol syrup and xylitol-containing germs in an open rotating vessel containing xylitol-based granules, mixing the xylitol and the other polyol syrup and xylitol-containing germs on the surface of the xylitol-containing germs contained in the vessel, removing the xylitol-based granules and the other polyol from the vessel and crystallizing the xylitol and other polyol contained in the granules.

摘要翻译： 一种含有木糖醇晶体颗粒的粉末和含有木糖醇糖浆和另一种多元醇的混合物的其它多元醇的干燥物质含量等于或大于95重量％的木糖醇含量为85-97.5重量％的方法， 相对于干燥材料，其它多元醇含量为至少15至2.5重量％。 该方法包括：通过将木糖醇和其它多元醇糖浆和含木糖醇的细菌同时分散在含有木糖醇基颗粒的开放旋转容器中，将木糖醇和其它多元醇糖浆和含木糖醇的细菌混合在表面上， 包含在容器中的含木糖醇的细菌，从容器中除去木糖醇基颗粒和其它多元醇，并使包含在颗粒中的木糖醇和其它多元醇结晶。

公开(公告)号：US08112935B2

公开(公告)日：2012-02-14

申请号：US11995036

申请日：2006-06-28

申请人： Pierrick Duflot ,  Baptiste Boit

发明人： Pierrick Duflot ,  Baptiste Boit

IPC分类号： A01C1/00

CPC分类号： A23G3/346 ,  A23G3/42 ,  A23G3/50 ,  A23L27/34 ,  A23L29/35 ,  A23L29/37 ,  A23V2002/00 ,  A61K9/1623 ,  A61K9/1682 ,  A61K9/2018 ,  C07C29/78 ,  C07C31/26 ,  Y10S47/09 ,  A23G2200/06 ,  A23V2250/6422 ,  A23V2250/64 ,  C07C31/18 ,  C07C31/225 ,  C07C31/24

摘要： A method for producing a powder containing xylitol crystal particles and another polyol including a mixture containing a xylitol syrup and another polyol, whose dry material content is equal to or greater than 95% by weight, xylitol content ranges from 85 to 97.5% by weight and the other polyol content ranges at least from 15 to 2.5% by weight with respects to the dry material. The method includes: obtaining the mixture by simultaneously dispersing the xylitol and the other polyol syrup and xylitol-containing germs in an open rotating vessel containing xylitol-based granules, mixing the xylitol and the other polyol syrup and xylitol-containing germs on the surface of the xylitol-containing germs contained in the vessel, removing the xylitol-based granules and the other polyol from the vessel and crystallizing the xylitol and other polyol contained in the granules.

摘要翻译： 一种含有木糖醇晶体颗粒的粉末和含有木糖醇糖浆和另一种多元醇的混合物的其它多元醇的干燥物质含量等于或大于95重量％的木糖醇含量为85-97.5重量％的方法， 相对于干燥材料，其它多元醇含量为至少15至2.5重量％。 该方法包括：通过将木糖醇和其它多元醇糖浆和含木糖醇的细菌同时分散在含有木糖醇基颗粒的开放旋转容器中，将木糖醇和其它多元醇糖浆和含木糖醇的细菌混合在表面上， 包含在容器中的含木糖醇的细菌，从容器中除去木糖醇基颗粒和其它多元醇，并使包含在颗粒中的木糖醇和其它多元醇结晶。

公开(公告)号：US20090324794A1

公开(公告)日：2009-12-31

申请号：US12375464

申请日：2007-07-23

申请人： Pierrick Duflot ,  Baptiste Boit ,  Philippe Lefevre ,  Jose Lis

发明人： Pierrick Duflot ,  Baptiste Boit ,  Philippe Lefevre ,  Jose Lis

IPC分类号： A23L1/236 ,  C07C31/18 ,  B32B1/00

CPC分类号： C07C31/26 ,  A23L27/34 ,  A23L29/37 ,  A23P10/20 ,  A61K9/1623 ,  A61K9/2018 ,  Y10T428/2982

摘要： The present invention relates to a granulated sorbitol of essentially γ crystalline form and having a high sorbitol content, characterized in that it has a specific surface area, determined according to the BET method, of greater than or equal to 2 m2/g, preferably of between 2.2 and 4 m2/g, and even more preferably of between 2.5 and 3.5 m2/g, a compressibility of between 200 and 400 N, preferably of between 250 and 350 N, and a volume-average diameter, measured by laser diffraction particle sizing using a dry-system module, of between 260 and 1000 μm, preferably of between 260 and 500 μm, and even more preferably of between 260 and 350 μm.

