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    Pharmaceutical agent delivery in a stimulating medical device
    2.
    发明授权
    Pharmaceutical agent delivery in a stimulating medical device 有权
    药剂在刺激性医疗器械中的输送

    公开(公告)号：US08892201B2

    公开(公告)日：2014-11-18

    申请号：US13916865

    申请日：2013-06-13

    申请人： John L. Parker ,  James F. Patrick ,  Paul Carter

    发明人： John L. Parker ,  James F. Patrick ,  Paul Carter

    IPC分类号： A61N1/18 ,  A61N1/36 ,  A61N1/05 ,  A61F11/00

    CPC分类号： A61N1/36032 ,  A61F11/00 ,  A61N1/0541 ,  A61N1/36036

    摘要： A stimulating medical device comprising a stimulating assembly implantable proximate to nerve cells of a recipient having at least one agent delivery port and a plurality of electrical contacts; an electrical stimulation controller configured to generate electrical stimulation signals for application to a first population of the nerve cells via one or more of the plurality of electrical contacts; a pharmaceutical agent source configured to provide a pharmaceutical agent to the at least one delivery port for application to a second population of the nerve cells; and a pharmaceutical agent controller configured to control one or more of the pharmaceutical agent source and the at least one delivery port to cause selective application of the pharmaceutical agent to the second population of nerve cells.

    摘要翻译： 一种刺激性医疗装置，包括可接近于具有至少一个药剂输送口和多个电触头的受体的神经细胞植入的刺激组件; 电刺激控制器，被配置为产生电刺激信号，以经由多个电触点中的一个或多个施加到神经细胞的第一群体; 药剂源，被配置为向所述至少一个递送端口提供药剂以施用于所述神经细胞的第二群体; 以及药剂控制器，其被配置为控制所述药剂源和所述至少一个递送端口中的一个或多个，以引起所述药剂选择性施用于所述第二神经细胞群。

    PHARMACEUTICAL AGENT DELIVERY IN A STIMULATING MEDICAL DEVICE
    3.
    发明申请
    PHARMACEUTICAL AGENT DELIVERY IN A STIMULATING MEDICAL DEVICE 有权
    刺激性医疗器械中的药物代理

    公开(公告)号：US20140058314A1

    公开(公告)日：2014-02-27

    申请号：US13916865

    申请日：2013-06-13

    申请人： John L. Parker ,  James F. Patrick ,  Paul Carter

    发明人： John L. Parker ,  James F. Patrick ,  Paul Carter

    IPC分类号： A61N1/36 ,  A61F11/00

    CPC分类号： A61N1/36032 ,  A61F11/00 ,  A61N1/0541 ,  A61N1/36036

    摘要： A stimulating medical device comprising a stimulating assembly implantable proximate to nerve cells of a recipient having at least one agent delivery port and a plurality of electrical contacts; an electrical stimulation controller configured to generate electrical stimulation signals for application to a first population of the nerve cells via one or more of the plurality of electrical contacts; a pharmaceutical agent source configured to provide a pharmaceutical agent to the at least one delivery port for application to a second population of the nerve cells; and a pharmaceutical agent controller configured to control one or more of the pharmaceutical agent source and the at least one delivery port to cause selective application of the pharmaceutical agent to the second population of nerve cells.

    摘要翻译： 一种刺激性医疗装置，包括可接近于具有至少一个药剂输送口和多个电触头的受体的神经细胞植入的刺激组件; 电刺激控制器，被配置为产生电刺激信号，以经由多个电触点中的一个或多个施加到神经细胞的第一群体; 药剂源，被配置为向所述至少一个递送端口提供药剂以施用于所述神经细胞的第二群体; 以及药剂控制器，其被配置为控制所述药剂源和所述至少一个递送端口中的一个或多个，以引起所述药剂选择性施用于所述第二神经细胞群。

    Knitted electrode assembly and integrated connector for an active implantable medical device
    4.
    发明授权
    Knitted electrode assembly and integrated connector for an active implantable medical device 有权
    用于有源植入式医疗器械的针织电极组件和集成连接器

    公开(公告)号：US08897888B2

    公开(公告)日：2014-11-25

    申请号：US12549457

    申请日：2009-08-28

    申请人： John L. Parker ,  David Robinson

    发明人： John L. Parker ,  David Robinson

    IPC分类号： A61N1/05 ,  A61M25/00 ,  A61N1/375

    CPC分类号： A61N1/05 ,  A61M25/0009 ,  A61N1/0472 ,  A61N1/0484 ,  A61N1/0529 ,  A61N1/375

    摘要： An active implantable medical device (AIMD). The AIMD comprises: a knitted electrode assembly comprising: at least one biocompatible, electrically non-conductive filament arranged in substantially parallel rows each stitched to an adjacent row, and at least one biocompatible, electrically conductive filament having a first end intertwined with a first row of the at least one non-conductive filament, and a second end intertwined with a second row of the at least one non-conductive filament, wherein the first and second rows are spaced from one another.

