公开(公告)号：US20210071124A1

公开(公告)日：2021-03-11

申请号：US16920365

申请日：2020-07-02

Applicant: Berkeley Lights, Inc.

Inventor： Randall D. LOWE, JR. ,  Kristin G. BEAUMONT ,  Aathavan KARUNAKARAN ,  Natalie C. MARKS ,  Jason M. MCEWEN ,  Mark P. WHITE ,  J. Tanner NEVILL ,  Gang F. WANG ,  Andrew W. MCFARLAND ,  Daniele Malleo ,  Keith J. BREINLINGER ,  Xiao GUAN ,  Kevin T. CHAPMAN

IPC: C12M3/06 ,  C12M1/00

Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.

公开(公告)号：US20220356429A1

公开(公告)日：2022-11-10

申请号：US17743318

申请日：2022-05-12

Applicant: Berkeley Lights, Inc.

Inventor： Randall D. LOWE, JR. ,  Kristin G. BEAUMONT ,  Aathavan KARUNAKARAN ,  Natalie C. MARKS ,  Jason M. MCEWEN ,  Mark P. WHITE ,  J. Tanner NEVILL ,  Gang F. WANG ,  Andrew W. MCFARLAND ,  Daniele Malleo ,  Keith J. BREINLINGER ,  Xiao GUAN ,  Kevin T. CHAPMAN

IPC: C12M3/06 ,  C12M1/00

Abstract: Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.

公开(公告)号：US20170114316A1

公开(公告)日：2017-04-27

申请号：US15282923

申请日：2016-09-30

Applicant: Berkeley Lights, Inc.

Inventor： Russell A. NEWSTROM ,  Andrew W. MCFARLAND ,  Darcy K. KELLY-GREENE ,  J. Tanner NEVILL ,  Gang F. WANG

IPC: C12M1/00 ,  C12M1/36 ,  C12M3/00 ,  C12M1/34 ,  C12M1/32 ,  C12M1/02

CPC classification number: C12M41/14 ,  C12M23/12 ,  C12M23/38 ,  C12M23/46 ,  C12M37/04 ,  C12M41/22 ,  C12M41/32 ,  C12M41/34 ,  C12M41/48

Abstract: Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed. The enclosure includes a plurality of openings configured to allow access to the wells. The incubators include a sealing element configured to seal the plurality of openings in the enclosure. The sealing element comprises a plurality of openings corresponding to at least a subset of the plurality of openings in the enclosure. Access to the internal chamber can be provided by aligning the plurality of openings in the sealing element with the plurality of openings in the enclosure. Methods for using the incubators are also provided.

公开(公告)号：US20230242860A1

公开(公告)日：2023-08-03

申请号：US17936478

申请日：2022-09-29

Applicant: Berkeley Lights, Inc.

Inventor： Russell A. NEWSTROM ,  Andrew W. MCFARLAND ,  Darcy K. KELLY-GREENE ,  J. Tanner NEVILL ,  Gang F. WANG

IPC: C12M1/00 ,  C12M1/12 ,  C12M1/32 ,  C12M3/00 ,  C12M1/02 ,  C12M1/34 ,  C12M1/36

CPC classification number: C12M41/14 ,  C12M23/12 ,  C12M23/38 ,  C12M23/46 ,  C12M37/04 ,  C12M41/22 ,  C12M41/32 ,  C12M41/34 ,  C12M41/48

Abstract: Incubators including an enclosure with an internal chamber configured to support a cell culture plate comprising a plurality of wells are disclosed. The enclosure includes a plurality of openings configured to allow access to the wells. The incubators include a sealing element configured to seal the plurality of openings in the enclosure. The sealing element comprises a plurality of openings corresponding to at least a subset of the plurality of openings in the enclosure. Access to the internal chamber can be provided by aligning the plurality of openings in the sealing element with the plurality of openings in the enclosure. Methods for using the incubators are also provided.