摘要翻译： 本发明涉及一种基本为γ晶型并具有高山梨糖醇含量的颗粒状山梨糖醇，其特征在于其具有根据BET法测定的比表面积大于或等于2m 2 / g，优选为 在2.2至4m 2 / g之间，甚至更优选2.5至3.5m 2 / g的压缩性，200至400N之间的压缩性，优选250至350N，以及通过激光衍射颗粒测量的体积平均直径 使用干系统模块的尺寸为260至1000μm，优选为260至500μm，甚至更优选为260至350μm。

公开(公告)号：US20120164266A1

公开(公告)日：2012-06-28

申请号：US13393590

申请日：2010-08-06

申请人： Baptiste Boit ,  Philippe Lefevre ,  Jose Lis ,  Dominique Ortiz De Zarate

发明人： Baptiste Boit ,  Philippe Lefevre ,  Jose Lis ,  Dominique Ortiz De Zarate

IPC分类号： A23G4/06

CPC分类号： A23G4/025 ,  A23G4/062 ,  A23G4/10 ,  A23G2210/00 ,  A23V2002/00 ,  A23V2200/22 ,  A23V2200/254 ,  A23V2250/5118 ,  A23V2250/5114

摘要： Disclosed is a method of production of chewing gum including a step of mixing the ingredients, a step of extrusion of the mixture, a step of dusting with a dusting powder, a rolling step and a forming-cutting step, wherein the dusting powder includes a pulverulent composition containing from 28% to 0.1%, preferably from 25% to 1% of particles of diameter below 75 μm and of hygroscopicity between 0.01 and 5%, the pulverulent composition including at least one polyol. Also disclosed is the chewing gum obtained by application of the method.

摘要翻译： 公开了一种生产口香糖的方法，包括混合成分的步骤，混合物的挤出步骤，用粉尘粉尘的步骤，轧制步骤和成形切割步骤，其中除尘粉末包括 所述粉末组合物含有28％至0.1％，优选25％至1％的直径小于75μm的颗粒和吸湿性为0.01％至5％的粉状组合物，粉状组合物包含至少一种多元醇。 还公开了通过应用该方法获得的口香糖。

公开(公告)号：US20110111037A1

公开(公告)日：2011-05-12

申请号：US13001501

申请日：2009-07-02

申请人： Baptiste Boit ,  Philippe Lefevre ,  Damien Passe

发明人： Baptiste Boit ,  Philippe Lefevre ,  Damien Passe

IPC分类号： A61K9/14 ,  A61K31/5415 ,  A61K31/375 ,  A61P7/10 ,  A61K33/16

CPC分类号： A61K9/0056 ,  A61J3/10 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/2018 ,  A61K9/2059

摘要： Coagglomerates of mannitol, whose laser volume-average diameter D4,3 is between 1 and 200 μm, and of granular starch, are characterized in that they have a disintegration behaviour determined according to a test A such that the relaxation time measured is between 30 and 100 seconds and the swelling force is between 0.8 and 3.0 N.

摘要翻译： 其激光体积平均直径D4,3为1至200μm的甘露醇和颗粒状淀粉的团聚体的特征在于它们具有根据试验A确定的崩解行为，使得测得的弛豫时间在30和 100秒，溶胀力在0.8和3.0N之间。

公开(公告)号：US09937131B2

公开(公告)日：2018-04-10

申请号：US13318211

申请日：2010-04-28

申请人： Baptiste Boit ,  Alain Francois ,  Philippe Lefevre ,  Damien Passe

发明人： Baptiste Boit ,  Alain Francois ,  Philippe Lefevre ,  Damien Passe

IPC分类号： A61K9/20 ,  A61K9/48

CPC分类号： A61K9/2018 ,  A61K9/2059 ,  A61K9/4858 ,  A61K9/4866

摘要： Co-agglomerates of crystalline mannitol and granular starch, characterized in that they have a compressibility, as determined according to a test A, higher than 120 N, and preferably of 200 to 450 N, and a flow time, as determined according to a test B, of 3 to 15 seconds, and preferably of 4 to 8 seconds.

公开(公告)号：US09234049B2

公开(公告)日：2016-01-12

申请号：US13880506

申请日：2011-11-02

申请人： Baptiste Boit ,  Fabrice Buquet ,  Gregory Le Bihan ,  Philippe Lefevre

发明人： Baptiste Boit ,  Fabrice Buquet ,  Gregory Le Bihan ,  Philippe Lefevre

IPC分类号： C08B31/12 ,  A61K47/26 ,  A61K47/36 ,  C08L3/02 ,  C08L5/00 ,  A61K47/38 ,  C08B11/08 ,  C08B37/00

CPC分类号： C08B31/12 ,  A61K47/26 ,  A61K47/36 ,  A61K47/38 ,  C08B11/08 ,  C08B37/00 ,  C08B37/0084 ,  C08L3/02 ,  C08L5/00 ,  Y10T428/2982

摘要： A powder of cold-soluble polysaccharide and polyol, which is highly viscous in water and suitable for direct compression, and a method for preparing the powder and uses thereof are described, the powder being notably intended for preparing solid forms with controlled release of an active principle.

摘要翻译： 描述了在水中高粘度并适于直接压缩的冷溶性多糖和多元醇粉末以及制备粉末及其用途的方法，该粉末特别用于制备具有活性物质的受控释放的固体形式 原理。