    摘要翻译： 主动植入医疗器械（AIMD）。 AIMD包括：编织电极组件，其包括：至少一个生物相容的，不导电的细丝，其布置成大致平行的行，每个行缝合到相邻排，以及至少一个生物相容的导电细丝，其具有缠绕在第一排 的所述至少一个非导电细丝，以及与所述至少一个非导电细丝的第二排缠绕的第二端，其中所述第一和第二行彼此间隔开。

    FORMING FEEDTHROUGHS FOR HERMETICALLY SEALED HOUSINGS USING TWO-MATERIAL POWDER INJECTION MOLDING
    5.
    发明申请
    FORMING FEEDTHROUGHS FOR HERMETICALLY SEALED HOUSINGS USING TWO-MATERIAL POWDER INJECTION MOLDING 有权
    使用两种粉末注射成型制成的密封外壳的成型工艺

    公开(公告)号：US20120319319A1

    公开(公告)日：2012-12-20

    申请号：US13512172

    申请日：2010-11-26

    申请人： John L. Parker ,  David Robinson ,  David Thomas ,  Mark Fretz

    发明人： John L. Parker ,  David Robinson ,  David Thomas ,  Mark Fretz

    IPC分类号： B29C45/16

    CPC分类号： A61N1/3754 ,  A61N1/3756 ,  B22F3/225 ,  B28B1/24 ,  B29C33/302 ,  B29C45/0001 ,  C04B2111/00137 ,  C04B2235/6022

    摘要： Methods of forming a feedthrough using a mold that defines a cavity when closed and includes one or more cores configured to move in and out of the mold cavity. The methods include injecting non-electrically conductive powder injection molding (PIM) feedstock into the mold cavity to form an insulative body around a portion of each of the cores disposed in the mold cavity, removing each of the cores from the insulative body to form one or more core cavities in the insulative body, injecting electrically conductive PIM feedstock into the core cavities to form one or more conductors in the core cavities, respectively, and sintering the insulative body and the conductors to form the feedthrough.

    摘要翻译： 使用模具形成馈通的方法，所述模具在关闭时限定空腔，并且包括配置成移入和移出模腔的一个或多个芯体。 所述方法包括将非导电粉末注射成型（PIM）原料注入到模腔中以在设置在模腔中的每个芯的一部分周围形成绝缘体，从绝缘体去除每个芯以形成一个 或更多个芯腔，分别将导电PIM原料注入到芯腔中以在芯腔中形成一个或多个导体，并且烧结绝缘体和导体以形成馈通。

    MULTI-MODE HEARING PROSTHESIS
    6.
    发明申请
    MULTI-MODE HEARING PROSTHESIS 审中-公开
    多模式听觉预测

    公开(公告)号：US20120215057A1

    公开(公告)日：2012-08-23

    申请号：US13454732

    申请日：2012-04-24

    申请人： John L. Parker

    发明人： John L. Parker

    IPC分类号： A61F11/04 ,  H04R25/00

    CPC分类号： H04R25/606 ,  H04R25/353 ,  H04R2430/03 ,  H04R2460/13

    摘要： A multi-mode hearing prosthesis for enhancing the hearing of a recipient, comprising: a sound input element configured to receive a sound signal component; a frequency spectral analysis module configured to analyze the sound signal component and to categorize the component into at least a high- or lower-frequency component; a bone conduction processor configured to generate bone conduction stimulation signals from at least one of said high- and lower-frequency component for bone conduction stimulation of the recipient's skull; and a second stimulation processor configured to generate auditory stimulation signals from at least one of said high- and lower-frequency components for stimulating the recipient.

