公开(公告)号：US20150056326A1

公开(公告)日：2015-02-26

申请号：US14081119

申请日：2013-11-15

Applicant: Benjamin Alexander ,  Garth Cambray

Inventor： Benjamin Alexander ,  Garth Cambray

IPC: C12G3/02 ,  C12G1/022

CPC classification number: C12G3/02 ,  C12C11/075 ,  C12C11/09 ,  C12G1/0203 ,  C12M21/12 ,  C12M25/18 ,  C12M25/20 ,  C12M33/14 ,  C12P7/06 ,  Y02E50/17

Abstract: A hybrid continuous fermentation system and related process for fermenting sugars to produce alcohol containing liquors. The system includes a fermentor arranged with a packed bed region and a fluidized bed region. A yeast bed is retained in the packed bed region using a retention matrix and flocculation. A sugar supply is directed through the yeast bed with sufficient dwell time for satisfactory sugar conversion. The fluidized bed region is arranged to allow fermented product to pass through the fermentor while allowing yeast cell growth and retention. A nutrient may be added to the fermentor to aid in yeast flocculation. The fermentor is sized and shaped to allow sufficient dwell time of the sugar supply in the packed bed region and in the fluidized bed region to maximize sugar conversion to ethanol by fermentation.

Abstract translation: 一种混合连续发酵系统和相​​关方法，用于发酵糖以产生含醇的液体。 该系统包括布置有填充床区域和流化床区域的发酵罐。 使用保留基质和絮凝将酵母床保留在填充床区域中。 糖供应被引导通过酵母床具有足够的停留时间以获得令人满意的糖转化。 布置流化床区域以允许发酵产物通过发酵罐，同时允许酵母细胞生长和保留。 可以向发酵罐中加入营养物以帮助酵母絮凝。 发酵罐的尺寸和形状适于允许在填充床区域和流化床区域中的糖供应的足够的停留时间以通过发酵使糖转化成乙醇最大化。

公开(公告)号：US20070048863A1

公开(公告)日：2007-03-01

申请号：US11492445

申请日：2006-07-25

Applicant: Seth Rodgers ,  Fan Zhang ,  Mohamed Shaheen ,  Benjamin Alexander

Inventor： Seth Rodgers ,  Fan Zhang ,  Mohamed Shaheen ,  Benjamin Alexander

IPC: C12N5/06 ,  G06F19/00

CPC classification number: C12M41/48 ,  G16B50/00

Abstract: Computer-facilitated design of large-scale, multi-factorial cell culture experiments and the like, and control of reaction sites and/or arrays of reaction sites to perform such experiments using automated devices. In certain cases, the invention is directed to controlling a plurality of cell culture experiments, e.g., using an automated cell culture device. In one set of embodiments, a data structure or a “descriptor” for use with cell culture experiments is provided. The descriptor may be used, for instance, to control one or more cell culture experiments, to identify one or more cell culture experiments, and/or to identify or “tag” data arising from one or more cell culture experiments, e.g., for further analysis or recall.

Abstract translation: 大规模，多因素细胞培养实验等的计算机辅助设计，以及反应位点和/或反应位点阵列的控制，以使用自动化装置进行这种实验。 在某些情况下，本发明涉及控制多种细胞培养实验，例如使用自动细胞培养装置。 在一组实施例中，提供了用于细胞培养实验的数据结构或“描述符”。 描述符可以用于例如控制一个或多个细胞培养实验，以鉴定一个或多个细胞培养实验，和/或识别或“标记”由一个或多个细胞培养实验产生的数据，例如进一步 分析或召回。

公开(公告)号：US20100124584A1

公开(公告)日：2010-05-20

申请号：US12274447

申请日：2008-11-20

Applicant: Benjamin Alexander ,  Garth Anton Cambray ,  Eli Cayer

Inventor： Benjamin Alexander ,  Garth Anton Cambray ,  Eli Cayer

IPC: C12G3/02 ,  C12P7/06

CPC classification number: C12G3/02 ,  C12C11/075 ,  C12C11/09 ,  C12G1/0203 ,  C12M21/12 ,  C12M25/18 ,  C12M25/20 ,  C12M33/14 ,  C12P7/06 ,  Y02E50/17

Abstract: A hybrid continuous fermentation system and related process for fermenting sugars to produce alcohol containing liquors. The system includes a fermentor arranged with a packed bed region and a fluidized bed region. A yeast bed is retained in the packed bed region using a retention matrix and flocculation. A sugar supply is directed through the yeast bed with sufficient dwell time for satisfactory sugar conversion. The fluidized bed region is arranged to allow fermented product to pass through the fermentor while allowing yeast cell growth and retention. A nutrient may be added to the fermentor to aid in yeast flocculation. The fermentor is sized and shaped to allow sufficient dwell time of the sugar supply in the packed bed region and in the fluidized bed region to maximize sugar conversion to ethanol by fermentation.

Abstract translation: 一种混合连续发酵系统和相​​关方法，用于发酵糖以产生含醇的液体。 该系统包括布置有填充床区域和流化床区域的发酵罐。 使用保留基质和絮凝将酵母床保留在填充床区域中。 糖供应被引导通过酵母床具有足够的停留时间以获得令人满意的糖转化。 布置流化床区域以允许发酵产物通过发酵罐，同时允许酵母细胞生长和保留。 可以向发酵罐中加入营养物以帮助酵母絮凝。 发酵罐的尺寸和形状适于允许在填充床区域和流化床区域中的糖供应的足够的停留时间以通过发酵使糖转化成乙醇最大化。