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    PROTEIN QUANTITATION DEVICE
    2.
    发明申请
    PROTEIN QUANTITATION DEVICE 有权

    公开(公告)号：US20230026156A1

    公开(公告)日：2023-01-26

    申请号：US17877680

    申请日：2022-07-29

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Evan THRUSH ,  Steven SWIHART ,  William STRONG ,  Trey MARLOWE ,  Li LU

    IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

    Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

    SEQUENTIAL MULTIPLEX WESTERN BLOTTING
    3.
    发明申请
    SEQUENTIAL MULTIPLEX WESTERN BLOTTING 审中-公开

    公开(公告)号：US20200209229A1

    公开(公告)日：2020-07-02

    申请号：US16722706

    申请日：2019-12-20

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： William STRONG ,  Eli HEFNER

    IPC: G01N33/543 ,  G01N33/58 ,  C12Q1/6869 ,  C12Q1/6834

    Abstract: Described are methods and compositions for sequential multiplex detection of target analytes in a sample. The method comprises contacting the sample comprising analytes immobilized on a solid support with binding agents that specifically bind an analyte in the sample, wherein each of the binding agents binds a different analyte and is attached to a single-stranded nucleic acid molecule comprising a unique sequence. The sample is then contacted with a labeled complementary nucleic acid molecule that binds the single-stranded nucleic acid molecule attached to one binding agent. The signal from the label is detected, and then reduced or eliminated. The sample can be simultaneously contacted with a second labeled complementary nucleic acid molecule that binds a different binding agent, and the signal from the second label is detected. The process is repeated for each additional analyte in the sample, thereby sequentially detecting the presence of the analytes in the sample.

    DIP-STICK WESTERN BLOT
    4.
    发明申请
    DIP-STICK WESTERN BLOT 审中-公开

    公开(公告)号：US20190025250A1

    公开(公告)日：2019-01-24

    申请号：US16138860

    申请日：2018-09-21

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： William STRONG

    IPC: G01N27/447 ,  G01N33/543 ,  G01N30/90

    Abstract: Methods, kits, and systems are provided for separating, immobilizing, and/or detecting analytes of one or more samples using dipsticks. A ‘dipstick’ is an object that can be embedded and subsequently removed from a separation medium, and to which analytes can be immobilized while the object is embedded in the separation medium. Examples of separation media include an electrophoresis gel of any format and a stationary phase for column chromatography. Embodiments of the present methods include applying a sample to a separation medium; separating analytes of the sample in the separation medium along a separation axis; immobilizing the analytes on a dipstick embedded in the separation medium; removing the dipstick from the separation medium; and detecting the analytes immobilized on the removed dipstick.

    PROTEIN QUANTITATION DEVICE
    6.
    发明申请
    PROTEIN QUANTITATION DEVICE 有权

    公开(公告)号：US20210199568A1

    公开(公告)日：2021-07-01

    申请号：US17199312

    申请日：2021-03-11

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Evan THRUSH ,  Steven SWIHART ,  William STRONG ,  Trey MARLOWE ,  Li LU

    IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

    Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

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