    摘要翻译： 一种用于增强接收者的听力的多模式听觉假体，包括：声音输入元件，被配置为接收声音信号分量; 频谱分析模块，被配置为分析所述声音信号分量并将所述分量分类为至少高频或低频分量; 骨传导处理器被配置为从所述高频和低频分量中的至少一个产生骨传导刺激信号，用于接受者头骨的骨传导刺激; 以及第二刺激处理器，被配置为从所述高频和低频分量中的至少一个产生听觉刺激信号，以刺激接收者。

    KNITTED ELECTRODE ASSEMBLY FOR AN ACTIVE IMPLANTABLE MEDICAL DEVICE
    7.
    发明申请
    KNITTED ELECTRODE ASSEMBLY FOR AN ACTIVE IMPLANTABLE MEDICAL DEVICE 有权
    用于有源可植入医疗装置的针刺电极组件

    公开(公告)号：US20100070008A1

    公开(公告)日：2010-03-18

    申请号：US12549899

    申请日：2009-08-28

    申请人： John L. Parker ,  David Robinson

    发明人： John L. Parker ,  David Robinson

    IPC分类号： A61N1/00 ,  D04B1/00 ,  D04B1/22

    CPC分类号： A61N1/05 ,  A61M25/0009 ,  A61N1/0472 ,  A61N1/0484 ,  A61N1/0529 ,  A61N1/375

    摘要： An active implantable medical device (AIMD). The AIMD comprises an electronics module; and a knitted electrode assembly comprising: at least one biocompatible, electrically non-conductive filament arranged in substantially parallel rows each stitched to an adjacent row, and at least one biocompatible, electrically conductive filament intertwined with the at least one non-conductive filament, and configured to be electrically connected to the electronics module.

    摘要翻译： 主动植入医疗器械（AIMD）。 AIMD包括电子模块; 以及针织电极组件，其包括：至少一个生物相容的，不导电的细丝，其布置成大致平行的行，每个线缝合到相邻的行，以及与所述至少一个非导电细丝缠结的至少一个生物相容的导电细丝，以及 被配置为电连接到电子模块。

    MULTI-MODE HEARING PROSTHESIS
    8.
    发明申请
    MULTI-MODE HEARING PROSTHESIS 审中-公开
    多模式听觉预测

    公开(公告)号：US20090292161A1

    公开(公告)日：2009-11-26

    申请号：US12353957

    申请日：2009-01-14

    申请人： John L. Parker

    发明人： John L. Parker

    IPC分类号： A61F11/04 ,  H04R25/00

    CPC分类号： H04R25/606 ,  H04R25/353 ,  H04R2430/03 ,  H04R2460/13

    摘要： A multi-mode hearing prosthesis for enhancing the hearing of a recipient, comprising: a sound input element configured to receive a sound signal component; a frequency spectral analysis module configured to analyze the sound signal component and to categorize the component into at least a high- or lower-frequency component; a bone conduction processor configured to generate bone conduction stimulation signals from at least one of said high- and lower-frequency component for bone conduction stimulation of the recipient's skull; and a second stimulation processor configured to generate auditory stimulation signals from at least one of said high- and lower-frequency components for stimulating the recipient.

    摘要翻译： 一种用于增强接收者的听力的多模式听觉假体，包括：声音输入元件，被配置为接收声音信号分量; 频谱分析模块，被配置为分析所述声音信号分量并将所述分量分类为至少高频或低频分量; 骨传导处理器被配置为从所述高频和低频分量中的至少一个产生骨传导刺激信号，用于接受者头骨的骨传导刺激; 以及第二刺激处理器，被配置为从所述高频和低频分量中的至少一个产生听觉刺激信号，以刺激接收者。

    Methods for maintaining low impedance of electrodes
    10.
    发明授权
    Methods for maintaining low impedance of electrodes 失效
    维持电极低阻抗的方法

    公开(公告)号：US07519435B2

    公开(公告)日：2009-04-14

    申请号：US11159256

    申请日：2005-06-23

    申请人： John L. Parker ,  Dusan Milojevic

    发明人： John L. Parker ,  Dusan Milojevic

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0541 ,  A61L31/10 ,  A61N1/36036 ,  B82Y30/00 ,  C08L71/02

    摘要： An implantable tissue-stimulating device for an implantee. The device comprising an elongate member having at least one electrode. At least a portion of the device is coated with a coating that at least partially inhibits adhesion of organic molecules to the device following implantation.

    摘要翻译： 用于植入物的可植入组织刺激装置。 该装置包括具有至少一个电极的细长构件。 该装置的至少一部分涂覆有至少部分地抑制植入后有机分子与器件粘附的涂层。