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    Water extractable ophthalmic devices
    1.
    发明授权
    Water extractable ophthalmic devices 有权

    公开(公告)号：US11022722B2

    公开(公告)日：2021-06-01

    申请号：US16415281

    申请日：2019-05-17

    申请人： Bausch & Lomb Incorporated

    发明人： Ivan M. Nuñez ,  Katie L. Poetz ,  Lynn Coullard ,  Alok Kumar Awasthi ,  Analuz Mark ,  Joseph W. Hoff ,  Andrew J. Hoteling

    IPC分类号： G02B1/04 ,  C08L83/04 ,  C08K5/34 ,  C08L33/10 ,  C08K5/3412

    摘要： A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more organosilicon-containing block copolymers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.

    WATER EXTRACTABLE OPHTHALMIC DEVICES
    3.
    发明申请
    WATER EXTRACTABLE OPHTHALMIC DEVICES 审中-公开

    公开(公告)号：US20200012015A1

    公开(公告)日：2020-01-09

    申请号：US16415281

    申请日：2019-05-17

    申请人： Bausch & Lomb Incorporated

    发明人： Ivan M. Nuñez ,  Katie L. Poetz ,  Lynn Coullard ,  Alok Kumar Awasfhi ,  Analuz Mark ,  Joseph W. Hoff ,  Andrew J. Hoteling

    IPC分类号： G02B1/04 ,  C08L83/04

    摘要： A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more organosilicon-containing block copolymers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.

    HIGH WATER CONTENT OPHTHALMIC DEVICES
    4.
    发明申请
    HIGH WATER CONTENT OPHTHALMIC DEVICES 审中-公开

    公开(公告)号：US20200049857A1

    公开(公告)日：2020-02-13

    申请号：US16100693

    申请日：2018-08-10

    申请人： Bausch & Lomb Incorporated

    发明人： Ivan M. Nuñez ,  Katie L. Poetz ,  Joseph W. Hoff ,  Judith Chapman Morgan

    IPC分类号： G02B1/04 ,  C07C269/00 ,  C08L39/06 ,  C08F26/10

    摘要： An ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) a major amount of one or more first non-silicone-containing hydrophilic monomers; (b) one or more hydrophobic monomers; and (c) a crosslinking agent mixture comprising (i) one or more di-, tri- or tetra(meth)acrylate-containing crosslinking agents and (ii) one or more di-, tri- or tetracarbamate-containing crosslinking agents, wherein the ophthalmic device has an equilibrium water content of at least about 65 weight percent.