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公开(公告)号:US11897985B2
公开(公告)日:2024-02-13
申请号:US17729181
申请日:2022-04-26
IPC分类号: B29D11/02 , C08F226/10 , C08F230/08 , C08J3/24 , B29D11/00 , C08J3/075 , G02B1/04
CPC分类号: C08F226/10 , B29D11/00134 , C08J3/075 , C08J3/24 , G02B1/043 , B29K2039/06 , C08F2800/20 , C08F2810/20
摘要: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more non-bulky organosilicon-containing monomers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
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公开(公告)号:US20220251269A1
公开(公告)日:2022-08-11
申请号:US17729181
申请日:2022-04-26
IPC分类号: C08F226/10 , B29D11/00 , C08J3/075 , C08J3/24 , G02B1/04
摘要: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more non-bulky organosilicon-containing monomers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
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公开(公告)号:US11022722B2
公开(公告)日:2021-06-01
申请号:US16415281
申请日:2019-05-17
发明人: Ivan M. Nuñez , Katie L. Poetz , Lynn Coullard , Alok Kumar Awasthi , Analuz Mark , Joseph W. Hoff , Andrew J. Hoteling
IPC分类号: G02B1/04 , C08L83/04 , C08K5/34 , C08L33/10 , C08K5/3412
摘要: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more organosilicon-containing block copolymers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
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公开(公告)号:US20200049857A1
公开(公告)日:2020-02-13
申请号:US16100693
申请日:2018-08-10
IPC分类号: G02B1/04 , C07C269/00 , C08L39/06 , C08F26/10
摘要: An ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) a major amount of one or more first non-silicone-containing hydrophilic monomers; (b) one or more hydrophobic monomers; and (c) a crosslinking agent mixture comprising (i) one or more di-, tri- or tetra(meth)acrylate-containing crosslinking agents and (ii) one or more di-, tri- or tetracarbamate-containing crosslinking agents, wherein the ophthalmic device has an equilibrium water content of at least about 65 weight percent.
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公开(公告)号:US20190233593A1
公开(公告)日:2019-08-01
申请号:US16246715
申请日:2019-01-14
发明人: Ivan M. Nuñez , Katie L. Poetz , Andrew J. Hoteling , Joseph W. Hoff , Lynn Coullard , Analuz Mark , Keyla M. Cubi , Joseph A. McGee
IPC分类号: C08G77/388 , C08G77/26 , C08G77/20 , A61L27/18
CPC分类号: C08G77/388 , A61L27/18 , C08G77/20 , C08G77/26 , C08G77/38 , C08G77/70 , C08L83/08 , C08K5/09 , C08K5/17
摘要: A method is disclosed which involves the steps of (a) reacting a polysiloxane prepolymer having reactive functional end groups with a non-free radical polymerizable reactive end-capping agent; and (b) reacting the reaction product of step (a) with a free radical polymerizable reactive end-capping agent.
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公开(公告)号:US11345773B2
公开(公告)日:2022-05-31
申请号:US16376136
申请日:2019-04-05
IPC分类号: C08F220/10 , C08J3/24 , G02B1/04 , C08F226/10 , B29D11/00 , C08J3/075
摘要: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more non-bulky organosilicon-containing monomers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
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公开(公告)号:US10816698B2
公开(公告)日:2020-10-27
申请号:US16100693
申请日:2018-08-10
IPC分类号: G02B1/04 , C07C269/00 , C08F26/10 , C08L39/06 , G02C7/04 , C08F220/18
摘要: An ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) a major amount of one or more first non-silicone-containing hydrophilic monomers; (b) one or more hydrophobic monomers; and (c) a crosslinking agent mixture comprising (i) one or more di-, tri- or tetra(meth)acrylate-containing crosslinking agents and (ii) one or more di-, tri- or tetracarbamate-containing crosslinking agents, wherein the ophthalmic device has an equilibrium water content of at least about 65 weight percent.
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公开(公告)号:US20200012015A1
公开(公告)日:2020-01-09
申请号:US16415281
申请日:2019-05-17
发明人: Ivan M. Nuñez , Katie L. Poetz , Lynn Coullard , Alok Kumar Awasfhi , Analuz Mark , Joseph W. Hoff , Andrew J. Hoteling
摘要: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more organosilicon-containing block copolymers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
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公开(公告)号:US20190352443A1
公开(公告)日:2019-11-21
申请号:US16376136
申请日:2019-04-05
IPC分类号: C08F226/10 , C08J3/075 , C08J3/24 , B29D11/00 , G02B1/04
摘要: A water extractable ophthalmic device is disclosed which is a polymerization product of a monomeric mixture comprising: (a) one or more cyclic lactams; (b) one or more non-bulky organosilicon-containing monomers; (c) one or more bulky siloxane monomers; and (d) a crosslinking agent mixture comprising (i) one or more first crosslinking agents containing at least two ethylenically unsaturated reactive end groups, wherein the at least two ethylenically unsaturated reactive end groups are (meth)acrylate-containing reactive end groups and (ii) one or more second crosslinking agents containing at least two ethylenically unsaturated reactive end groups wherein at least one of the ethylenically unsaturated reactive end groups is a non-(meth)acrylate reactive end group. The water extractable ophthalmic device has an equilibrium water content of at least about 50 wt. %, a contact angle of less than about 50°, and an oxygen permeability of at least about 60 Barrers.
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